Use of athrombogenic tubing for perfusion rewarming following surface-induced deep hypothermia.
J Thorac Cardiovasc Surg
; 77(2): 277-82, 1979 Feb.
Article
em En
| MEDLINE
| ID: mdl-762968
ABSTRACT
A method of heparinless, oxygenatorless, left heart bypass perfusion rewarming following surface hypothermia, with the use of a closed circuit with 130 ml. prime volume including heat exchanger, has been devised. The use of polyurethane-polyvinyl-graphite (PPG)-coated tubing has previously been reported. In this text, the use of an athrombogenic coating with cetyl-pyridinium chloride (CPC) as a regional heparin carrier was studied in dogs, comparing groups with PPG tubing and total systemic heparinization or plain polyvinyl tubing without systemic heparinization. Heparin compounded in the CPC coating eluted into the blood and caused mild transient whole-body heparinization during rewarming from 20 degrees to 25 degrees C., as evidenced by prolongation of the thrombin time. Alterations of hematologic parameters in all three groups were similar to those during surface rewarming except for those affected by heparinization. The left heart bypass method was found useful for hypothermic open-heart surgery when utilized with an athrombogenic surface coating or total body heparinization. It was concluded that the CPC coating is superior to the PPG coating since no cracking surface develops, it is translucent, and it provides a more effective athrombogenic surface.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Perfusão
/
Compostos de Piridínio
/
Trombose
/
Heparina
/
Cetilpiridínio
/
Hipotermia Induzida
/
Intubação
Limite:
Animals
Idioma:
En
Ano de publicação:
1979
Tipo de documento:
Article