Gene clusters encoding the cytotoxic necrotizing factor type 1, Prs-fimbriae and alpha-hemolysin form the pathogenicity island II of the uropathogenic Escherichia coli strain J96.
FEMS Microbiol Lett
; 126(2): 189-95, 1995 Feb 15.
Article
em En
| MEDLINE
| ID: mdl-7705611
ABSTRACT
The uropathogenic Escherichia coli strain J96 (04K6) is able to produce four adherence factors [P-fimbriae (pap and prs), F1C-fimbriae (foc) and Type 1-fimbriae (fim)], two alpha-hemolysins (hlyI and II) and the cytotoxic necrotizing factor type 1 (cnf1). Using phenotypic test systems and genotypic analysis, it has been shown that the mutant strain J96-M1 has lost the hlyII, prs and cnf1 genes. The three virulence associated determinants are linked on one particular region on the chromosome, which is termed 'pathogenicity island II' (Pai II).
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01-internacional
Base de dados:
MEDLINE
Assunto principal:
Toxinas Bacterianas
/
Adesinas Bacterianas
/
Proteínas de Escherichia coli
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Citotoxinas
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Escherichia coli
/
Proteínas Hemolisinas
Idioma:
En
Ano de publicação:
1995
Tipo de documento:
Article