Tissue reaction on PLLA versus stainless steel interlocking nails for fracture fixation: an animal study.
Biomaterials
; 16(2): 103-6, 1995 Jan.
Article
em En
| MEDLINE
| ID: mdl-7734641
ABSTRACT
In order to develop a biodegradable interlocking nail for fracture fixation, polylactic acid (PLLA) rods were implanted in the femoral bone of young pigs. A midshaft osteotomy was performed in order to mimic a fracture. The tissue response to PLLA rods versus stainless steel rods was studied after 1 and 3 months of implantation. Fracture-healing characteristics and chemical and mechanical properties of the PLLA rods were studied after explantation. Mechanical properties deteriorated during implantation and chemical properties changed significantly in 1 and 3 months of implantation. PLLA and stainless steel induced a similar tissue reaction during the studied implantation time of 3 months.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polímeros
/
Aço Inoxidável
/
Pinos Ortopédicos
/
Teste de Materiais
/
Ácido Láctico
/
Fixação Intramedular de Fraturas
/
Lactatos
Limite:
Animals
Idioma:
En
Ano de publicação:
1995
Tipo de documento:
Article