[Iminodimethylation, a method for pharmacomodulation in pyrimido-[3,4-a]-s-triazine series]. / L'iminodiméthylation, une méthode de pharmacomodulation en série pyrimido [3,4-a]-s-triazinique.
Ann Pharm Fr
; 53(1): 29-37, 1995.
Article
em Fr
| MEDLINE
| ID: mdl-7741424
ABSTRACT
Primary amines react with two formaldehydes and compounds presenting two mobile hydrogen atoms, this reaction can be called iminodimethylation. This reaction can be used in order to perform a pharmacomodulation in the pyrimido [3,4-a]-s-triazine series. Against Epidermophyton floccosum, the activity is better when nitrogen 7 is not substituted, when the heroatom in position 2 is 0 instead of S and when an aromatic nucleus is directly linked to the nitrogen atom in position 3.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bactérias
/
Antifúngicos
Idioma:
Fr
Ano de publicação:
1995
Tipo de documento:
Article