[Effects of captopril on platelet-derived growth factor ligand and receptor gene expression of vascular wall after balloon angioplasty].
Zhonghua Yi Xue Za Zhi
; 75(2): 79-81, 125, 1995 Feb.
Article
em Zh
| MEDLINE
| ID: mdl-7767772
ABSTRACT
A predominant fibromuscular plaque was produced by balloon catheter denuding angioplasty of both iliac arteries and feeding cholesterol in 16 New Zealand white rabbits. Balloon angioplasty was performed in model animals. Captopril-treated (n = 8, captopril 12.5 mg.kg-1/d) group which received captopril 7 days before to 4 wk after angioplasty were examined by dot blot hybridization. The results showed that captopril can inhibit platelet-derived growth factor ligand and receptor gene expression of vascular wall after balloon angioplasty.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arteriosclerose
/
Fator de Crescimento Derivado de Plaquetas
/
Captopril
/
Receptores do Fator de Crescimento Derivado de Plaquetas
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
Zh
Ano de publicação:
1995
Tipo de documento:
Article