[Diltiazem helps perfusion of the kidney after transplantation: intraoperative assessment using echo-color Doppler]. / Il diltiazem favorisce la perfusione del rene dopo il trapianto: valutazione intraoperatoria mediante eco-color-Doppler.

ABSTRACT

Diltiazem is a dihydropyridinic calcium-antagonist which acts an arterial muscle, producing an increase in vascular capacity. We administered it intraoperatively in 2 patients subjected to kidney transplantation, to asses the maximal vascular reserve of the transplanted organ. After 2' and 10' from administration of Diltiazem, Color Doppler Ultrasound showed a 30% increase in mean flow in the renal artery and 13% reduction in the intraparenchymal resistance rates with respect to the basal parameters. Systemic arterious pressure remained unchanged. This result was associated with an improvement in the perfusion of the transplanted organ.