A rat model of phencyclidine psychosis.
Life Sci
; 55(21): 1605-10, 1994.
Article
em En
| MEDLINE
| ID: mdl-7968234
ABSTRACT
Phencyclidine (PCP)-induced behavior in rats was investigated in water maze and diving behavior tasks. The swimming and diving latencies of PCP-treated groups placed in a water maze apparatus were gradually shortened, and prolonged, respectively, while rats in a control group performed well. In all rats, stereotyped behavior and hyperlocomotion were absent. We propose that this animal model induced by lower doses of PCP may be useful for further studies to research schizophrenia.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fenciclidina
/
Psicoses Induzidas por Substâncias
/
Comportamento Animal
/
Modelos Animais de Doenças
/
Memória
Limite:
Animals
Idioma:
En
Ano de publicação:
1994
Tipo de documento:
Article