Radiotherapy in early stage Hodgkin's disease.
Leuk Lymphoma
; 13(3-4): 285-9, 1994 Apr.
Article
em En
| MEDLINE
| ID: mdl-8049650
ABSTRACT
Ninety-nine patients with "standard risk" Stage IA-IIA Hodgkin's disease observed between January 1983 and December 1990, received radiotherapy only. The complete response rate was 98% (97/99). Twenty-one patients (21%) relapsed, 17 of whom (81%) obtained a second complete remission. The projected 9-year overall survival and disease-free survival were 95% and 78%, respectively. In this study our goals were to reduce the irradiation volumes, to decrease the number of splenectomies performed at diagnosis, and to utilize radiotherapy alone in these patients. We were able to reduce the irradiation volumes in over 50% and 80% of the patients with disease in the upper torso and subdiaphragm, respectively. Furthermore, this therapeutic approach permitted us to reduce the acute and long-term toxic effects related to splenectomy and combined modality treatment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Teleterapia por Radioisótopo
/
Doença de Hodgkin
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Radioisótopos de Cobalto
Limite:
Adolescent
/
Adult
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Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
1994
Tipo de documento:
Article