[Study of primary resistance to antitubercular drugs in Galicia]. / Estudio de las resistencias primarias a fármacos antituberculosos en Galicia.
Arch Bronconeumol
; 30(6): 297-300, 1994.
Article
em Es
| MEDLINE
| ID: mdl-8087389
ABSTRACT
The primary resistance of 100 specimens of Mycobacterium tuberculosis isolated in patients with active tuberculosis confirmed bacteriologically was studied prospectively over a period of 15 months. Strains resistant to 1 or more drugs were found in 5 patients. Three patients presented resistance to 2 drugs (isoniazide and streptomycin in 2 and rifampicin and isoniazid, streptomycin and ethambutol); and the fifth was resistant only to pyrazinamide. Owing to the few instances of primary resistance found, it was impossible to establish whether any of the factors analyzed in each patient was related to a higher index of resistance, although 4 of the 5 resistant strains came from respiratory specimens. We conclude that the index of primary resistance in our area is low and this allows us to do without prescribing a fourth drug in the first two months of anti-tuberculosis therapy, and makes routine sensitivity tests unnecessary for patients with no history of prior treatment for tuberculosis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Mycobacterium tuberculosis
/
Antituberculosos
Tipo de estudo:
Observational_studies
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
Es
Ano de publicação:
1994
Tipo de documento:
Article