Syntheses of all the possible monomethyl ethers and several deoxyhalo analogues of methyl beta-lactoside as ligands for the Ricinus communis lectins.
Carbohydr Res
; 254: 61-79, 1994 Feb 17.
Article
em En
| MEDLINE
| ID: mdl-8180997
ABSTRACT
The synthesis of all the possible monomethyl ethers of methyl beta-lactoside (1) has been performed from 1 in a straightforward way, making use of the different reactivity of the hydroxyl groups in alkylation and stannylation reactions. In addition, the deoxyfluoro derivatives of 1 at positions, 6,3',4',epi-4', and 6' have been prepared by reaction of the appropriate substrates with diethylaminosulfur trifluoride or tetrabutylammonium fluoride. Finally, the 6-deoxyiodo and 6'-bromodeoxy analogues of 1 have also been prepared.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ricina
/
Dissacarídeos
/
Ligantes
/
Metilglicosídeos
Idioma:
En
Ano de publicação:
1994
Tipo de documento:
Article