Changes in peripheral blood lymphocyte subset frequencies in myasthenia gravis patients are related to immunosuppression.
J Neurol
; 241(4): 218-22, 1994 Feb.
Article
em En
| MEDLINE
| ID: mdl-8195820
ABSTRACT
Surface antigens on peripheral blood lymphocytes from myasthenia gravis patients were investigated. The expression of DR+ and CD8+/DR+ T lymphocytes was increased and the expression of CD4+ T cells reduced. Neither thymectomy, clinical condition nor anti-acetylcholine receptor antibody titre correlated with any of the changes in peripheral blood lymphocyte subsets observed. However, immunosuppressive therapy correlated with the significant reduction in CD4+ and CD2+/CD4+ T cells in these patients.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Autoimunes
/
Subpopulações de Linfócitos T
/
Miastenia Gravis
Limite:
Adolescent
/
Aged
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1994
Tipo de documento:
Article