Repeated gestational trophoblastic disease after natural and heterologous assisted conception. A case report.

We report the case of a woman with a familial history of gestational trophoblastic disease who developed repeated partial and complete moles after fertilization by her husband and heterologous assisted conception. This case has interesting etiologic implications, but it is difficult to make any extrapolation from this very peculiar case in terms of definition/quantification of maternal and paternal components in the development of gestational trophoblastic disease.