Structure of the gene encoding rat neutrophil chemo-attractant Gro.
Gene
; 126(2): 285-6, 1993 Apr 30.
Article
em En
| MEDLINE
| ID: mdl-8482545
ABSTRACT
A cloned rat gro gene encoding the neutrophil chemo-attractant Gro was isolated from a lambda Charon4A rat genomic library, and the nucleotide (nt) sequence of a 2500-bp fragment encompassing the coding region and 3'- and 5'-flanking regions was determined. The gene consisted of four exons separated by three introns. The transcription start point was determined by primer-extension analysis and found to be a G located 72 nt upstream from the start codon. The 5'-flanking region of the gene contained a 'TATA'-like structure and an NF-kappa B-binding sequence.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fatores Quimiotáticos
/
Substâncias de Crescimento
/
Quimiocinas CXC
/
Peptídeos e Proteínas de Sinalização Intercelular
/
Neutrófilos
Limite:
Animals
Idioma:
En
Ano de publicação:
1993
Tipo de documento:
Article