Elevated serum alpha-fetoprotein in a patient with undifferentiated carcinoma of the gall bladder.
J Clin Pathol
; 48(11): 1061-3, 1995 Nov.
Article
em En
| MEDLINE
| ID: mdl-8543634
ABSTRACT
An uncommon case of undifferentiated carcinoma of the gall bladder in a 65 year old Chinese man, who presented with an increased serum alpha-fetoprotein concentration, is reported. Histologically, the tumour had a primitive appearance and was composed of a pavement-like array of poorly differentiated columnar/polygonal cells. Alpha-fetoprotein was demonstrated in some of the tumour cells using an immunoperoxidase technique. Alpha-fetoprotein secretion in this instance may have occurred because the gall bladder and the liver are of similar embryological origin. Alpha-fetoprotein may also be related to the resurgent expression of oncofetal antigens. This tumour may represent another rare cause of increased serum alpha-fetoprotein concentrations.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carcinoma
/
Alfa-Fetoproteínas
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Biomarcadores Tumorais
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Neoplasias da Vesícula Biliar
Limite:
Aged
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Humans
/
Male
Idioma:
En
Ano de publicação:
1995
Tipo de documento:
Article