Expression of inositol 1,4,5-trisphosphate receptors in rat adrenocortical zones.
J Steroid Biochem Mol Biol
; 57(1-2): 13-7, 1996 Jan.
Article
em En
| MEDLINE
| ID: mdl-8645612
ABSTRACT
Previously we demonstrated the presence of InsP3R-I, -II and -III subtypes in the zona glomerulosa. Now we have examined the expression of different subtypes of inositol 1,4,5-trisphosphate receptor (InsP3R) in the inner zones of rat adrenal cortex. RNA extracted from decapsulated adrenal tissue (zonae fasciculata-reticularis and the medulla) or from fasciculata-reticularis cells was reverse transcribed. Subsequent polymerase chain reaction revealed the presence of InsP3R-I, -II and -III subtypes in decapsulated tissue but failed to demonstrate the expression of any known subtypes of InsP3R in fasciculata-reticularis cells. Accordingly, InsP3 receptors expressed in the decapsulated tissue are of medullary origin.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Canais de Cálcio
/
Zona Fasciculada
/
Zona Reticular
/
Receptores Citoplasmáticos e Nucleares
Limite:
Animals
Idioma:
En
Ano de publicação:
1996
Tipo de documento:
Article