Monoclonal gammopathies antigen driven in autoimmune diseases.
Clin Exp Rheumatol
; 14 Suppl 14: S37-44, 1996.
Article
em En
| MEDLINE
| ID: mdl-8722198
ABSTRACT
An important link exists between cancer, autoimmune diseases and immune deficiency. This presentation will review some data concerning clonal growth in B lymphocytes, with focus on the occurrence of autoantibody f2p4vity in the monoclonal proteins, which are the products of the clonally expanded lymphocyte plasma cell population. The role of antigen in causing or promoting monoclonal B cell growth is considered for several different forms of monoclonal gammopathies benign, malignant, and secondary. There is recent demonstration of M-proteins and clonal growth complicating HIV infections and some autoimmune conditions which illustrate well the link between cancer, autoimmunity and immune deficiency.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Paraproteinemias
/
Autoantígenos
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
1996
Tipo de documento:
Article