Neutrophilic hypersegmentation as an indicator of incipient folic acid deficiency.
Am J Clin Pathol
; 68(2): 263-7, 1977 Aug.
Article
em En
| MEDLINE
| ID: mdl-879101
ABSTRACT
The authors have identified a group of subjects with neutrophilic hypersegmentation who are normal or near-normal with respect to other hematologic indices (hemoglobin, mean corpuscular volume). In a high proportion of these subjects, serum folate levels are abnormally low. In this group and a non-hypersegmented-neutrophil control group there was a significant negative correlation between average numbers of neutrophilic lobes and serum folate levels. In the subjects with hypersegmented neutrophils the predominant alteration is a shift from three-lobed to five-lobed neutrophils. It is believed that neutrophilic hypersegmentation can be a valuable adjunct in documenting and/or uncovering incipient folate deficiency.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Deficiência de Ácido Fólico
/
Neutrófilos
Tipo de estudo:
Prognostic_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1977
Tipo de documento:
Article