trk-like immunoreactivity in the human trigeminal ganglion and subnucleus caudalis.
Neuroreport
; 7(5): 1013-9, 1996 Apr 10.
Article
em En
| MEDLINE
| ID: mdl-8804042
ABSTRACT
The immunohistochemical occurrence of trkA, trkB and trkC receptors was examined in the human trigeminal ganglion and spinal nucleus of subjects at all ages and compared with that of substance P (SP) and calcitonin gene-related peptide (CGRP), trk-like immunoreactive (LI) material was detectable in discrete subpopulations of primary sensory neurones from 25 weeks of gestation to adult life. Each subpopulation overlapped partially with those immunoreactive to SP and CGRP, trkA- and trkC-positive filamentous and punctate elements occurred in the trigeminal subnucleus caudalis. While immunostaining for trkC was restricted to rare isolated elements, that for trkA outlined the superficial laminae of the nucleus and was more intense early in life than in adults.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Núcleo Inferior Caudal do Nervo Trigêmeo
/
Gânglio Trigeminal
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Proteínas Proto-Oncogênicas
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Receptores de Fator de Crescimento Neural
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Receptores Proteína Tirosina Quinases
Limite:
Aged
/
Aged80
/
Female
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Humans
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Male
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Middle aged
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Newborn
Idioma:
En
Ano de publicação:
1996
Tipo de documento:
Article