A comparison of doxorubicin and COP for maintenance of remission in cats with lymphoma.
J Vet Intern Med
; 10(6): 372-5, 1996.
Article
em En
| MEDLINE
| ID: mdl-8947869
ABSTRACT
Thirty-eight cats with lymphoma were treated with vincristine, cyclophosphamide, and prednisone (COP). They were randomized at entry to receive maintenance chemotherapy consisting of either single-agent doxorubicin or continued COP therapy, starting on week 4 of treatment and continuing for 6 months or until relapse. Eighteen cats achieved complete clinical remission after COP induction chemotherapy. The median remission duration for 11 cats continuing to receive COP was 83 days, which was significantly shorter than for 7 cats that received doxorubicin (281 days). Thus, doxorubicin should be considered a well-tolerated and efficacious agent for the maintenance of remission in cats with lymphoma.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Protocolos de Quimioterapia Combinada Antineoplásica
/
Doxorrubicina
/
Doenças do Gato
/
Linfoma
/
Antineoplásicos
Limite:
Animals
Idioma:
En
Ano de publicação:
1996
Tipo de documento:
Article