Use of liver allografts from carbon monoxide poisoned cadaveric donors.
Transplantation
; 62(10): 1514-5, 1996 Nov 27.
Article
em En
| MEDLINE
| ID: mdl-8958283
ABSTRACT
Carbon monoxide (CO) inhalation leads to cerebral, cardiac, and, more rarely, liver damage. The use of liver allografts from CO poisoned donors with evidence of liver damage has not previously been reported. In this report we describe two recipients, both in fulminant hepatic failure, who received liver grafts from such donors. One donor had markedly abnormal liver function tests (LFTS), and in the other LFTS were mildly abnormal. In both, the liver appeared normal at procurement. There was satisfactory early function of both allografts, although marked patchy necrosis was seen on the postreperfusion biopsy (case 1), and on a 10 day postoperative biopsy (case 2). In both cases the changes were considered to be related to damage sustained from CO inhalation. Both allografts soon achieved normal function and both recipients are well. We conclude that CO poisoning can cause liver damage that can recover completely following liver transplantation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Intoxicação por Monóxido de Carbono
/
Transplante de Fígado
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Ano de publicação:
1996
Tipo de documento:
Article