Your browser doesn't support javascript.
loading
Vitamin D stores of urban women in Taipei: effect on bone density and bone turnover, and seasonal variation.
Tsai, K S; Hsu, S H; Cheng, J P; Yang, R S.
Afiliação
  • Tsai KS; Department of Laboratory Medicine, College of Medicine, National Taiwan University, Taipei, Republic of China.
Bone ; 20(4): 371-4, 1997 Apr.
Article em En | MEDLINE | ID: mdl-9108358
This study was performed to survey the vitamin D nutritional status of urban Chinese women, and to define its role in determining bone metabolic rate and bone mineral density (BMD). We measured serum 25-hydroxyvitamin D (25-OHD), the major storage form of vitamin D, and BMD, at the spine, hip, and total body skeleton, of 262 healthy Chinese women aged from 40 to 72 years, residing in Taipei city. Bone turnover markers, including serum osteocalcin, bone alkaline phosphatase isozyme, and C-terminal propeptide of type I procollagen, and a urinary bone resorption marker, N-terminal crosslinked fragment of type I collagen, were also measured. We found generally adequate vitamin D nutritional stores. The mean concentration of serum 25-OHD was 30.7 (SD = 8.2) ng/mL for all 262 subjects and there were no significant age-related changes. Those who had serum sampled during the summer showed higher serum 25-OHD levels (N = 138; mean +/- SD: 32.7 +/- 7.6 ng/mL) than those who had serum sampled during winter (N = 124; mean +/- SD: 28.5 +/- 8.3 ng/mL; Student's t-test, p < 0.001), but these two groups showed similar BMD and bone marker values. Those with serum 25-OHD concentration in the lowest or highest tertile did not show different BMD or bone marker values than those in the other tertiles. Multiple regression demonstrated no correlation between 25-OHD and any bone marker or BMD at any site. Thus, in this free-living urban Chinese population, in a subtropical region, we could not demonstrate a role of vitamin D stores in determining bone turnover rate or BMD in women aged 40-70 years.
Assuntos
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Coluna Vertebral / Vitamina D / Densidade Óssea / Fêmur Limite: Adult / Aged / Female / Humans / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 1997 Tipo de documento: Article
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Coluna Vertebral / Vitamina D / Densidade Óssea / Fêmur Limite: Adult / Aged / Female / Humans / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 1997 Tipo de documento: Article