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Pulmonary tuberculosis after lung transplantation.
Schulman, L L; Scully, B; McGregor, C C; Austin, J H.
Afiliação
  • Schulman LL; Department of Medicine, College of Physicians & Surgeons of Columbia University, New York, USA.
Chest ; 111(5): 1459-62, 1997 May.
Article em En | MEDLINE | ID: mdl-9149616
During a 5-year study period, we diagnosed pulmonary tuberculosis in two (2%) of 94 lung and heart-lung transplant recipients. Each infection occurred 3 months after bilateral lung transplantation in the presence of evidence implicating donor-to-recipient transmission of the pathogen. The radiographic patterns of pulmonary tuberculosis were subtle: narrowing of the middle lobe bronchus of the right lung caused by an endobronchial granulomatous mass (n = 1) and a focal cluster of small nodules in the upper lobe of the left lung and small bilateral pleural effusions (n = 1). Each patient achieved complete clinical and radiographic response after antituberculous therapy. We conclude that Mycobacterium tuberculosis may be transmitted directly by a donor lung and may involve bronchial mucosa, pulmonary parenchyma, and pleura.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose Pulmonar / Transplante de Pulmão Limite: Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 1997 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose Pulmonar / Transplante de Pulmão Limite: Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 1997 Tipo de documento: Article