Greater emotional distress is associated with accelerated CD4+ cell decline in HIV infection.
J Psychosom Res
; 42(4): 379-90, 1997 Apr.
Article
em En
| MEDLINE
| ID: mdl-9160277
An investigation was conducted to explore the relationship between emotional distress and HIV progression. One hundred twenty-five homosexual, HIV-positive males participated in a 12-month longitudinal investigation. Psychosocial data were collected at 6-month intervals and CD4+ data were collected from diagnosis to the end of the investigation. Principal component analyses were performed initially to identify factors of emotional distress and health status. In addition, CD4+ reliability assessments were performed to ensure the validity of the prognostic assessments made. As a result of these analyses, 47 individuals were eligible for the main analyses. The results from a stepwise regression revealed that disease progression was significantly predicted by CD4+ count at diagnosis (32% of variance) and emotional distress (17% of variance), but was unrelated to subjective perceptions of health. The data suggest that some of the variability in HIV progression can be attributed to emotional distress.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Soropositividade para HIV
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Contagem de Linfócito CD4
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Transtornos do Humor
Tipo de estudo:
Diagnostic_studies
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Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
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Aged
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
1997
Tipo de documento:
Article