[Large granular T-cell lymphocytic leukemia disclosed by bilateral uveitis: association with celiac disease]. / Leucémie à grands lymphocytes granuleux T révélée par une uvéite bilatérale: association à une maladie coeliaque.

ABSTRACT

A 70-year-old woman presented with bilateral anterior uveitis. She was on a gluten-free diet because of a celiac disease which had been diagnosed 3 months before. An anterior chamber aspirate contained a majority of large granular lymphocytes (LGL). The investigation of a chronic neutropenia led to the diagnosis of an otherwise typical T-LGL leukemia. This seems to be the first report of a CD3+ CD4- CD8+ T-LGL leukemia causing anterior uveitis through infiltration of leukemic cells, and the second report of an intriguing association of celiac disease with T-LGL leukemia.