[Functional reaction of a fibroblast surface protein (author's transl)]. / Funktionelle Reaktionen eines Oberflächenproteins von Fibroblasten.
Wien Klin Wochenschr
; 89(21): 728-9, 1977 Nov 11.
Article
em De
| MEDLINE
| ID: mdl-919560
ABSTRACT
Cold-insoluble globulin (CIG) of plasma represents the soluble form of a fibroblast surface protein. As shown by affinity chromatography it is selectively adsorbed from plasma on immobilized collagen of various types. The following sequence of binding strength between CIG and collagen was evaluated by means of fractionated elution collagen type III native less than type I native less than type I denatured. The affinity to native collagen is important for the capability of CIG to mediate the attachement of fibroplasts on collagen fibrils. In addition, CIG is a substrate of activated coagulation factor XIII which plays an important, but as yet unclarified role in wound healing.
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01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fibroblastos
/
Proteínas de Membrana
Idioma:
De
Ano de publicação:
1977
Tipo de documento:
Article