Effect of HLA matching on outcome of related and unrelated donor transplantation therapy for chronic myelogenous leukemia.
Hematol Oncol Clin North Am
; 12(1): 107-21, 1998 Feb.
Article
em En
| MEDLINE
| ID: mdl-9523228
ABSTRACT
This article examines the diversity and biologic role of human lymphocyte antigen (HLA) genes as related to marrow transplantation for chronic myelogenous leukemia (CML). A better understanding of the nature and function of HLA variation is necessary as unrelated marrow transplantation evolves into a safe and effective treatment for CML. HLA matching is an important aspect of donor selection criteria and has a role in engraftment as well as the development of graft-versus-host disease and tolerance after transplant.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doadores de Tecidos
/
Leucemia Mielogênica Crônica BCR-ABL Positiva
/
Transplante de Medula Óssea
/
Doença Enxerto-Hospedeiro
/
Antígenos HLA
Limite:
Humans
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article