Granule cell dispersion is correlated with early epileptic events in human temporal lobe epilepsy.
J Neurol Sci
; 154(2): 133-6, 1998 Feb 05.
Article
em En
| MEDLINE
| ID: mdl-9562302
ABSTRACT
Granule cell dispersion (GCD) into the dentate gyrus (DG) molecular layer was observed in hippocampal specimens in 10 out of 22 cases of human non-lesional temporal lobe epilepsy (TLE) and was associated with hippocampal sclerosis (HS). The presence of GCD was significantly linked to events of epileptic nature arising during the first 4 years of life but not with the durations of epilepsy, nor the number of seizures. Dispersion could be induced by seizure-linked structural plasticity occurring during a specific early permissive period.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esclerose Cerebral Difusa de Schilder
/
Giro Denteado
/
Epilepsia do Lobo Temporal
/
Neurônios
Tipo de estudo:
Clinical_trials
Limite:
Child
/
Humans
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article