Umbilical cord blood transplant from HLA-mismatched unrelated donor in high-risk leukemia.
Bone Marrow Transplant
; 21 Suppl 3: S85-6, 1998 Jun.
Article
em En
| MEDLINE
| ID: mdl-9712504
ABSTRACT
Twelve consecutive children with high-risk leukemia have been submitted to UCB transplant from unrelated 1 or 2 loci HLA-mismatched donor. All patients received an identical regimen for conditioning and GVHD prophylaxis. The median dose of viable nucleated cells infused was 2.8 x 10(7)/kg bw (range 1.4-7.9). Of 11 patients evaluable for engraftment, the hematopoiesis was of full donor origin in seven patients and autologous in four. The probability of disease-free survival at 1 and 2 years from UCB transplant is 60 and 42%, respectively.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Leucemia
/
Transplante de Células-Tronco Hematopoéticas
/
Sangue Fetal
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Adolescent
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Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article