Neurological manifestations and pathophysiological mechanisms of Covid-19

Background - Severe acute respiratory syndrome coronavirus-2 is a novel, highly infectious coronavirus and the etiologic agent of Covid-19. The course of Covid-19 can range from mild flu-like symptoms to severe, life-threateningsymptoms, especially when comorbidities are present. Increasing studies have reinforced the association between SARS-CoV-2 and various neurological manifestations, although the pathophysiological mechanisms remain uncertain. Objective - The aim of this paper was to briefly describe current findings on the relationship between SARS-CoV-2 pathophysiology and major CNS and Peripheral Nervous System (PNS) manifestations.Methods and Material - This work consists of a literature review based on the study of academic papers. To this end, the Pubmed platform was used to search for scientific articles, using the keywords: covid-19, coronavirus, physiopathology, neuronal symptoms. Results - out of 114,660 articles found, 94 were selected for this review. Conclusions - Periodic reviews collaborate in the constant updating and summarization of findings. Understanding the pathophysiology of SARS-CoV-2 on the SN and the link between the systems may lead to earlier and earlier diagnoses of neurological involvement, guide therapeutic management, prevent sequelae, and preserve lives(AU)

Trauma facial por arma de fogo com lesão simpática associada: relato de caso / Facial trauma by a firegun with sympathic lesion associated: case report

Relatamos o caso de um paciente que sofreu ferimento por arma de fogo na região do terço médio da face. Além das implicações decorrentes de um ferimento desse tipo, observou-se o envolvimento de nervos simpáticos periféricos das glândulas sudoríparas causando sudorese cervicofacial homolateral