A utilizaçäo de antibióticos no tratamento da doença periodontal / The antibiotic using in the periodontal disease treatment

Com base nas observaçöes de que microrganismos específicos presentes na placa bacteriana säo o agente etiológico na doença periodontal e que algumas entidades de doença näo respondem adequadamente à terapêutica convencional (desbridamento mecânico), antibióticos têm sido utilizados como uma forma adjunta de terapia. Das drogas disponíveis, as tetraciclinas säo as que apresentam um maior número de dados, principalmente no tratamento da doença periodontal associada ao Actinobacillus actinomycetemcomitans. Outras drogas, como metronidazol, penicilinas, clindamicina e uma associaçäo destas têm sido estudadas. Este trabalho revê as principais aplicaçöes destes fármacos no tratamento da doença periodontal

Susceptibility of actinobacillus actinomycetemcomitans strains to norfloxacin / Suscetibilidade de linhagens de actnobacillus actinomycetemcomitans ao norfloxacino

The minimal inhibitory concentration of norfloxacin to Actinobacillus actinomycetemcomitans strains isolated from patients with localized juvenile periodontitis was determined by using an agar dilution method. All the tested strains, including the three reference strains, were susceptible at concentrations lower than the breakpoint used, with 90 percent of the strains susceptible to 0.125 µg/ml

Actinobacillus actinomycetemcomitans in Brazilian insulin-dependent individuals with diabetes mellitus

The prevalence of Actinobacillus Actinomycetemcomitans (Aa) in subgingival plaque specimens from 26 insulin-dependent diabetes mellitus patients, 11-25 years of age, was determined between January 1987 and December 1989. One hundred and thirty subgingival plaque samples were collected with sterile periodontal curettes. The specimens were weighed, diluted, inoculated on trypticase-soy-serum-bacitracin-vancomycin agar medium (TSBV) and incubated under microaerophilic conditions. Aa was isolated from 2.3//of healthy periodontal areas in these patients, while the microorganism was found in 12.5//of the sites with gingivitis and in 2.6//of the periodontal pockets examined. Although biochemical tests used for the characterization of Aa strains showed homogeneous results, different biotypes were isolated from one or more periodontal sites in the same patient

Intragingival occurrence of Actinobacillus actinomycetemcomitans and Bacteroides gingivalis in active destructive periodontal lesions / Ocorrência intragengival de Actinobacillus actinomycetencomitans e Bacteroides gengivais em lesões destrutivas periodontais ativas

A total of six active and six nonactive sites from six untreated periodontitis patients were examined for intragingival presence of Actinobacillus actinomycetemcomitans and Bacteroides gingivalis. The active destructive periodontal disease was determined by the "tolerance method." The method of immunoperoxidase was used in the identification of intragingival microorganisms in active and nonactive periodontal sites. Ligth microscopic sections of gingival tissues consecutive to those with gram stain, revealing presence of bacteria (substantiated by electron microscopy), were stained with peroxidase-labeled antibodies against A. actinomycetemcomitans and B. gingivalis. B. gingivalis was found to be significantly elevated in the connective tissue of active sites when compared to nonactive sites. A statistically significant border-line difference was found between active and nonactive sites in the connective tissue invaded by A. actinimycetemcomitans. Our findings plus the well established periodontopathic potential of A. actinomycetemcomitans and B. gingivalis support the concept that these bacteria are important invasive pathogenic agents in periodontitis

A importância do Actinobacillus actinomycetemcomitans na etiologia da periodontite juvenil localizada: revista da literatura / The importance of Actinobacillus actinomycetemicoitans on the localized juvenile periodontitis etiology: litrature review

Este trabalho tem por finalidade demonstrar através de uma revista da literatura, considerações sobre a importância do actinobacillus actinomycetemcomitans na etiologia da Periodontite Juvenil Localizada