Hospitalizations from covid-19: a health planning tool / Ingresos hospitalarios por covid-19: una herramienta de planificación sanitaria

ABSTRACT OBJECTIVE Estimate the future number of hospitalizations from Covid-19 based on the number of diagnosed positive cases. METHOD Using the covid-19 Panel data recorded in Spain at the Red Nacional de Vigilancia Epidemiológica, Renave (Epidemiological Surveillance Network), a regression model with multiplicative structure is adjusted to explain and predict the number of hospitalizations from the lagged series of positive cases diagnosed from May 11, 2020 to September 20, 2021. The effect of the time elapsed since the vaccination program starting on the number of hospitalizations is reviewed. RESULTS Nine days is the number of lags in the positive cases series with greatest explanatory power on the number of hospitalizations. The variability of the number of hospitalizations explained by the model is high (adjusted R2: 96.6%). Before the vaccination program starting, the expected number of hospitalizations on day t was 20.2% of the positive cases on day t-9 raised to 0.906. After the vaccination program started, this percentage was reduced by 0.3% a day. Using the same model, we find that in the first pandemic wave the number of positive cases was more than six times that reported on official records. CONCLUSIONS Starting from the covid-19 cases detected up to a given date, the proposed model allows estimating the number of hospitalizations nine days in advance. Thus, it is a useful tool for forecasting the hospital pressure that health systems shall bear as a consequence of the disease.

RESUMEN OBJETIVO Predecir el número futuro de hospitalizaciones por covid-19 a partir del número de casos positivos diagnosticados. MÉTODO Usando datos del Panel covid-19 registrados en España en la Red Nacional de Vigilancia Epidemiológica (Renave), se ajusta un modelo de regresión con estructura multiplicativa para explicar y predecir el número de hospitalizaciones a partir de la serie retardada de casos positivos diagnosticados durante el periodo entre el 11 de mayo de 2020 y el 20 de septiembre de 2021. Se analiza el efecto sobre el número de hospitalizaciones del tiempo transcurrido desde el inicio del programa de vacunación. RESULTADOS El número de retardos de la serie de casos positivos que mayor capacidad explicativa tiene sobre el número de hospitalizaciones es de nueve días. La variabilidad del número de hospitalizaciones explicada por el modelo es elevada (R2 ajustado: 96,6%). Antes del inicio del programa de vacunación, el número esperado de ingresos hospitalarios en el día t era igual al 20,2% de los casos positivos del día t-9 elevado a 0,906. Iniciado el programa de vacunación, este porcentaje se redujo un 0,3% diario. Con el mismo modelo se obtiene que en la primera ola de la pandemia el número de casos positivos fue más de seis veces el que figura en los registros oficiales. CONCLUSIONES Partiendo de los casos de covid-19 detectados hasta una fecha, el modelo propuesto permite estimar el número de hospitalizaciones con nueve días de antelación. Ello lo convierte en una herramienta útil para prever con cierta anticipación la presión hospitalaria que el sistema sanitario tendrá que soportar como consecuencia de la enfermedad.

Potential link between SARS-CoV-2 and Kawasaki disease: importance of dentists for the diagnosis

Abstract: Kawasaki disease (KD) is a vasculitis with predilection for coronary arteries. Due to a lack of reliable confirmatory laboratory tests, the diagnosis of KD is based on a characteristic pattern of clinical findings that appear in a typical temporal sequence. The diagnostic criteria have been periodically modified and the American Heart Association has proposed the most recent guidelines for its diagnosis. However, patients may have incomplete or atypical forms of KD and diagnosis can often be difficult. Because oropharyngeal manifestations are a common and important feature for diagnosing KD and recent studies have hypothesized a possible association between KD and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in this review we highlight the importance of dentists in the diagnosis of KD and its potential association with SARS-CoV-2.

Analysis of dentistry youtube videos related to COVID-19

Abstract This study aimed to analyze the videos available on YouTube related to dentistry and the novel coronavirus (COVID-19), as there is no such analysis in the existing literature. The terms "dental" and "COVID-19" were searched on YouTube on May 9, 2020. The top 116 English-language videos with at least 300 views were analyzed by two observers. Data was saved for each video, including target audience, source, country of origin, content, number of views, time watched, average views, duration, like/dislike ratio, and usefulness. Total video information and quality index (VIQI) scores were calculated, consisting of flow, information, accuracy, quality, and precision indices. Non-parametric tests were used for analysis. The analyzed videos were viewed 375,000 times and totaled 20 h of content. Most videos were uploaded by dentists (45.7%), originated from the United States (79.3%), and contained information targeted towards patients (48.3%). Nearly half of the videos (47.4%) were moderately useful. For the usefulness of the videos, statistically significant differences were found for all indices as well as total VIQI scores. A comparison of the indices according to the relevance of the videos showed statistically significant differences in the videos' information and precision indices and total VIQI scores. The results of this study showed that dentistry YouTube videos related to COVID-19 had high view numbers; however, the videos were generally moderate in quality and usefulness.

Resumo Este estudo teve como objetivo analisar os vídeos disponíveis no YouTube relacionados à odontologia e ao novo coronavírus (COVID-19), visto que não há tal análise na literatura existente. Os termos "dental" e "COVID-19" foram pesquisados no YouTube em 9 de maio de 2020. Os 116 principais vídeos em inglês, com pelo menos 300 visualizações, foram analisados por dois observadores. Os dados foram salvos para cada vídeo, incluindo público-alvo, fonte, país de origem, conteúdo, número de visualizações, tempo assistido, média de visualizações, duração, proporção de gostar/não gostar e utilidade. As pontuações do índice total de informação e qualidade de vídeo (VIQI) foram calculadas, consistindo em índices de fluxo, informação, exatidão, qualidade e precisão. Testes não paramétricos foram usados para análise. Os vídeos analisados ​​foram assistidos 375 mil vezes e totalizaram 20 h de conteúdo. A maioria dos vídeos foi enviada por dentistas (45,7%), com origem nos Estados Unidos (79,3%) e com informações direcionadas aos pacientes (48,3%). Quase metade dos vídeos (47,4%) foram moderadamente úteis. Para a utilidade dos vídeos, foram encontradas diferenças estatisticamente significantes para todos os índices, bem como para os escores totais do VIQI. Uma comparação dos índices de acordo com a relevância dos vídeos mostrou diferenças estatisticamente significativas nas informações dos vídeos e nos índices de precisão e nas pontuações totais do VIQI. Os resultados deste estudo mostraram que os vídeos de odontologia no YouTube relacionados à COVID-19 tiveram um alto número de visualizações; no entanto, os vídeos eram geralmente moderados em qualidade e utilidade.

In-depth morphological evaluation of tooth anatomic lengths with root canal configurations using cone beam computed tomography in North American population

Abstract Objective This study aimed to assess the association between tooth size and root canal morphology by using CBCT analysis. Methodology In this retrospective study, tooth anatomic lengths (crown and root lengths, buccolingual and mesiodistal dimensions) of 384 patients were assessed and correlated with Vertucci's root canal morphology classification. Data was analyzed for gender-related differences using the independent sample t-test, ANOVA, and the Pearson's correlation for a possible relation between anatomic lengths and canal morphology. Results The maxillary first and second premolars showed a greater predilection for Type IV and II variants, respectively, while the mandibular first premolar showed a greater predilection for Type II canal system. The root canal system of the mandibular second premolar showed maximal diversity (47% Type I, 30% Type II, and 20% Type III). The dimensions were greater in men regardless of tooth type. The most significant relation (p<0.05) between the anatomic size and canal morphology was observed in the maxillary first premolars, followed by the mandibular canines (buccolingual dimension) and the lower second premolars (crown length). Negative correlations existed between the crown length and the patient's age for the anterior teeth and mandibular second premolar (r=−0.2, p<0.01). Conclusions The most common canal formation for anterior teeth was the Type I. The anatomic lengths had the strongest influence on the canal configuration of the maxillary first premolar, with Type IV being the most common root canal system. The mandibular second premolars showed maximal diversity in the canal classification terms and had a significant correlation with their crown lengths. Clinical Relevance The complex relationship between the canal morphology and anatomic tooth sizes need meticulous awareness and recognition during endodontic procedures, in conjunction with the demographic variabilities.

Nutritional profile of ultra-processed foods consumed by children in Rio de Janeiro / Perfil nutricional de alimentos ultraprocessados consumidos por crianças no Rio de Janeiro

ABSTRACT OBJECTIVE To analyze the nutritional composition of ultra-processed foods consumed by children that attend basic health units. METHODS This is a cross-sectional study with a representative probabilistic sample of 536 children aged between 6 and 59 months treated at a health unit in the city of Rio de Janeiro. Nutritional information was extracted from labels of the ultra-processed foods referred to in a 24-hour recall. The 351 foods mentioned were divided into 22 groups and 38 subgroups according to the type of product, and they were characterized according to the averages of the values for energy, total fats, saturated fats, trans fats and sodium in 100 grams of the product, in addition to presence, number, and type of "other sweeteners". The nutritional Profile Model of the Pan American Health Organization was applied for each food and for the average of nutrient content obtained for each group to examine the occurrence of critical nutrients excess. RESULTS Ultra-processed foods contained high energy value and high levels of total fats, saturated fats, trans fats, and sodium. Out of the total of ultra-processed foods, 66% presented excess of at least one critical nutrient, with emphasis on requeijões and ultra-processed cheeses, instant noodles, and industrialized and sausage-like meats, which presented 100% of foods with excess of total fats, saturated fats and sodium. Out of the 21 groups, the following exceeded the limit established by the Pan American Health Organization: for total fats, 10 groups; for saturated fats, 11; for trans fats, 3; and sodium, 13. Requeijões and ultra-processed cheeses; industrialized and sausage-like meats; and biscuits exceeded this limit in all parameters. Out of the set of ultra-processed foods analyzed, 13.4% contained "other sweeteners" (eight different types). CONCLUSIONS The ultra-processed foods analyzed presented unbalanced nutritional profile, and two thirds presented excess of at least one critical nutrient. Educational actions and regulatory measures are necessary to better inform the population and to discourage its consumption.

RESUMO OBJETIVO Analisar a composição nutricional dos alimentos ultraprocessados consumidos por crianças usuárias de unidades básicas de saúde. MÉTODOS Trata-se de estudo seccional com amostra probabilística representativa de 536 crianças de 6 a 59 meses de idade atendidas em uma unidade de saúde no município do Rio de Janeiro. Informações nutricionais foram extraídas dos rótulos dos alimentos ultraprocessados referidos em recordatório de 24 horas. Os 351 alimentos citados foram divididos em 22 grupos e 38 subgrupos de acordo com o tipo de produto e caracterizados segundo as médias dos valores encontrados para energia, gorduras totais, gorduras saturadas, gorduras trans e sódio em 100 gramas do produto, além de presença, número e tipo de "outros edulcorantes". Para examinar a ocorrência de excesso de nutrientes críticos, o Modelo de Perfil Nutricional da Organização Pan-Americana da Saúde foi aplicado para cada alimento e para a média dos teores de nutrientes obtida para cada grupo. RESULTADOS Os alimentos ultraprocessados consumidos continham alto valor energético e elevados teores de gorduras totais, gorduras saturadas, gorduras trans e sódio. Do total de alimentos ultraprocessados, 66% apresentaram excesso de pelo menos um nutriente crítico, com destaque para requeijões e queijos ultraprocessados, macarrões instantâneos e carnes industrializadas e embutidos, que apresentaram 100% dos alimentos com excesso de gorduras totais, de gorduras saturadas e de sódio. Dos 21 grupos, extrapolaram o limite estabelecido pela Organização Pan-Americana da Saúde: para gorduras totais, 10 grupos; para gorduras saturadas, 11; para gorduras trans, 3; e para sódio, 13. Requeijões e queijos ultraprocessados; carnes industrializadas e embutidos; e biscoitos superaram esse limite em todos os parâmetros. Do conjunto de alimentos ultraprocessados analisados, 13,4% continham "outros edulcorantes" (oito diferentes tipos). CONCLUSÕES Os AUP analisados apresentaram perfil nutricional desequilibrado e dois terços apresentaram excesso de pelo menos um nutriente crítico. Fazem-se necessárias ações educativas e medidas regulatórias para melhor informar a população e desencorajar o seu consumo.

Differences in Proteomic Profiles Between Caries Free and Caries Affected Children

Abstract Objective: To determine if there are differences in protein profiles in saliva depending if children of caries-free versus caries affected. Material and Methods: A cohort of 91 children with ages between 6 and 19 years, along clinical status of caries experience. Protein profiles in saliva were determined using electrophoresis and the calculation of the percentage of a specific band at a specific molecular weight in relationship to the total protein in that sample (% of total) using molecular weight standards. This quantification was repeated for each protein band across a range of molecular weights for each sample. Chi-square, Fisher's exact, and Student t-tests were used to compare the distributions between caries-free and caries affected children (α=0.05). Results: Histatin was more likely to be non-detectable or reduced in caries-free children (OR=7.56; 95% CI 1.62-35.13) and these children had on average one less gel band detected by the assay we used. Conclusion: We have found differences in proteins between caries affected and caries-free children, suggesting that this line of investigation holds the promise of providing new tools for caries management.

COVID-19-Related Challenges in Dental Education: Experiences From Brazil, the USA, and Australia

Abstract Objective: To describe and compare how three dental schools from different countries (Australia, Brazil, and the USA) have managed experiences in dental education during the COVID-19 crisis. Material and Methods: It is a descriptive study reporting the experience that three distinct dental schools faced during the COVID-19 pandemic. They represent countries that adopted different measures to tackle the pandemic and were undergoing different stages of the disease. Results: After the WHO declared the COVID-19 pandemic, the Federal University of Paraíba suspended all on-site teaching, research, and service activities. For the return to teaching activities, the use of information and communications technology resources for distance learning was recommended. At the School of Dental Medicine (University of Pittsburgh), all research activities were suspended or, otherwise, could not be interrupted because of the employment of unique materials or supplies. When the pandemic started, Australia was one of the first countries to introduce strong regulations related to social distancing, travel restrictions, testing and tracking of infected patients. As such, the universities started to be closed from mid-March, cancelling all clinical and pre-clinical activities, maintaining online theoretical activities, such as seminars, lectures, and journal clubs. Conclusion: Numerous and critical difficulties have arisen as a result of the pandemic for individuals, communities and institutions that will have long-lasting effects. Our students face disruption to their education and career; our professional colleagues will be challenged rebuilding their practices, while staff at all Dental Schools are experiencing various hardships.

Primary headaches interfere with the efficacy of temporomandibular disorders management

OBJECTIVES: This cross-sectional study aimed to evaluate the influence of Primary Headache (PH) on efficacy of a Temporomandibular Disorders (TMD) conservative therapy and its association with the presence of self-reported parafunctional habits. SAMPLE AND METHODS: Sample was composed of 400 medical records, divided into four groups: I) Muscular TMD (n=64); II) Muscular TMD+PH (n=48); III) Muscular TMD+Articular TMD (n=173); IV) Muscular TMD+Articular TMD+PH (n=115). All groups had undergone a TMD therapy for three months with a stabilization appliance and counseling for habits and behavioral changes, with no specific headache management. Current pain intensity and existence or not of self-reported bruxism were assessed. Repeated measures ANOVA and Chi-Square test followed by Odds were used for statistical analysis, with a significance level of 5%. RESULTS: results of this study showed that: (1) A conservative therapy with stabilization appliance and counseling for habits and behavioral changes was effective in the TMD pain relief; (2) Groups with an additional diagnosis of PH had worsened the pain improvement significantly; and (3) no association between the presence of self-reported bruxism and PH was found. CONCLUSIONS: this study could elucidate the important effect that headache may have on the TMD management. .

Oral potentially malignant disorders in a large dental population

Objectives Oral cancer (OC) may be preceded by clinically evident oral potentially malignant disorders (OPMDs). Oral carcinogenesis is a multistep process that begins as epithelial hyperplasia and progresses to oral epithelial dysplasia and finally to fully malignant phenotypes. The aim of our study was to estimate the prevalence of OPMDs in a large population of dental patients. Methods Patients were seen in the Oral Diagnosis and Oral Medicine clinics at Boston University Henry M. Goldman School of Dental Medicine between July 2013 and February 2014 and received a comprehensive oral examination to identify any possible mucosal lesions. Patients with a suspected OPMD (submucous fibrosis, oral lichen planus, leukoplakia and erythroplakia) that did not resolve in 2–3 weeks received a biopsy for definitive diagnosis. Logistic regression models were used to explore the relationship between OPMDs and associated risk factors. Results A total of 3,142 patients received a comprehensive oral examination [median age: 43 (range: 18–97); 54.3% females]. Among these, 4.5% had an oral mucosal lesion with 0.9% being an OPMD (one submucous fibrosis, three epithelial dysplasias, fourteen with hyperkeratosis/epithelial hyperplasia and nine with oral lichen planus). Males and current smokers were associated with higher odds of having OPMD (OR 1.7, 95% CI 0.8–3.8; OR 1.9, 95%CI 0.8–4.1). Increasing age was associated with having OPMDs (p<0.01). Conclusion Optimal oral visual screening for OC remains a simple and essential tool to identify any suspicious lesions and potentially increase survival. Although OPMDs were rare, our results confirm the importance of a thorough chairside screening by dentists and dental students to detect any mucosal changes. .

Tratamento endodôntico em sessäo única / Endodontic treatment in single section

O presente estudo avalia a situaçäo do tratamento endodôntico em sessäo única de dentes necrosados com lesäo apical nas Universidades dos Estados Unidos da América. Foi enviada a cada Universidade uma carta explicativa com um questionário contendo 8 perguntas objetivas e 1 pergunta subjetiva. Totlizaram 61 cartas enviadas e 47 respondidas. A partir dos resultados concluímos que o tema ainda gera certa polêmica, porém a maior parte das Universidades pratica o tratamento de dentes sem vitalidade pulpar e com lesäo periapical em sessäo única

A interface selante-esmalte em fissuras de pré-molares empregando a técnica invasiva e näo invasiva: estudo ao microscópio eletrônico de varredura / Sealant-enamel interface in pre-molars fissures with invasive and non-invasive techniques. A scanning electron microscopy study

No presente trabalho, empregando a técnica de microscopia eletrônica de varredura, foram estudadas as características de interface esmalte-selante em dentes pré-molares submetida a técnica invasiva ou näo invasiva. Os dentes tratados foram extraídos (por indicaçäo clínica) e mantidos em soluçäo de alcool a 70 por cento, procedendo-se em seguida fraturas longitudinais no sentido vestibulo-lingual ou tratamento em soluçäo de ácido nítrico a 20 por cento para a obtençäo de amostras. Todas as amostras foram desidratadas em série crescente de álcoois, montadas em bases metálicas para a cobertura de ions de ouro em aparelho "Ions Sputter" e examinadas em microscopio eletrônico de varredura "Stereoscan" 240, Cambridge. De acordo com os resultados obtidos na presente pesquisa podemos concluir que: 1) As peças fraturadas no sentido vestíbulo-lingual e examinadas ao microscópio eletrônico de varredura revelaram nitidamente os detalhes de interface esmalte-selante das diferentes regiöes analisadas. 2) As partículas inorgânicas da matriz do selante Sealite näo interferem na penetrabilidade e no embricamento do selante com a superfície do esmalte. 3) Observou-se a presença de microprojeçöes resinosas "tags" em todas as amostras de selantes preparadas pela técnica invasiva evidenciando um comprimento que variou de 4,239 a 13,953 micrometros. 4) A análise de variância revelou que existe uma diferença estatisticamente significante no comprimento das microprojeçöes do selante quando comparadas as regiöes cavo-superficial, superior, média, inferior e fundo da fissura na técnica invasiva, com maiores valores na regiäo do fundo. 5) A análise de variância revelou que existe uma diferença estatisticamente significante no comprimento das microprojeçöes do selante quando comparadas às regiöes cavo-superficial com superior, média e inferior da fissura e näo significante entre as comparaçöes das regiöes superior, média e inferior na técnica näo invasiva, com maiores valores na regiäo cavo-superficial. 6) Tanto nas técnicas invasiva como nas näo invasiva, apresentaram projeçöes resinosas de formas predominantemente cônicas e de tamanhos variáveis