RESUMO
No disponible
Assuntos
Animais , Masculino , Feminino , Imunização/métodos , Imunização/veterinária , Rinite Alérgica/imunologia , Rinite Alérgica/veterinária , Asma/imunologia , Asma/veterinária , Phodopus/imunologia , Animais Domésticos/imunologia , Hipersensibilidade/imunologia , Hipersensibilidade/veterináriaRESUMO
No disponible
Assuntos
Animais , Masculino , Feminino , Hipersensibilidade/complicações , Hipersensibilidade/imunologia , Hipersensibilidade/veterinária , Rinite/imunologia , Rinite/veterinária , Asma/complicações , Asma/imunologia , Biomarcadores/análise , Phodopus/imunologiaRESUMO
No disponible
Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Animais de Estimação/imunologia , Phodopus/imunologia , Alergia e Imunologia , Hipersensibilidade/complicações , Hipersensibilidade/diagnóstico , Hipersensibilidade/imunologia , Conjuntivite/complicações , Conjuntivite/imunologia , Conjuntivite Alérgica/imunologia , Mesocricetus/imunologia , Obstrução Nasal/complicações , Obstrução Nasal/imunologia , Rinite/complicações , Rinite/imunologiaRESUMO
No disponible
Several weeks of short day photoperiod (SD) exposure promote a dramatic decrease of white adipose tissue (WAT) mass in Siberian hamsters(Phodopus sungorus sungorus). This slimming effect is accompanied by changes in the adipocyte responsiveness to adrenergic stimulation that are still under debate. We investigated whether possible changes in the antilipolytic responses, and/or lipogenic activities could be involved in such lipid deposition/mobilisation imbalance. Male Siberian hamsters were exposed for 11 weeks to SD or long day photoperiod and basal or stimulated lipolytic and lipogenic activities were measured on white adipocytes. As expected, the body mass of SD-animals was decreased. Besides a slight reduction in the basal lipolysis and in the maximal response to dibutyryl-cAMP, the responses to adrenergic and non-adrenergic lipolytic agents (forskolin, adenosine deaminase) were similar in both groups. Fat mass loss was likely not resulting from changes in the lipolytic responses of adipocytes to biogenic amines (e.g. octopamine), which were unaltered, or to a direct lipolytic stimulation by melatonin or histamine, which were inactive. Antilipolytic responses to insulin or tyramine were slightly decreased in SD-adipocytes. Basal or insulin-stimulated lipid accumulation in WAT, measured by glucose incorporation into lipids, did not change after SD-exposure. However, a significant decrease in the lipoprotein lipase activity was observed in the WAT of SDanimals. Despite the observed changes, the weight loss of SD-exposed Siberian hamsters was likely not resulting only from impaired antilipolytic orde novo lipogenic activities in white adipocytes, but either from other dramatic changes occurring during seasonal photoperiod-sensitive body weight regulation (AU)