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Introduction: Association between Motor Neuron Disease (MND) and neoplastic processes is rarely described. It is unclear whether MND occurs as a paraneoplastic syndrome. Methods: We retrospectively analysed 35 patients with MND followed in our Hospital from January 2013 to December 2016. Results: A neoplastic process was found in four patients. All of them had definite clinical and electromyographic criteria supporting MND according to standard Awaji criteria. Results: Onconeuronal antibodies were positive in two patients (anti-Yo and anti-PNMA2). The types of tumour were variable: two breast cancers, one lung cancer and one thyroid Hürthle cell neoplasm. Discussion: In our cohort, 11.4% of MND patients were diagnosed with a neoplastic process being a rather high frequency of co-occurrence. Treating the neoplastic process may potentially halt or reverse the progression of MND. (AU)
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Humanos , Neurônios Motores , Processos Neoplásicos , Doenças do Sistema Nervoso , DoençaRESUMO
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Humanos , Feminino , Neoplasias da Mama/genética , Predisposição Genética para Doença , Processos Neoplásicos , Vírus Oncogênicos , Cloridrato de Raloxifeno/farmacocinética , Tamoxifeno/farmacocinética , Fatores de RiscoRESUMO
El angiomixoma agresivo es una neoplasia pocofrecuente, que suele afectar a la región perineal ypelvis, con capacidad infiltrativa local y frecuentesrecurrencias; el tratamiento de elección es laexéresis quirúrgica completa.Presentamos un caso de angiomixoma agresivolocalizado en región pelviperineal, realizando unarevisión de las características clinicopatológicas y elmanejo de estos pacientes.Es importante considerar el diagnóstico deangiomixoma agresivo en pacientes con masa enregión perineopélvica
Aggressive angiomyxoma is a rare tumor thatusually involves the pelvic and perineal regions.These locally infiltrative tumors are associated with a high recurrence rate. The treatment of choiceis radical surgical excision.We report a case of aggressive angiomyxoma ofthe female pelvis and perineum and review theclinical and pathologic characteristics of this entity,as well as the management of these patients.Any perineal-pelvic tumor should be evaluatedas a potentially aggressive angiomyxoma
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Humanos , Feminino , Adulto , Mixoma/patologia , Neoplasias Pélvicas/patologia , Mixoma/cirurgia , Processos Neoplásicos , Neoplasias Pélvicas/cirurgia , Diagnóstico DiferencialRESUMO
Objetivo:Evaluar la utilizdad del bloqueo del plexo braquial en eltratamiento del dolor intenso oncológico.Método:Evaluamos en 6 pacientes con metástasis óseas delmiembro superior la efectividad de un bloqueo continuo delplexo braquial.Resultados:Todos los pacientes del estudio tuvieron una evoluciónfavorable y un incremento en la analgesia con el tratamientosin que se produjeran efectos adversos.Conclusiones:La analgesia continua del plexo braquial es un métodoefectivo para el control del dolor del miembro superior pormetástasis
Objective:To assess the effectiveness of brachial plexus blockadefor the management of severe cancer pain.Method:In six patients with upper limb bone metastases, we assessedthe effectiveness of continuous blockade of thebrachial plexus.Results:All the study patients had a favorable evolution andanalgesia increased with the treatment, without side effects.Conclusions:Continuous analgesia of the brachial plexus is an effectivemethod for the management of upper limb pain causedby metastases
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Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Humanos , Analgesia/métodos , Bloqueio Nervoso/métodos , Plexo Braquial , Processos Neoplásicos , Braço/patologia , Metástase Neoplásica , Neoplasias Ósseas/complicaçõesRESUMO
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