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1.
Int. microbiol ; 14(4): 225-233, dic. 2011. ilus
Artigo em Inglês | IBECS | ID: ibc-102987

RESUMO

Wine can contain trace amounts of ethyl carbamate (EC), a carcinogen formed when ethanol reacts with carbamyl compounds such as citrulline. EC is produced from arginine by lactic acid bacteria (LAB), e.g., Lactobacillus and Pediococcus. Although the amounts of EC in wine are usually negligible, over the last few years there has been a slight but steady increase, as climate change has increased temperatures and alcohol levels have become proportionately higher, both of which favor EC formation. In this study, resting cells of LAB were used to evaluate the effects of ethanol, glucose, malic acid, and low pH on the ability of non-oenococcal strains of these bacteria to degrade arginine and excrete citrulline. Malic acid was found to clearly inhibit arginine consumption in all strains. The relation between citrulline produced and arginine consumed was clearly higher in the presence of ethanol (10-12%) and at low pH (3.0), which is consistent with both the decreased amount of ornithine produced from arginine and the reduction in arginine degradation. In L. brevis and L. buchneri strains isolated from wine and beer, respectively, the synthesis of citrulline from arginine was highest (AU)


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Assuntos
Uretana/isolamento & purificação , Arginina/biossíntese , Ácido Láctico/biossíntese , Vinho/microbiologia , Lactobacillus/enzimologia , Citrulina , Pediococcus/isolamento & purificação
2.
Rev. Rol enferm ; 32(5): 377-382, mayo 2009. ilus
Artigo em Espanhol | IBECS | ID: ibc-76164

RESUMO

Se valora el comportamiento de los apósitos de espuma de poliuretano Skinfoam®, en el tratamiento de úlceras por presión y úlceras vasculares de moderada a altamente exudativas, mediante un estudio observacional de series de casos clínicos, multicéntrico, prospectivo y abierto. La duración del estudio fue de hasta 20 cambios de apósito o hasta la curación. En la visita inicial se anotaron los datos del paciente, incluyendo una valoración de las características de la lesión; en las visitas de cambio de apósito se registró la evolución de la lesión y de los cambios de apósito, y en la visita final se evaluaron las características finales de la lesión así como la valoración global del comportamiento del apósito. Se incluyeron 185 pacientes con una edad media de 75,5 años. Al final del estudio un 44,32% de los mismos no presentaba ninguna úlcera mientras que en los restantes constatamos una disminución importante del tamaño de la lesión, aumentando considerablemente el tejido de epitelización. La piel perilesional mejora en todos los aspectos y disminuye de forma estadísticamente significativa el eritema y el eczema. La fuga de exudado llegó a ser nula en el último cambio de apósito. Los pacientes manifiestan ausencia de dolor antes de finalizar el estudio. El grado de satisfacción global indicó bueno, muy bueno o excelente por el 95,15% de los profesionales y el 100% de los pacientes volvería a utilizarlo. Se concluye que el apósito en estudio Skinfoam® es efectivo en el tratamiento de las úlceras por presión y úlceras vasculares altamente exudativas, incluso en terapia compresiva, pudiendo ser el de elección(AU)


The authors evaluate the behavior of Skinfoam® Polyurethane Foam Dre-ssings in the treatment of bed sores and vascular ulcers having a moderate to high exudation level by means of a multi-centric, prospective, open, observational study of a series of clinical cases. The length of this study was up to 20 dressing changes or until the patient was cured. During the first visit with patients, the personnel recorded patient data including an evaluation of the characteristics of patient’s lesion; during visits to change dressings, the medical personnel recorded the evolution of the lesion and dressing changes; during the final visit, the medical personnel evaluated the final characteristics of the lesion as well as a global evaluation of the behavior of the dressing. This study included 185 patients who had an average age of 75.5. At the end of this study, 44.32% of these patients did not have any signs of an ulcer while among the other patients, the medical team noted an important decrease in the size of their lesions, with a considerable increase of tissue epithelization. The perilesional skin showed improvement in all aspects and erythema and eczema diminished in a statistically significant manner. The presence of exudation was null when the final dressing change occurred. Patients manifested a lack of pain before the end of this study. 85.15% of the professionals indicated a global satisfaction level of good, very good or excellent while 100% of the patients stated they would use his dressing again. The authors conclude that the dressing under study is effective in the treatment of bed sores and high exudation vascular ulcers; even in cases involving compressive therapy, this dressing could be the one chosen for application(AU)


Assuntos
Humanos , Masculino , Feminino , Úlcera/terapia , Uretana/uso terapêutico , Bandagens , /enfermagem , Hipersensibilidade a Drogas/epidemiologia , Hipersensibilidade a Drogas/enfermagem , Lesão por Pressão/enfermagem , Lesão por Pressão/prevenção & controle , Cicatrização/fisiologia , Infecção dos Ferimentos/epidemiologia , Ferimentos e Lesões/epidemiologia , Ferimentos e Lesões/enfermagem , Ferimentos não Penetrantes/enfermagem , Sinais e Sintomas , Análise de Variância
3.
Ars pharm ; 41(2): 159-165, abr. 2000. ilus
Artigo em Es | IBECS | ID: ibc-23451

RESUMO

La formación e identificación del carbamato de etilo ha conducido a numerosos estudios para entender mejor su formación y su posterior identificación y cuantificación. En esta revisión sintetizamos lo que ha sido aportado en la literatura que se ha publicado en este tema en las últimas décadas. Se realiza un especial interés en la formación, los precursores y los métodos analíticos de identificación y cuantificación del carbamato de etilo (AU)


Assuntos
Humanos , Uretana/análise , Bebidas Alcoólicas/análise , Uretana/metabolismo , Uretana/química , Dietil Pirocarbonato/análise , Grão Comestível/química , Queijo/análise , Iogurte/análise , Pão/análise , Óleo de Soja/química
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