Fracturas de tibia por estrés y hallazgos patológicos asociados en reclutas / Tibial stress fractures and associated pathologies in military recruits

Introducción: Las fracturas de tibia por estrés son un cuadro muy frecuente en el personal militar recién incorporado. Nuestro objetivo fue demostrar que existe una asociación entre fracturas por estrés y otros hallazgos patológicos. materiales y métodos: Se evaluaron retrospectivamente 42 fracturas por estrés en 34 pacientes, entre noviembre de 2012 y septiembre de 2014. Todos se habían incorporado recientemente al Ejército Argentino y consultaron por cuadros dolorosos en la tibia. Se realizó el diagnóstico clínico y centellográfico de fractura por estrés. Se documentaron datos filiatorios, hallazgos patológicos asociados y factores de riesgo. Los criterios de inclusión fueron: reciente incorporación, mismo entrenamiento, edad 16-23 años. Se excluyó a pacientes con traumatismos, enfermedad tumoral o centellograma negativo, y a los simuladores. Resultados: Se evaluaron 42 fracturas por estrés en 34 pacientes (14 hombres y 20 mujeres). La edad promedio era de 20 años. No hubo diferencias significativas en el número de lesiones respecto al miembro afectado. El 64,7% tenía hallazgos patológicos asociados (mujeres 73%, hombres 27%). El 80% de las mujeres y el 43% de los hombres tenían un hallazgo patológico asociado. Se detectaron diversos hallazgos patológicos asociados con desejes de miembros inferiores en varo y en valgo, los primeros fueron los que más se asociaron con fracturas. Conclusiones: La tasa de asociación con hallazgos patológicos en los miembros inferiores fue alta, con predominio de los desejes en varo. Las mujeres con fracturas por estrés tenían más hallazgos patológicos asociados que los hombres. Nivel de Evidencia: IV

Introduction: Tibial stress fractures are a very common condition in military recruits. Our objective is to demonstrate that stress fractures are associated with other pathologies. materials and methods: 42 stress fractures in 34 patients were retrospectively evaluated. Every patient had recently joined the Argentine Army and consulted for painful symptoms in the tibia. A clinical and scintigraphic diagnosis of stress fracture was made. Patient data, associated pathologies, and risk factors were documented. Inclusion criteria: recent incorporation, same training, age between 16 and 23 years. Trauma, simulators, tumoral pathology, and cases with negative scintigraphy were excluded. Results: We studied 42 stress fractures in 34 patients, 14 were men and 20 were women. The average age was 20 years. There were no significant differences in the number of injuries regarding the affected limb. 64.7% had associated pathologies, 73% in women and 27 % in men. Among the women with stress fractures, 80% had associated pathologies, compared to 43% for men. Different pathologies were found with lower limb varus and valgus imbalances. Varus was the most associated with fractures. Conclusions: A high rate of associated pathologies was found in patients with tibial stress fractures with a predominance of lower limb varus imbalances. Associated pathologies were more likely to be found in women with stress fractures than in men. Level of Evidence: IV

Treatment of Chondral Lesions in the Knee / Tratamento das lesões condrais no joelho

Abstract Articular cartilage injuries are common and lead to early joint deterioration and osteoarthritis. Articular cartilage repair techniques aim at forming a cartilaginous neo-tissue to support the articular load and prevent progressive degeneration. Several techniques are available for this purpose, such as microfracture and chondrocyte transplantation. However, the procedural outcome is often fibrocartilage, which does not have the same mechanical resistance as cartilaginous tissue. Procedures with autologous osteochondral graft have a morbidity risk, and tissue availability limits their use. As such, larger lesions undergo osteochondral transplantation using fresh or frozen grafts. New techniques using minced or particulate cartilage fragments or mesenchymal stem cells are promising. This paper aims to update the procedures for treating chondral lesions of the knee.

Resumo As lesões da cartilagem articular são comuns e levam à deterioração precoce da articulação e ao desenvolvimento da osteoartrite. As técnicas de reparo da cartilagem articular visam a formação de um neo-tecido cartilaginoso capaz de suportar carga articular e evitar a progressão da degeneração. Há várias técnicas disponíveis para esse fim, como a microfratura e o transplante de condrócitos. Entretanto muitas vezes o desfecho do procedimento é a formação de fibrocartilagem, que não possui a mesma resistência mecânica do tecido cartilaginoso. Em outros procedimentos, nos quais é realizado enxerto osteocondral autólogo, há risco de morbidade associada ao procedimento, além da disponibilidade limitada de tecido. Por esse motivo, o transplante osteocondral, utilizando enxertos a fresco ou congelados tem sido utilizado para lesões de maior volume. Por fim, novas técnicas utilizando fragmentos de cartilagem picada ou particulada, assim como o uso de células tronco mesenquimais se apresentam como promissores. O objetivo desse artigo é realizar uma atualização dos procedimentos para tratamento das lesões condrais do joelho.

Humerus Diaphyseal Stress Fracture in a Teenage Tennis Athlete: Case Report / Fratura por estresse diafisária do úmero em atleta de tênis adolescente: Relato de caso

Abstract A teenage male tennis player had chronic pain in his dominant arm during tennis practice. Magnetic resonance imaging (MRI) suggested humerus diaphyseal stress injury. After 4 weeks, he became asymptomatic and resumed playing. However, pain recurred after 3 days. A new MRI revealed a diaphyseal undisplaced humerus fracture and significant bone marrow edema. The patient remained in rest for 4 weeks. After that, strengthening exercises were introduced and return to training was allowed after 12 weeks. Even if asymptomatic, we suggest that these patients should not return to play before 12 weeks, depending on the physical exam and imaging findings.

Resumo Um tenista adolescente tinha dor crônica no braço dominante durante os treinos de tênis. A ressonância magnética (RM) sugeriu lesão por estresse na diáfise do úmero. Depois de 4 semanas, ele se tornou assintomático e voltou a jogar. No entanto, houve recidiva da dor após 3 dias. A nova RM revelou fratura diafisária não desviada do úmero e edema significativo da medula óssea. O paciente ficou em repouso por 4 semanas. Depois disso, exercícios de fortalecimento foram introduzidos e o retorno aos treinamentos foi permitido após 12 semanas. Mesmo que assintomáticos, sugerimos que esses pacientes não voltem a jogar antes das 12 semanas, dependendo dos exames físicos e dos achados por imagem.

Treatment of Hip Wave Lesion Using Reverse Microfracture: A Retrospective Clinical Study / Tratamento da lesão em onda do quadril através da microfratura reversa: Estudo clínico retrospectivo

Abstract Objective The present study aims to evaluate the treatment of hip wave lesion using reverse microfracture, which is a simple and cheap surgical procedure. Methods We retrospectively analyzed 19 patients with acetabular wave lesion treated with reverse microfracture. The patients were assessed by magnetic nuclear resonance imaging (MRI) at the time of diagnosis and 6 months after the surgery and functionally evaluated using the Harris Hip Score (HHS) and the visual analogue scale (VAS) for pain in the preoperative period, and 3 and 6 months after the surgery. Results The statistical data showed a significant improvement in HHS and VAS 6 months after the surgery. Six months after the surgery, the MRI revealed that the area subjected to reverse microfracture presented cartilage with the same visual characteristics observed in areas with no chondral injury. Conclusion We conclude that the reverse microfracture proved to be an effective, reproducible method for the treatment of wave lesion.

Resumo Objetivo Avaliar o tratamento desta lesão, através da microfratura reversa, que é um procedimento simples e sem aumento de insumos na cirurgia. Métodos Foram analisados retrospectivamente 19 pacientes submetidos a tratamento da lesão em onda no acetábulo, através da microfratura reversa. Utilizamos a ressonância nuclear magnética (RNM) no momento do diagnóstico e 6 meses após a cirurgia, avaliação funcional pelo Harris Hip Score (HHS) e escala visual e analógica (EVA) da dor no pré-operatório, e 3 e 6 meses após a cirurgia. Resultadoos dados estatísticos mostraram melhora significativa do HHS e EVA da dor após 6 meses da cirurgia. A RNM após 6 meses da cirurgia mostrou que na área que foi submetida à microfratura reversa, a cartilagem se apresentou com as mesmas características visuais que nas áreas sem lesão condral. Conclusão Concluímos que a microfratura reversa se mostrou eficaz e reprodutível no tratamento da lesão em onda.

Isokinetic ankle muscle strength is reduced in recreational runners with medial tibial stress syndrome and is not associated with pain

Abstract Aim: The purpose of this study was to investigate the strength and ratios of the plantar flexors and ankle dorsiflexors in recreational runners with medial tibial stress syndrome and to assess the association between muscle strength and the level of pain in this population. Methods: Two groups (control and medial tibial stress syndrome) of eighteen runners each participated in this cross-sectional study. Isokinetic dynamometry was used to evaluate muscle strength, and for the analysis, the normalized isokinetic peak torque controlled by gender was used. Results: The medial tibial stress syndrome group showed lower normalized isokinetic peak torque in the dorsiflexors in the concentric (p = 0.008) eccentric (p = 0.011) contraction, as well as a lower plantar flexor, normalized isokinetic peak torque in the concentric (p = 0.001) and eccentric (p = 0.02) when compared to the control group. However, there was no difference in the normalized isokinetic peak torque ratio representative of the stance (p = 0.62) and swing phase (p = 0.16), and the level of pain was not correlated with the strength concentric (p = 0.32) and eccentric (p = 0.621) of plantar flexors, nor to the concentric (p = 0.21) and eccentric of dorsiflexors (p = 0.54). Conclusion: Recreational runners with MTSS showed decreased muscle strength in the sagittal plane of the ankle, no correlation with the level of pain, and no changing the ratio between plantar flexors and dorsiflexors.

Triathlete with Multiple Stress Fractures in the Lower Limbs: Case Report and Literature Review / Triatleta com múltiplas fraturas por estresse nos membros inferiores: Relato de um caso e revisão da literatura

Abstract Recurrent stress fractures rarely affect the same athlete. We present the case of a female triathlete who suffered multiple stress fractures in both tibias, the right fibula, and the left femoral neck. Conservative treatment was instituted in all episodes, with rest, reduced training load, and physical therapy rehabilitation. The relative energy deficiency in sport syndrome, along with an eating disorder, training overload, and osteopenia, was identified as a risk factor. Although rare, multiple stress fractures can occur in female triathletes. These patients must be screened for risk factors associated with biomechanics, nutrition, and training to develop an effective prevention and treatment program.

Resumo Fraturas por estresse recorrentes num mesmo atleta são raras. Apresentamos o caso de uma triatleta que sofreu múltiplas fraturas por estresse na tíbia bilateral, na fíbula direita e no colo femoral esquerdo. O tratamento conservador foi instituído em todos os episódios, com repouso, redução da carga de treino e reabilitação fisioterápica. Foi identificada como fator de risco a síndrome da deficiência energética relativa no esporte, com distúrbio alimentar, sobrecarga de treino e osteopenia. Mesmo que seja raro, múltiplas fraturas por estresse podem ocorrer em mulheres triatletas, nas quais é importante avaliar os fatores de risco associados à biomecânica, nutrição e ao treinamento para arquitetar um programa de prevenção e tratamento efetivos.

Repetitive stress fracture: a warning sign of genetic susceptibility to fracture? A case report of a heterozygous variant in SERPINF1

SUMMARY The occurrence of fractures in young individuals is frequently overlooked by physicians, especially when associated with exercise or trauma. Nevertheless, multiple fractures should always be investigated since underlying conditions can predispose to such events. We describe here the case of a young, healthy woman who sustained multiple fractures in the lower limbs, which were initially considered to be "stress fractures". Further investigation, including a panel of genes associated with osteogenesis imperfecta, revealed that the patient is a heterozygous carrier of a SERPINF1 variant. According to criteria recommended by the American College of Medical Genetics and Genomics and the Association for Molecular Pathology, this variant is classified as likely benign (PM2, PP3, PP4, BP1, and BP4). The patient's mother and brother were also asymptomatic carriers of the variant and had sustained previous minor fractures. The patient had normal biochemical profile and bone density. This condition has been rarely described and is not associated with low bone mineral density or altered bone turnover markers. This case highlights the importance of investigating multiple fractures in young patients who are otherwise healthy since these may be a warning sign of rare genetic conditions associated with fragility fractures.

Osteosíntesis en una fractura por estrés del pubis. Reporte de un caso y revisión de la bibliografía / Osteosynthesis in a pubic stress fracture. Case report and literature review

La fractura por estrés del pubis es un cuadro poco frecuente, se ha descrito en corredores de larga distancia y reclutas militares. Se han publicado 193 casos que fueron tratados de forma conservadora. El objetivo de este artículo es presentar un caso resuelto de manera alternativa, analizar los casos ya publicados, las enfermedades asociadas, el diagnóstico y el tratamiento. Se presenta el caso de una paciente añosa, deportista, con fractura por estrés del pubis, que no respondió al tratamiento conservador y fue tratada con cirugía. La paciente evolucionó favorablemente, retornó a sus actividades y el dolor desapareció. La indicación del tratamiento no solo debe limitarse al grado de inestabilidad de la fractura, sino que también se debe considerar el contexto médico y social del enfermo. Nivel de Evidencia: IV

Pubic stress fracture (PSF) is a rare condition, described in long-distance runners and military recruits. One hundred and ninety-three conservatively managed cases have been documented in the literature. The purpose of this paper is to report an alternatively resolved case, and to review previously reported cases, associated pathologies, diagnosis, and treatment. We report a case of an elderly patient, sportingly active, with PSF, who did not respond to conservative treatment and was surgically treated. Follow-up of the patient was favorable with remission of pain and return to activities. The indication for treatment should not be limited only to the degree of instability of the fracture, but should also take into account the medical and social context of the patient. Level of Evidence: IV

Artrosis rápidamente progresiva de cadera secundaria a una fractura por insuficiencia subcondral del acetábulo. Reporte de un caso / Rapidly progressive osteoarthritis of the hip secondary to a subchondral insufficiency fracture of the acetabulum: A case report

Las fracturas por insuficiencia subcondral son una causa poco frecuente de cadera dolorosa. A diferencia de las fracturas traumáticas agudas, las fracturas por insuficiencia del acetábulo son menos frecuentes que las femorales. Ocurren habitualmente en mujeres posmenopáusicas con comorbilidades. Su diagnóstico inicial suele ser dificultoso y la sospecha clínica es de gran importancia. La resonancia magnética es una herramienta fundamental para detectar este cuadro. Subestimar estas lesiones puede llevar al desarrollo de una artrosis rápidamente progresiva y al reemplazo articular como desenlace. Se presenta el caso de una paciente de 68 años con una fractura por insuficiencia subcondral del acetábulo a quien se le indicó una artroplastia total de cadera no cementada. Nivel de Evidencia: IV

Subchondral insufficiency fractures are a rare cause of hip pain. Unlike acute traumatic fractures, acetabulum insufficiency fractures are less common than femoral fractures. They commonly occur in postmenopausal women with comorbidities. Its initial diagnosis is usually difficult and clinical suspicion is of great importance. Magnetic resonance imaging (MRI) is a fundamental tool for the detection of this pathology. Underestimating these injuries can lead to the development of rapidly progressive osteoarthritis and joint replacement as an outcome. We present the case of a 68-year-old patient with a subchondral insufficiency fracture of the acetabulum who underwent uncemented total hip arthroplasty. Level of Evidence: IV

The Role of Magnetic Resonance in the Diagnosis of Chronic Exertional Compartment Syndrome / O papel da ressonância magnética no diagnóstico da síndrome compartimental crônica do exercício

Abstract Chronic compartment syndrome is a common and often underdiagnosed exercise-induced condition, accounting on average for a quarter of cases of chronic exertional pain in the leg, second only to the fracture/tibial stress syndrome spectrum. It traditionally occurs in young runner athletes, although more recent studies have demonstrated a considerable prevalence in low-performance practitioners of physical activity, even in middle-aged or elderly patients. The list of differential diagnoses is extensive, and sometimes it is difficult to distinguish them only by the clinical data, and subsidiary examinations are required. The diagnosis is classically made by the clinical picture, by exclusion of the differential diagnoses, and through the measurement of the intracompartmental pressure. Although needle manometry is considered the gold standard in the diagnosis, its use is not universally accepted, since there are some important limitations, apart from the restricted availability of the needle equipment in Brazil. New protocols of manometry have recently been proposed to overcome the deficiency of the traditional ones, and some of them recommend the systematic use of magnetic resonance imaging (MRI) in the exclusion of differential diagnoses. The use of post-effort liquid-sensitive MRI sequences is a good noninvasive option instead of needle manometry in the diagnosis of chronic compartment syndrome, since the increase in post-exercise signal intensity is statistically significant when compared with manometry pressure values in asymptomatic patients and in those with the syndrome; hence, the test can be used in the diagnostic criteria. The definitive treatment is fasciotomy, although there are less effective alternatives.

Resumo A síndrome compartimental crônica é uma condição comum e frequentemente subdiagnosticada, induzida pelo exercício, que corresponde em média a um quarto dos casos de dor crônica na perna relacionada ao exercício, e que perde em frequência apenas para o espectro fratura/reação ao estresse tibial. Tradicionalmente ocorre em jovens atletas corredores, embora estudos mais recentes tenham demonstrado uma prevalência considerável em praticantes de atividade física de baixo rendimento, mesmo em pacientes de meia-idade ou idosos. A lista de diagnósticos diferenciais é extensa, e por vezes é difícil fazer a distinção apenas pelos dados clínicos, sendo necessários exames subsidiários. Classicamente, o diagnóstico é feito pelo quadro clínico, pela exclusão dos diferenciais, e pela medida pressórica intracompartimental. Embora a manometria por agulha seja considerada o padrão-ouro no diagnóstico, seu uso não é universalmente aceito, visto que existem algumas limitações importantes, além da disponibilidade restrita do equipamento com agulha no Brasil. Recentemente, novos protocolos de manometria têm sido propostos a fim suplantar a deficiência dos tradicionais, com algum deles inclusive recomendando o uso sistemático da ressonância magnética (RM) na exclusão dos diagnósticos diferenciais. O uso de sequências de RM sensíveis a líquido pós-esforço é uma ótima opção não invasiva à manometria por agulha no diagnóstico da síndrome compartimental crônica, uma vez que o aumento da intensidade de sinal pós-exercício é estatisticamente relevante quando comparados os valores pressóricos de manometria em pacientes com a síndrome e assintomáticos; portanto, o exame pode ser usado no critério diagnóstico. O tratamento definitivo é a fasciotomia, embora existam alternativas menos eficazes.

Tratamiento artroscópico en lesión osteocondral subtalar / Arthroscopic treatment of subtalar osteochondral lesion

Las lesiones osteocondrales de la articulación subtalar es una patología infrecuente y de incidencia variable, dado su reporte principalmente como hallazgo en el estudio de dolor crónico de tobillo y ya con cambios degenerativos articulares. La sospecha clínica y el estudio imagenológico dirigido, permiten investigar esas lesiones en estadios iniciales, evitando así el uso de técnicas que no preservan la articulación para su manejo. La artroscopía subtalar es una excelente herramienta tanto diagnóstica como terapéutica para la resolución de dichas lesiones. Dadas las características anatómicas y biomecánicas de la articulación, en estadios iniciales, el manejo mediante sinovectomía y microfracturas es una alternativa con excelentes resultados funcionales. Este trabajo incluye dos casos de lesiones osteocondrales de la faceta posterior de la articulación subtalar manejadas vía artroscópica mediante sinovectomía y microfracturas y su posterior evolución.

Osteochondral lesions in the subtalar joint are an uncommon pathology with a variable incidence, being mainly reported as a finding in chronic ankle pain studies and with already visible degenerative joint changes at time of diagnosis. Clinical suspicion and directed imaging study, allows to investigate these lesions during early stages, thus avoiding the use of invasive techniques with scarce joint preservation. Subtalar arthroscopy is an excellent diagnostic and therapeutic tool for the resolution of these lesions. Given the anatomical and biomechanical characteristics of the joint, in the early stages the management by synovectomy and microfractures is an alternative with excellent functional results. This study includes two cases of osteochondral lesions of the posterior facet of the subtalar joint managed through arthroscopically synovectomy and microfractures and their subsequent evolution.

Avaliação ex vivo da durabilidade de sistemas de instrumentação de NiTi tratados termicamente / Ex-vivo evaluation of the durability of thermally treated NiTi endodontic files

Objetivo: O presente estudo teve como objetivo comparar três sistemas de instrumentação de NiTi, tratados termicamente, quanto ao número de condutos instrumentados até a fratura. Métodos: Foram utilizados 210 molares humanos inferiores e superiores com curvaturas leves a moderadas, comprimentos reais entre 19 e 21 mm e forames apicais até 200µm. Esses foram randomicamente divididos em três grupos de acordo com o sistema de instrumentação utilizado: Reciproc (REC; R25), ProDesign Duo Híbrido (PDH; #25/.01 e #25/.08) e TF Adaptive (TFA; #25/.08). Foram utilizados 5 instrumentos/kits de cada sistema. Registrou-se, então, o número de condutos instrumenta- dos até a fratura e o número de reinserções necessárias até o alcance do comprimento de trabalho. Resultados: A análise estatística apontou diferenças significativas quando comparada a durabilidade dos sistemas, tendo os instrumentos do grupo PDH oferecido os maiores valores (29,2), seguido de REC (21,6) e TFA (15,4) (p<0,05). Quanto ao número de reinserções, o sistema TFA foi o que necessitou do menor número de reinserções (p<0,05). Conclusão: Nas condições do estudo, pode-se concluir que o sistema ProDesign Duo Híbrido foi o mais durável; ainda que o sistema TF Adaptive tenha alcançado o comprimento de trabalho com maior facilidade

Objective: The present study compared three systems of thermally treated NiTi endodontic files regarding their achieved number of prepared root canals before fracture. Methods: Two hundred and ten slightly and moderately curved upper and lower molars with actual length ranging from 19 to 21 mm and apex foramens diameters up to 200 µm were used. The sample was allotted to three groups according to the instrumentation system in use: Reciproc (REC; R25), ProDesign Duo Hybrid (PDH; #25/.01 and #25/.08), and TF Adaptive (TFA; #25/.08). Five instruments/kits of each system were used. Then, it was registered the number of root canals prepared until the instrument fractured and the number of reinsertions needed until the working length was achieved. Results: The statistical analysis showed significant differences among the durability of the three systems, being the instruments of group PDH the ones that yielded higher reuses (29.2) followed by groups REC (21.6), and TFA (15.4) (P < .05). Regarding the number of insertions, the TFA system was the one that needed the lowest number of reinsertions (P < .05). Conclusion: Under this study conditions, ProDesign Duo Hybrid was the most durable system, whereas TF Adaptive system was the one that most easily achieved the working length.

Fractura de húmero por estrés en lanzador de beisbol. Presentación de un caso / Humerus fracture by stress in baseball pitcher. Case presentation

RESUMEN Se presentó el caso de un adolescente que sufrió fractura por estrés del húmero izquierdo, mientras lanzaba en un partido de béisbol. Las fracturas de húmero por estrés son infrecuentes. Generalmente ocurre en los atletas que practican deportes de lanzamiento, es más frecuente en los lanzadores de béisbol amateurs de poca experiencia. Esta lesión es debida a la tracción muscular incoordinada y fuerza de torsión cuando la pelota es lanzada, asociada a la fatiga física. Puede ocurrir a nivel de los tercios medio y superior del húmero, entre las inserciones del deltoides y el pectoral mayor, así como en el tercio distal. Es común la presencia de dolor poco antes de producirse la fractura. Se enfatizó en la importancia de tener presente la posibilidad de presentación de este tipo de fractura en los atletas que practican deportes de lanzamientos, así como tener presente además las complicaciones que puedan presentarse a partir de este tipo de lesión. Se analizaron los datos recogidos en la historia clínica del paciente. Es importante pensar en este tipo de lesión, pues en ocasiones el cuadro clínico no es evidente. Se señaló además la necesidad de realizar un estricto seguimiento del paciente ante la posibilidad de lesión del nervio radial (AU).

ABSTRACT The authors present the case of a teenager who suffered left humerus fracture due to stress while he was pitching a baseball game. Humerus fractures caused by stress are infrequent. They commonly occur in athletes practicing throwing sports, being more frequent in amateur baseball pitchers with little experience. This lesion is due to uncoordinated muscular traction and torsion strength when the ball is thrown, all associated to physical fatigue. It can happen at the level of the medial and upper third of the humerus, between the insertions of deltoids and pectoral major muscles, and also in the distal third. The presence of pain is common a little before the fracture happens. The authors emphasize in the importance of taking into account the possibility of this kind of fracture occurring in athletes practicing throwing sports, and also the complications appearing after this kind of lesion. Data collected from the patient?s clinical record were analyzed. It is important to think in this kind of lesion because sometimes clinical characteristics are not evident. It was also pointed out the necessity of performing a strict follow-up of the patient given the possibility of radial nerve lesion (AU).

Factores asociados a fractura por estrés: estudio de casos y controles en un centro médico de la marina de guerra de Perú / Factors associated with stress fracture: a case-control study in a Peruvian navy medical center

INTRODUCCIÓN: Las fracturas por estrés son lesiones producidas por el sobreuso de ciertas extremidades, generando fatigas repetitivas en el hueso con insuficientes periodos de descanso, trastornos hormonales, entre otras. Se produce una elevada actividad osteoclástica y una menor actividad de los osteoblastos a nivel cortical. OBJETIVO: Determinar los factores asociados a fractura por estrés en un centro médico de la Marina de Guerra de Perú. METODOLOGÍA: Se realizó una investigación de tipo observacional analítica de casos y controles. La variable dependiente fue la fractura por estrés, confirmada por resonancia magnética de los pacientes. Las variables independientes fueron edad, sexo y nivel de calcemia tomadas a partir de la historia clínica; el nivel socioeconómico y tiempo de actividad física diaria fueron datos recogidos mediante encuesta. Se obtuvieron los Odds ratio crudos y ajustados con un intervalo de confianza de 95%. RESULTADOS: Se trabajó con un total de 238 pacientes (119 casos y 119 controles), de los cuales 79,8% fueron varones y 20,2% fueron mujeres; la media de edad fue de 20,25 años. En el análisis bivariado se encontró asociación de fracturas por estrés con el sexo masculino (Odds ratio: 3,00; intervalo de confianza 95%: 1,51 a 5,95), hipocalcemia (Odds ratio: 2,83; intervalo de confianza 95%: 2,32 a 3,44), más de dos horas de actividad física diaria (Odds ratio: 24,74; intervalo de confianza 95%: 12,51 a 48,95) y un nivel socioeconómico C (Odds ratio: 6,66; intervalo de confianza 95%: 2,82 a 15,74). Mantuvieron su asociación en el análisis multivariado el tiempo de actividad física (Odds ratio: 44,46; intervalo de confianza 95%: 17,93 a 110,22) y el nivel socioeconómico C (Odds ratio: 22,57; intervalo de confianza 95%: 7,03 a 72,74). CONCLUSIÓN: Las fracturas por estrés estuvieron asociadas al tiempo de actividad física y a un nivel socioeconómico menor. Son necesarios más estudios para evaluar la relación con otros factores en la población militar de Perú.

INTRODUCTION: Stress fractures are injuries produced by the overuse of certain extremities, generating repetitive fatigue in the bone with insufficient rest periods and hormonal disorders, among others. High osteoclastic activity and lower activity of the osteoblasts at the cortical level occurs. OBJECTIVE: To determine the factors associated with a stress fracture in a single medical center of the Peruvian navy. METHODS: We conducted an observational, analytical case-control study. The dependent variable was stress fracture confirmed by magnetic resonance imaging of the patients; the independent variables were age, sex, calcemia, socioeconomic status, and time of daily physical activity. All data were extracted from the medical records. Crude and adjusted odds ratios were calculated with 95% confidence intervals. RESULTS: The sample was comprised of 238 patients (119 cases and 119 controls), of which 79.8% were male, and 20.2% were female; the average age was 20.25. In the bivariate analysis, stress fractures were associated with male sex (odds ratio 3.00; 95% confidence interval 1.51 to 5.95), hypocalcemia (2.83; 2.32 to 3.44), more than two hours of daily physical activity (24.7; 12.51 to 48.95) and socioeconomic level C (6.66; 2.82 to 15.74). Time dedicated to physical activity (adjusted odds ratio 44.46; 95% confidence interval 17.93 to 110.22) and socioeconomic level C (adjusted odds ratio 22.57; 95% confidence interval 7.03 to 72.74) were associated in the multivariate analysis. CONCLUSION: We found that stress fractures were associated with physical activity time and a lower socioeconomic level. Further studies are needed to evaluate the relationship with other factors in the military population of Peru.

Simultaneous Bilateral Knee Varus Stress Radiographic Technique / Técnica radiográfica de estresse em varo bilateral simultâneo

Abstract Varus stress radiographs are reported as an effective and cost-beneficial diagnostic and decision-making tool for lateral knee injuries, both in the acute and chronic settings. The opening of the lateral compartment is reported to vary according to the number of structures injured, helping to differentiate isolated fibular collateral ligament injury from grade-III posterolateral corner injury. The conventional technique requires the physician or another healthcare provider to applymanual varus stresswhile obtaining the radiograph on one knee at a time. The present study aimed to describe, in detail, the preferred method of the authors to assess the opening of the lateral compartment in both knees simultaneously, which also avoids the need for the examiner to be present in the imaging room.

Resumo As radiografias de estresse em varo são descritas como uma técnica efetiva e econômica de diagnóstico e tomada de decisão em lesões laterais do joelho, tanto no contexto agudo quanto crônico. A abertura do compartimento lateral varia de acordo com o número de estruturas danificadas, ajudando a diferenciar lesões isoladas do ligamento colateral fibular das lesões do canto posterolateral de grau III. A técnica convencional exige que o médico ou outro profissional de saúde aplique estresse em varo manual ao obter a radiografia em um joelho de cada vez. O presente estudo teve como objetivo descrever, em detalhes, o método preferido dos autores para avaliar a abertura do compartimento lateral em ambos os joelhos simultaneamente, o que também evita a necessidade da presença do examinador na sala de imagem.

Fractura de estrés de cadera en adulto no entrenado tras actividad deportiva intensa. Reporte de caso / Adult untrainned Hip stress fracture. Case Report

En la actualidad es cada vez mayor el número de adultos jóvenes que inician actividad deportiva sin valoración previa de su acondicionamiento físico. En los atletas maduros, con mayor riesgo de presentar hueso osteoporótico, pueden aparecer fracturas por estrés ante traumatismos de menor intensidad repetitivos. En el dolor de cadera en el adulto es importante tener presente la fractura por estrés de cuello femoral, realizando las maniobras exploratorias que permitan su diagnóstico y pedir la prueba de imagen más indicada. Ante una alta sospecha y estudio radiográfico normal debe considerarse la realización de TAC o RMN. El diagnóstico precoz y tratamiento oportuno de esta patología disminuye el riesgo de complicaciones y ofrece la posibilidad de optimizar el uso de recursos.

The number of young adults who start sports activity without prior assessment of their physical conditioning is increasing. In mature athletes, with a higher risk of presenting osteoporotic bone, stress fractures may occur due to repetitive minor trauma. When assesing hip pain in adults it is important to keep in mind femoral neck stress fracture, as well as how to perform exploratory maneuvers that allow diagnosis and request the most appropriate imaging test. In case of high suspicion and normal radiographic study, CT or MRI should be considered. Early diagnosis and timely treatment of this pathology reduces the risk of complications and offers the possibility of optimizing the use of resources.

Implantación de condrocitos autólogos versus microfracturas para el tratamiento de lesiones del cartílago en la rodilla / Autologous chondrocytes implantation versus microfracture for the treatment of knee cartilage lesions

Resumen: Objetivo: Comparar la eficacia clínica y la seguridad de la terapia de microfracturas (MF) versus implantación de condrocitos autólogos en membrana (MACI) en el manejo de lesiones condrales de rodilla ≥ 3 cm2 y el seguimiento a 12 meses postratamiento. Material y métodos: Se realizó un estudio de cohorte retrospectiva, de Enero de 2016 a Diciembre de 2017. Se incluyeron pacientes con una o varias lesiones condrales en rodilla ≥ 3 cm2 para comparar la terapia MF versus MACI para la reparación de lesión condral. Se realizaron valoraciones clínicas y funcionales previas al tratamiento quirúrgico y 12 meses posteriores, con medición de los arcos de movimiento, escala EVA, Oxford e índice de Lequesne. Resultados: Se incluyeron 12 pacientes en MF y 12 pacientes en MACI. La lesión más frecuente se localizó en la patela en ocho pacientes (67%). Se demostró incremento en los arcos de movimiento, así como mejoría en la comparación entre el nivel basal y en el seguimiento a 12 meses: en EVA, MF mostró 48.4% y MACI 57.5% (p ≤ 0.05); escala de Oxford: MF 32.65% y MACI 51.04% (p ≤ 0.05); índice de Lequesne: MF 40.12% y MACI 50%. Se presentaron dos casos de derrame articular en MACI, que se resolvieron con la realización de artrotomías. Conclusión: En este estudio se demostró mejoría significativa en MACI con alivio del dolor, funcionalidad y arcos de movimiento en comparación con el tratamiento de MF en lesiones ≥ 3 cm2 del cartílago articular de rodilla después de un año de seguimiento.

Abstract: Objective: To compare the clinical efficacy and safety of microfracture therapy (MF) versus implantation of autologous chondrocytes (MACI) in the management of chondral lesions of the knee ≥ 3 cm2 and follow up to 12 months post treatment. Material and methods: A retrospective cohort study was conducted from January 2016 to December 2017. Patients with one or more chondral lesions in knee ≥ 3 cm2 were included to compare MF versus MACI therapy for the repair of chondral lesion. Clinical and functional evaluations were carried out prior to the surgical treatment and 12 months later, with measurement of the range of motion, EVA, Oxford scale and Lequesne index. Results: Twelve patients were included in MF and 12 patients in MACI. The most frequent lesion was located in the Patella in eight patients (67%). It showed an increase in the arcs of motion, as well as improvement in the comparison between baseline and follow-up at 12 months: in EVA, MF demonstrated 48.4% and MACI 57.5% (p ≤ 0.05); Oxford scale: MF 32.65% and MACI 51.04% (p ≤ 0.05); index of Lequesne: MF 40.12% and MACI 50%. Two cases of joint effusion were presented in MACI, which were resolved with the realization of arthrotomies. Conclusion: In this study, significant improvement was demonstrated in MACI with pain relief, functionality, and range of motion compared to the treatment of MF in lesions ≥ 3 cm2 of the articular cartilage of the knee after one year of follow-up.

Enclavado femoral y artroplastía total de rodilla en un tiempo en una paciente con fractura diafisaria femoral por estrés / Interlocking femoral nail and total knee Arthroplasty in one stage for a patient with a femoral diaphyseal stress fracture

Resumen: Presentamos el caso de una mujer de 81 años de edad, en seguimiento por el Servicio de Reumatología por osteoporosis y tratada con bifosfonatos durante más de cinco años. Refirió una fractura del tercio distal del fémur contralateral por mecanismo de baja energía, tratada con enclavado intramedular retrógrado el año anterior. Presentó una clínica de cruralgia y gonalgia izquierda, sin traumatismo previo. Se le realizó una gammagrafía y radiografías que apoyaron el diagnóstico de fractura de estrés del tercio distal del fémur izquierdo y osteonecrosis del cóndilo femoral interno izquierdo. Pensando en las posibles complicaciones de llevar a cabo dos intervenciones en una paciente de avanzada edad, se decidió efectuar el tratamiento en un tiempo y por el mismo abordaje quirúrgico, tratando de resolver la osteonecrosis y la fractura a la vez, con el objetivo de una rehabilitación precoz y menor morbilidad. Se realizó un enclavado profiláctico retrógrado femoral para estabilizar la fractura de estrés y se implantó una prótesis de rodilla primaria retentiva para el ligamento cruzado posterior por el mismo abordaje quirúrgico. No hubo incidencias en el postoperatorio inmediato; se inició deambulación con ayuda a las 48 horas de la intervención. La fractura consolidó y la paciente presentó un buen resultado funcional de la rodilla, tanto en el postoperatorio inmediato como a los tres años de seguimiento.

Abstract: We present the case of an 81-year-old woman who was followed up by the Rheumatology Service for osteoporosis and treated with bisphosphonates for more than five years. She reported a fracture of the distal third of the contralateral femur by a low energy mechanism, treated with retrograde intramedullary nailing the previous year. She presented a clinic of cruralgia and left gonalgia, without previous trauma. A scintigraphy and radiographs were performed to support the diagnosis of stress fracture of the distal third of the left femur and osteonecrosis of the left internal femoral condyle. Thinking about the possible complications of performing two interventions in an elderly patient, we decided to complete the treatment in a single time and by the same surgical approach, trying to resolve the osteonecrosis and the fracture at the same time, with the objective of an early rehabilitation and lower morbidity. A femoral retrograde prophylactic nailing was performed to stabilize the stress fracture and a retentive primary knee prosthesis was implanted for the posterior cruciate ligament by the same surgical approach. There were no incidents in the immediate postoperative period, with ambulation beginning with help 48 hours after the intervention. The fracture consolidated and the patient presented a good functional result of the knee, both in the immediate postoperative period and at three years of follow-up.

Fractura por estrés del cuello del fémur en una niña hiperactiva tratada con metilfenidato: Reporte de caso / Femoral neck stress fracture in a hyperactive child taking methylphenidate. Case report

Las fracturas por estrés afectan, con mayor frecuencia, a personas físicamente activas con hueso normal y son infrecuentes en los niños con placa de crecimiento abierta. Aun más infrecuentes son las fracturas por estrés del cuello femoral en la población pediátrica. Sin embargo, constituyen entidades muy importantes debido al riesgo de complicaciones graves, como la necrosis avascular. Se describe el caso de una niña de 7 años medicada con metilfenidato que sufrió una fractura por estrés del cuello del fémur atípica. La paciente consulta por dolor inguinal derecho sin limitaciones en las actividades cotidianas. La radiografía muestra una fractura por estrés del cuello del fémur, que se confirma con tomografía. Se instaura un tratamiento conservador, y la paciente está asintomática a las cuatro semanas. Este caso representa una alerta sobre esta infrecuente entidad en la que podrían presentarse errores diagnósticos. Investigaciones recientes también sugieren la posible participación de fármacos, como el metilfenidato, en la desmineralización ósea, que podría constituir un posible factor de riesgo de fractura. Nivel de Evidencia: IV

Stress fractures most commonly affect physically active individuals with normal bone, and they are rare in children with open growth plates. Even rarer are femoral neck stress fractures in pediatric age. Nevertheless, they constitute a very important entity due to the risk of severe complications, such as avascular necrosis. A seven-year-old girl, treated with methylphenidate, who suffered an atypical femoral neck stress fracture is presented. Patient complained of right inguinal pain without daily life activity limitations. The radiograph showed a stress femoral neck fracture, confirmed by CT imaging. Conservative treatment was instituted and the patient became asymptomatic after 4 weeks. This case report alerts the clinicians about this rare entity that might be misdiagnosed. Recent research also suggests a possible involvement of drugs, such as methylphenidate, in bone demineralization, which might constitute a possible risk factor for fractures. Level of Evidence: IV

Evaluación de score de hueso trabecular (TBS) en pacientes menopáusicas con fracturas y sin ellas / Trabecular bone score evaluation in postmenopausal women with or without fractures

El score de hueso trabecular (TBS, Trabecular Bone Score) es una medición de la textura de los grises derivada de la evaluación del raquis por DXA y proporciona un índice de la microarquitectura ósea. Se ha demostrado que los valores bajos presentan capacidad para predecir fracturas. Nuestro objetivo fue evaluar si existían diferencias entre los valores de TBS de pacientes con fracturas frente a no fracturadas. Materiales y métodos: se revisaron 159 historias clínicas de mujeres menopáusicas que consultaron para evaluación de su salud ósea. Se consideraron los antecedentes autorreferidos de fracturas (Fx), la DMO de raquis, cuello femoral y fémur total y TBS. Resultados: treinta pacientes (18,9%) presentaron fracturas y en ellas se observó menor TBS (con Fx: 1,295±83 vs. sin Fx: 1,366±84, p<0,0001), menor índice de masa corporal (IMC) (con Fx: 23,7±1,9 vs. sin Fx: 25,7±4,2, p=0,02), sin diferencias en la edad (p=0,39), ni en valores de DMO (L1-L4 p=0,11, cuello femoral p=0,20 y fémur total p= 0,12). Muchas de las fracturas ocurrieron en pacientes sin osteoporosis por DXA. Conclusiones: el TBS aumentaría la capacidad de DXA para identificar a mujeres argentinas en riesgo de padecer fracturas sin tener osteoporosis densitométrica. Este es el primer trabajo realizado en la Argentina con medición de TBS. (AU)

Trabecular Bone Score (TBS) is a measure of the grey scale derived from DXA lumbar image and provides information about microarchitecture. It has been shown that low TBS values can predict fractures. Our objective was to evaluate if there are any differences between the TBS values in patients with fractures vs. non-fractures. Materials and methods: We reviewed 159 medical records of menopausal women who consulted for evaluation of their bone health. Self-reported fractures (Fx), spine BMD, femoral neck and total femur and TBS were evaluated. Results: thirty patients (18.9%) presented fractures and they showed lower TBS (with Fx: 1,295±0,083 vs. without Fx: 1,366±0,084, p<0.0001), lower body mass index (BMI) (with Fx: 23.7±1.9 vs. without Fx 25.7±4.2, p=0.02), without differences in ages (p=0.39) or in BMD values (L1-L4 p=0.11, femoral neck p=0.20 and total femur p=0.12). Some fractures occurred in patients without osteoporosis, as determined by DXA. Conclusions: TBS would increase the ability of DXA to identify Argentine women at risk for fractures without densitometric osteoporosis. This is the first work done in Argentina with TBS measurement. (AU)