Influence of the size of the cities of birth and residence in the sports career: an analysis through the bolsa-atleta program / Influência do tamanho das cidades de nascimento e residência na carreira desportiva: uma análise por meio do programa bolsa-atleta

ABSTRACT This study aimed to verify whether the size of municipalities in which Brazilian high-performance athletes are born or live influences the federal government subsidy, in addition to pointing out whether factors such as human development index, demographic density and municipal investment in sports also exert influence. The sample consisted of 2,033 Brazilian municipalities that had athletes, born or resident, receiving the Brazilian incentive Bolsa-Atleta program. The size of municipalities influences the amount and level of grant obtained, demonstrating that the smaller the population size, the lower the chance of obtaining a higher grant level. In addition, factors such as human development index, demographic density and investment in sport influence the acquisition of grants by athletes, mainly by resident athletes, which shows an internal sports migration in the country as a result.

RESUMO O presente estudo teve por objetivo verificar se o tamanho dos municípios em que os atletas brasileiros de rendimento nascem ou residem gera influência na obtenção de subsídio pelo governo federal, além de apontar se fatores como índices de desenvolvimento humano, densidade demográfica e investimento municipal no esporte também exercem influência. A amostra consistiu em 2033 municípios brasileiros que apresentaram atletas nascidos ou residentes contemplados pelo programa de incentivo brasileiro Bolsa-Atleta. Por meio da análise, pode-se verificar que o tamanho dos municípios influência na quantidade e no nível de bolsa obtido, demonstrando que quanto menor o tamanho da população, menor a chance de se obter um nível mais alto de bolsa. Além disto, pode-se notar que fatores como índices de desenvolvimento humano, densidade demográfica e investimento no esporte exercem influência na aquisição de bolsas pelos atletas, principalmente, por parte de atletas residentes, o que evidencia uma migração esportiva interna no país.

Identificación de las zonas con dificultades geográficas de acceso a los servicios públicos de salud en Costa Rica: una propuesta metodológica / Identification of areas with geographical access difficulties to public health services in Costa Rica: a methodological proposal

Objetivo: el propósito de este estudio es presentar y aplicar una herramienta metodológica para identificar las zonas en las cuales el acceso a los servicios de salud pudiera resultar difícil para la población debido a la barrera geográfica, tanto por su distancia al centro médico, como por su capacidad de desplazamiento, específicamente en los cantones de Curridabat, Escazú y Desamparados. Métodos: a partir de la división geográfica del país en unidades geoestadísticas mínimas realizada por el Instituto Nacional de Estadísticas y Censos, se calculó, por cada unidad, la distancia en minutos que se tardaría en recorrer caminando, por la ruta real más rápida, desde la unidad geoestadística mínima hasta la sede de su equipo básico de atención en salud asignado. Resultados: el 3,4% de la población estudiada vivía en una unidad geoestadística mínima clasificada como con dificultad importante de acceso a los servicios de salud, pues presentaba tanto la barrera física de la distancia, como poco desplazamiento en automotores y baja condición socioeconómica. Se identificaron 65 unidades geoestadísticas mínimas (sobre 2014 incluidas en el estudio) que se encontraban a más de 20 minutos caminando de la sede de su equipo básico de atención en salud y cuya población contaba con baja capacidad de desplazamiento y baja condición socioeconómica; la mayoría de ellas en el Área de Salud de Desamparados. Conclusión: este estudio presenta una herramienta metodológica para aplicar en la identificación de zonas a cuya población le pudiera resultar difícil el acceso geográfico a los servicios de salud, tanto por su distancia a un centro médico, como por su capacidad de desplazamiento, específicamente en los cantones de Curridabat, Escazú y Desamparados.

Aim: The objective of this study is to present and apply a methodological tool to identify the areas in which the inhabitants could have geographic access difficulties as a barrier to access to health services, both because of its distance from the health center and its mobility capacity, specifically in the cantons of Curridabat, Escazú and Desamparados. Methods: Based on the geographical division of the country into minimum geostatistical units carried out by the Instituto Nacional de Estadísticas y Censos, the distance in minutes that it would take to walk it was calculated for each unit, based on the actual fastest route between the minimum geostatistical unit and the headquarters of its assigned basic health care team. Results: An 3.4% of the studied population lived in a minimum geostatistical unit classified as having significant difficulty accessing health services since they accumulated both the physical barrier of distance and little mobility in automobiles. 65 minimum geostatistical units were identified (out of 2014 included in the study) as being at more than 20 minutes walking from the basic health care team, with a population with low mobility capacity, and consequently low socioeconomic status. Most of these were found in the Desamparados Health Area. Conclusion: This study presents and applies a methodological tool to identify the areas in which the inhabitants could have geographic access difficulties as a barrier to access to health services, both due to their distance from the health center and their mobility capacity, in Curridabat, Escazú and Desamparados.

Mortality inequalities measured by socioeconomic indicators in Brazil: a scoping review

ABSTRACT OBJECTIVE Summarize the literature on the relationship between composite socioeconomic indicators and mortality in different geographical areas of Brazil. METHODS This scoping review included articles published between January 1, 2000, and August 31, 2020, retrieved by means of a bibliographic search carried out in the Medline, Scopus, Web of Science, and Lilacs databases. Studies reporting on the association between composite socioeconomic indicators and all-cause, or specific cause of death in any age group in different geographical areas were selected. The review summarized the measures constructed, their associations with the outcomes, and potential study limitations. RESULTS Of the 77 full texts that met the inclusion criteria, the study reviewed 24. The area level of composite socioeconomic indicators analyzed comprised municipalities (n = 6), districts (n = 5), census tracts (n = 4), state (n = 2), country (n = 2), and other areas (n = 5). Six studies used composite socioeconomic indicators such as the Human Development Index, Gross Domestic Product, and the Gini Index; the remaining 18 papers created their own socioeconomic measures based on sociodemographic and health indicators. Socioeconomic status was inversely associated with higher rates of all-cause mortality, external cause mortality, suicide, homicide, fetal and infant mortality, respiratory and circulatory diseases, stroke, infectious and parasitic diseases, malnutrition, gastroenteritis, and oropharyngeal cancer. Higher mortality rates due to colorectal cancer, leukemia, a general group of neoplasms, traffic accident, and suicide, in turn, were observed in less deprived areas and/or those with more significant socioeconomic development. Underreporting of death and differences in mortality coverage in Brazilian areas were cited as the main limitation. CONCLUSIONS Studies analyzed mortality inequalities in different geographical areas by means of composite socioeconomic indicators, showing that the association directions vary according to the mortality outcome. But studies on all-cause mortality and at the census tract level remain scarce. The results may guide the development of new composite socioeconomic indicators for use in mortality inequality analysis.

Proteomics, toxicity and antivenom neutralization of Sri Lankan and Indian Russell's viper (Daboia russelii) venoms

The western Russell's viper (Daboia russelii) is widely distributed in South Asia, and geographical venom variation is anticipated among distant populations. Antivenoms used for Russell's viper envenomation are, however, raised typically against snakes from Southern India. The present study investigated and compared the venom proteomes of D. russelii from Sri Lanka (DrSL) and India (DrI), the immunorecognition of Indian VINS Polyvalent Antivenom (VPAV) and its efficacy in neutralizing the venom toxicity. Methods: The venoms of DrSL and DrI were decomplexed with C18 high-performance liquid chromatography and SDS-polyacrylamide gel electrophoresis under reducing conditions. The proteins fractionated were identified through nano-ESI-liquid chromatography-tandem mass spectrometry (LCMS/MS). The immunological studies were conducted with enzyme-linked immunosorbent assay. The neutralization of the venom procoagulant effect was evaluated in citrated human plasma. The neutralization of the venom lethality was assessed in vivo in mice adopting the WHO protocol. Results: DrSL and DrI venom proteomes showed comparable major protein families, with phospholipases A2 (PLA2) being the most abundant (> 60% of total venom proteins) and diverse (six protein forms identified). Both venoms were highly procoagulant and lethal (intravenous median lethal dose in mice, LD50 = 0.24 and 0.32 µg/g, for DrSL and DrI, respectively), while lacking hemorrhagic and anticoagulant activities. VPAV was immunoreactive toward DrSL and DrI venoms, indicating conserved protein antigenicity in the venoms. The high molecular weight venom proteins were, however, more effectively immunorecognized than small ones. VPAV was able to neutralize the coagulopathic and lethal effects of the venoms moderately. Conclusion: Considering that a large amount of venom can be injected by Russell's viper during envenomation, the potency of antivenom can be further improved for optimal neutralization and effective treatment. Region-specific venoms and key toxins may be incorporated into the immunization procedure during antivenom production.(AU)

Geographic variation of individual venom profile of Crotalus durissus snakes

South American rattlesnakes are represented in Brazil by a single species, Crotalus durissus, which has public health importance due to the severity of its envenomation and to its wide geographical distribution. The species is subdivided into several subspecies, but the current classification is controversial. In Brazil, the venoms of C. d. terrificus and C. d. collilineatus are used for hyperimmunization of horses for antivenom production, even though the distinction of these two subspecies are mostly by their geographical distribution. In this context, we described a comparative compositional and functional characterization of individual C. d. collilineatus and C. d. terrificus venoms from three Brazilian states. Methods: We compared the compositional patterns of C. d. terrificus and C. d. collilineatus individual venoms by 1-DE and RP-HPLC. For functional analyzes, the enzymatic activities of PLA2, LAAO, and coagulant activity were evaluated. Finally, the immunorecognition of venom toxins by the crotalic antivenom produced at Butantan Institute was evaluated using Western blotting. Results: The protein profile of individual venoms from C. d. collilineatus and C. d. terrificus showed a comparable overall composition, despite some intraspecific variation, especially regarding crotamine and LAAO. Interestingly, HPLC analysis showed a geographic pattern concerning PLA2. In addition, a remarkable intraspecific variation was also observed in PLA2, LAAO and coagulant activities. The immunorecognition pattern of individual venoms from C. d. collilineatus and C. d. terrificus by crotalic antivenom produced at Butantan Institute was similar. Conclusions: The results highlighted the individual variability among the venoms of C. durissus ssp. specimens. Importantly, our data point to a geographical variation of C. durissus ssp. venom profile, regardless of the subspecies, as evidenced by PLA2 isoforms complexity, which may explain the increase in venom neurotoxicity from Northeastern through Southern Brazil reported for the species.(AU)

Orthomene (Menispermaceae) in the Brazilian Amazon / Orthomene (Menispermaceae) na Amazônia brasileira

Orthomene comprises four species distributed from Central to South America, of which three occur in phytogeographic domains of Brazil. In Brazil, Amazonia is the main center of diversity for the genus. This work is a taxonomic treatment of Orthomene in Brazil and involved analyzing field collections (between January 2017 and July 2018), types and botanical specimens from 32 national and foreign herbaria. The three species in the study area are Orthomene hirsuta,Orthomene prancei and Orthomene schomburgkii. The latter is the most common and widely distributed species of the genus in the country. An identification key, descriptions, illustrations, distribution data, and additional comments for each species are provided. (AU)

Orthomene possui quatro espécies, distribuídas desde a América Central até a América do Sul, sendo que três ocorrem nos domínios fitogeográficos brasileiros. No Brasil, a Amazônia brasileira é considerada o principal centro de diversidade do gênero. O tratamento taxonômico envolveu a análise de material coletado (entre janeiro de 2017 e julho de 2018), tipos e amostras dos espécimes de Orthomene depositados em 32 herbários nacionais e estrangeiros. O gênero está representado na área de estudo por três espécies: Orthomene hirsuta,Orthomene prancei e Orthomene schomburgkii, sendo esta última a mais comum e amplamente distribuída nas regiões brasileiras de sua ocorrência. São apresentadas uma chave de identificação, descrições e ilustrações das espécies, bem como dados adicionais sobre distribuição geográfica e comentários sobre as mesmas.(AU)

Streptococcus agalactiae - Distribuição sorotípica e relação com fatores de virulência e resistência antimicrobiana / Streptococcus agalactiae - Serotype distriburion and correlation with virulence factors and antibiotic resistance

Streptococcus agalactiae, ou Estreptococo do Grupo B, é um microrganismo que encontrado na microbiota intestinal, vaginal e/ou geniturinária de 10-30% de mulheres saudáveis. A principal infecção causada por S. agalactiae é a sepse neonatal. O bebê pode adquirir o microrganismo durante o parto ao passar pelo canal vaginal, ou até mesmo durante a gestação, caso haja ascensão de S. agalactiae para o útero. Existem diversos fatores associados à infecção do feto por S. agalactiae quando a mãe é colonizada, tais como fator CAMP, cápsula de polissacarídeos, hialuronidase, ß-citolisina/hemolisina e pili. Não existe consenso ou recomendação técnica sobre o tema no Brasil. Segundo o Caderno de Atenção Básica ao Pré-Natal, não existem estudos que levem à recomendação da antibioticoterapia intraparto. É necessário elucidar as características genotípicas de cepas de S. agalactiae isoladas no Brasil para alinhar as práticas clínicas às características fenotípicas do microrganismo. Desta forma, os objetivos deste projeto são: i) classificar cepas de S. agalactiae isoladas de gestantes e não gestantes quanto ao sorotipo capsular, por PCR Multiplex, ii) avaliar a presença e distribuição de fatores de virulência, por PCR e iii) avaliar o perfil de resistência antimicrobiana, pelo método de disco difusão e teste D. Os achados de virulência e resistência a antimicrobianos foram comparados com os sorotipos, gestação, localização geográfica e sítio de isolamento. Foram analisadas 292 cepas isoladas de gestantes e não gestantes em São Paulo, São José dos Campos e Rio de Janeiro. O sorotipo Ia foi o mais prevalente entre as cepas. Na cidade de São José dos Campos não houve diferença significativa entre a prevalência dos sorotipos Ia e V, sendo que o sorotipo V foi mais abundante do que nas cidades de São Paulo e Rio de Janeiro. O sorotipo II foi mais abundante em mulheres não gestantes do que gestantes. Não foram encontradas cepas resistentes à Penicilina e vancomicina; contudo a resistência a Cefepima, Eritromicina e Clindamicina ficou em torno de 22%. Foram encontradas diferenças entre os sorotipos quanto à resistência, genes de virulência e sítio de isolamento das cepas. Portanto essas diferenças podem se refletir no perfil epidemiológico da infecção por S. agalactiae quanto à localização geográfica também quanto à gestação. A incidência de sepse causada por S. agalactiae diminuiu muito nas últimas décadas, contudo o monitoramento constante é necessário para alinhar as práticas clínicas às características fenotípicas do microrganismo

Streptococcus agalactiae, or Group B Streptococcus, is a microorganism found in intestinal, vaginal and/or genitourinary microbiota from about 10-30% of all healthy women. The main infection caused by S. agalactiae is neonatal sepsis. The baby can contract the infection during labor when passing through the vaginal canal, or even during pregnancy, if S. agalactiae ascends from the vaginal canal to the uterus. There are several factors associated to the infection of the fetus by S. agalactiae when the mother is colonized, such as the CAMP factor, polysaccharide capsule, hyaluronidase, ß-cytolysin/hemolysin and pili. There is no consensus or technical recommendation regarding this theme in Brazil. According to the Brazilian guidelines to prenatal care, there is no research that justifies the implementation of intrapartum antibiotic therapy. There is a need to clarify genotype characteristics of S. agalactiae strains isolated in Brazil in order to align clinical practices to phenotypical characteristics of this microorganism. This way, the goals of this project are: i) to classify S. agalactiae strains isolated from pregnant and nonpregnant women according to their capsular serotype, using PCR Multiplex, ii) to evaluate the presence and distribution of virulence factors, using PCR and iii) to evaluate their antibiotic resistance profile, using disk-diffusion and D-zone tests. The findings regarding virulence and resistance were compared to serotypes, pregnancy, geographic localization and the site where the sample was isolated. A total of 292 strains from pregnant and nonpregnant women from the cities of São Paulo, São José dos Campos and Rio de Janeiro were analyzed. Serotype Ia was the most prevalent among the strains. In São José dos Campos there was no significate difference in the prevalence of serotypes Ia and V. Serotype V was the most abundant in São Paulo and Rio de Janeiro. Serotype II was most prevalent in nonpregnant women when compared to pregnant women. No resistance to Penicillin nor Vancomycin was found. However, resistance to Cefepime, Erythromycin or Clindamycin was found in around 22% of strains. There were differences among serotypes regarding resistance, virulence genes and site where the strain was isolated. Therefore these differences can reflect into the epidemiologic profile of S. agalactiae infection in regards to geographic localization and pregnancy. The incidence of sepsis caused by S. agalactiae has decrease in the last few decades, however constant monitoring is necessary in order to align clinical practice to the microorganisms phenotypical characteristics

Map showing roads, airstrips, police outposts/stations, mining and forest stations in Guyana

Map of Guyana utilizes a colour key to identify the number of locations where malaria microscopy is done; the main malaria hot spots; and the main health facilities.

Altitud geográfica de residencia y dependencia alcohólica en pobladores peruanos / Geographic Altitude of Residence and Alcohol Dependence in a Peruvian Population

El objetivo de este estudio es determinar la relación entre la dependencia alcohólica y la altitud de residencia en once poblados de dos zonas altitudinales del Perú. Se realizó un estudio transversal analítico aplicando una encuesta por médicos que hasta 2013 realizaron atención primaria de salud en once poblados, que se clasificaron en zonas de baja altitud (≤ 2.500 msnm) y gran altitud (> 2.500 msnm). A los que respondieron afirmativamente a la pregunta de si consumían bebidas alcohólicas, se les aplicó el test CAGE para alcoholismo (punto de corte, ≥ 2). Con los modelos lineales generalizados, se obtuvieron los estadísticos de asociación. De los 737 participantes, el 51% eran mujeres y la mediana de edad, 36 [intervalo intercuartílico, 25-50] años 334 (45%) vivían en baja altitud y 113 (15%) tenían dependencia alcohólica. La mayor frecuencia de alcoholismo se asoció positivamente con ser de un poblado considerado como extremadamente pobre (razón de prevalencia ajustada [RPa] = 2,42; intervalo de confianza del 95%, [IC95%], 1,40-4,19); mientras que, ser mujer (RPa = 0,44; IC95%, 0,23-0,89) y residir a gran altitud (RPa = 0,15; IC95%, 0,07-0,31) se asociaron negativamente, ajustando por nueve variables sociolaborales y patológicas. Según estos datos, hay mayor frecuencia de dependencia al alcohol entre los varones, los extremadamente pobres y residentes a baja altitud. Los profesionales que realizan atención primaria y los implicados en el cuidado de la salud mental deben tomarlo en cuenta por sus implicaciones para la sociedad.

The aim of this study was to determine the association between alcohol dependence and altitude of residence in 11 villages in two high altitude areas of Peru. An analytical cross-sectional study was performed using a survey conducted by physicians in primary health care in 11 villages until 2013, that were divided into low altitude (≤2500 m asl (above sea level)), and high altitude (>2500 m asl) areas. The CAGE test for alcoholism (cut point, ≥2) was applied to those who responded positively when asked if they consumed alcohol. Statistical associations were obtained with generalised linear models Of the 737 participants, 51% were women and the median age was 36 years [interquartile range, 25-50], 334 (45%) lived at low altitude, and 113 (15%) had alcohol dependence. The highest frequency of alcoholism was positively associated with being a village considered extremely poor (Likelihood Ratio (LP) = 2.42; 95%CI, 1.40-4.19), while being female (LP = 0.44; 95%CI, 0.23-0.89) and residing at high altitude (LP = 0.15; 95%CI, 0.07-0.31) were negatively associated. These were adjusted for nine socio-occupational and pathological variables. According to these data, there is a higher frequency of alcohol dependence in being, male, extremely poor, and residing at low altitude. These results should be taken into account by professionals who work in primary care and those involved in mental health care, because of their implications in society.

A evolução do Congresso Brasileiro de Atividade Física e Saúde. Copo meio cheio ou meio vazio? / The evolution of the Brazilian Congress on Physical Activity and Health. Glass half full or half empty?

O objetivo do presente estudo foi resgatar a memória do Congresso Brasileiro de Atividade Física e Saúde (CBAFS) e descrever a evolução da participação no evento segundo localização geográfica da afiliação dos participantes, eixos de pesquisa, e tipo de estudo dos resumos apresentados. A pesquisa foi realizada nos anais das nove edições do CBAFS. Buscou-se identificar o estado (convidados nacionais) e país (convidados internacionais) de origem dos palestrantes, estado de origem do primeiro autor, delineamento de estudo e eixos de pesquisa em atividade física e saúde (em que a atividade física e/ou o comportamento sedentário são exposição ou desfecho do estudo). Os dados foram apresentados em frequências absolutas, relativas e taxas brutas por milhão de habitantes. Em todos os anos foi observada uma predominância de palestrantes e de resumos da região Sul do país, seguido das regiões Sudeste e Nordeste. Quanto aos palestrantes internacionais houve participação da América do Norte (EUA, Canadá), Europa (Portugal, França, Finlândia e Dinamarca) e Colômbia. Para o conteúdo dos resumos há predominância de delineamentos transversais sobre as consequências da atividade física/comportamento sedentário na saúde, determinantes da prática de atividade física e estudos descritivos sobre nível/tendência de atividade física. O eixo de intervenções para aumento dos níveis de atividade física e diminuição do comportamento sedentário permanecem insipientes. Conclui-se que há grande disparidade geográfica em relação aos congressistas e dificuldades em traduzir as evidências em aumento nos níveis de atividade física. Entretanto, tem sido observada uma melhora em relação a representação geográfica e crescente número de participantes.

The aim of this study was to rescue the history of the Brazilian Congress of Physical Activity and Health (CBAFS) and describe the evolution of the event according to participants' geographical location of the affiliation, research axes, and type of study presented in abstracts. The survey was conducted in annals of all nine CBAFS editions. We sought to identify the state (national guests) and country (international guests) of speakers' origin, as well as first author state, study design and research lines in physical activity and health (where physical activity and/or sedentary behavior are exhibition or study endpoint). The data were presented as absolute, relative and crude rates per million population frequencies. In all years a predominance of speakers and abstracts of the Southern region, followed by the Southeast and Northeast regions was observed. Regarding international speakers there was participation from North America (USA, Canada), Europe (Portugal, France, Finland and Denmark) and Colombia. For the content of the abstracts there was a predomination of cross-sectional designs on the physical consequences of physical activity/sedentary behavior, determinants of physical activity and level of descriptive studies on levels/trends of physical activity. The axis of interventions to increase levels of physical activity and decrease sedentary behavior remained ignored. Concluded that there is still great geographical disparity in relation to congressmen and difficulties in translating evidence into increased levels of physical activity. However, an improvement has been observed in relation to geographical representation and growing number of participants'.

Isla del Coco, on Cocos Plate, converges with Isla de San Andrés, on the Caribbean Plate, at 78mm/yr / La Isla del Coco, en la Placa de Cocos, converge con la Isla de San Andrés, en la Placa del Caribe, a 78 mm/año

Isla del Coco is the only land mass of the Cocos Plate that emerges above sea level. This makes it the only place where Cocos Plate motion can be measured using Global Navigation Satellite System (GNSS) monitoring. Global Positioning System (GPS) observations have been carried out sporadically over more than two decades on Isla del Coco, allowing precise measurement of the motion of the Cocos Plate. Recently, in May 2011, a continuous GPS station was built and instrumented at Isla del Coco, in Wafer Bay, by OVSICORI-UNA and UNAVCO, as part of the COCONet regional GNSS network. Position time series from this CGPS station (ISCO: Isla del Coco) show a steady motion of Isla del Coco at a speed of 90.9±1.5mm/yr in the N35oE direction in ITRF2008 and convergence with the Caribbean Plate at 78±1mm/yr. This result is consistent with the findings of the earliest GPS studies, and agrees within uncertainty with the estimated convergence rate of 76.4±x mm/ yr of the MORVEL plate motion model. MORVEL is based on an average over the last 780,000 years, and our result suggests that Cocos-Caribbean plate motions have been constant over that time interval.

La Isla del Coco es la única porción emergida en la placa del Coco. Esta condición la hace el único lugar donde se puede medir, usando Sistemas de Navegación Global por Satélite (GNSS), la velocidad de dicha placa. Las mediciones con GPS en la Isla del Coco se han realizado por más de dos décadas, permitiendo obtener velocidades precisas. En mayo del 2001 se instaló una estación continua de GPS en la Isla del Coco como parte, tanto de la Red Regional de GNSS COCONet, como del Sistema de Monitoreo Geodinámico de Nicoya (SISMOGENICO). Resultados de esta estación continua muestran movimiento continuo de la Isla del Coco, con respecto a ITRF2008, a una velocidad de 90.9±1.5mm/año con dirección N35oE y convergencia con la placa del Caribe a 78±1mm/año. Estas velocidades son consistentes con las obtenidas por MORVEL, un modelo geológico de velocidades de placas representativo de los últimos 780,000 años, y sugieren que la convergencia de estas placas se ha mantenido constante durante ese lapso de tiempo.

Estudio de riesgos de cáncer en barrios de la ciudad de Bahía Blanca entre 1989 al 2002 / Cancer risk analysis in several neighborhoods in Bahía Blanca city in the period 1989-2002

El objetivo de esta investigación fue determinar si la incidencia de cáncer ocurrida en las áreas cercanas al Polo Petroquímico fue mayor a la observada en el resto de la ciudad de Bahía Blanca. En mayo de 2005, debido a temores expresados por los vecinos de dichas áreas, nuestro Registro de Tumores fue convocado para llevar a cabo un estudio que aportara información calificada respecto a esta posible situación. Se calcularon y compararon las Tasas de Incidencia (razón entre el número de casos nuevos de cáncer y la población total por 100.000) en los períodos 1989-1992; 1993-1997; 1998-2002, utilizando métodos de ajuste directo e indirecto. No se encontraron diferencias estadísticamente significativas en la ocurrencia de tumores entre los barrios presumiblemente afectados y el resto de la ciudad, cuando se utilizaron técnicas directas. Utilizando técnicas de comparación indirectas se observó que el cáncer de pulmón en varones fue significativamente mayor en Ingeniero White. Esta situación podría estar vinculada con un mayor consumo de tabaco.

The aim of this research work was to determine whether the incidence of cancer in the areas close to the Petrochemical Complex was higher compared with that observed in the rest of Bahía Blanca city. Therefore, due to the fears expressed by the residents of that area, in May 2005 the Tumor Record office was asked to carry out a study in order to supply qualified information on this possible situation. Incidence rates were calculated and compared (ratio between the number of new cancer cases and total population by 100,000) for the periods 1989-1992; 1993-1997; 1998-2002 using direct and indirect adjustment methods. No statistically significant differences were found in tumor occurrence in the allegedly affected neighborhoods and the rest of the city when direct techniques were used. When using indirect comparison techniques, it was observed that lung cancer was significantly higher in males living near the Petrochemical Complex (at Ingeniero White town) Such situation could be related to smoking habits in male population.

Distribución geográfica del consumo de drogas en Costa Rica 2006 / Geographical distribution of drug use in Costa Rica 2006

Este estudio servirá de base para el desarrollo de nuevos derroteros en la profundización del análisis de información con perspectiva geográfica de amplio alcance, hacia los cuales el Instituto sobre Alcoholismo y Farmacodependencia ha puesto especial énfasis

Actualización de la distribución geográfica y ecoepidemiología de la fauna de triatominos (Reduviidae: Triatominae) en Colombia / Updated geographical distribution and ecoepidemiology of the triatomine fauna (Reduviidae: Triatominae) in Colombia

La presente publicación recopila la información de registros de triatominos y datos sobre infección natural con tripanosomátidos a nivel departamental y municipal, publicada hasta la fecha así como la reportada por los servicios departamentales de salud e institutos de investigación. Se presentan figuras elaboradas de acuerdo a la información suministrada por los registros y una clasificación de la fauna triatomínica de acuerdo a las condiciones ecoepidemiológicas del país, teniendo en cuenta la altitud como factor determinante en la distribución de estos insectos. Teniendo en cuenta la frecuencia con que se reportan en el domicilio y peridomicilio, se consideran las siguientes especies como las de mayor riesgo de transmisión en Colombia: Rhodnius prolixus, Triatoma dimidiata, Triatoma maculata y Triatoma venosa. Se resalta la importancia de la vigilancia entomológica como herramienta indispensable para reforzar las estrategias de control de la transmisión de la enfermedad de Chagas, permitiendo también la evaluación del riesgo que representan las especies de triatominos silvestres en Colombia.

Information concerning triatomine records from provinces and municipalities was accumulated— including data indicating natural infections with trypanosomatides—that has been previously published or reported by Colombian provincial health services and research institutes. Altitude appeared to be the main factor responsible for the distribution of the insects. Illustrations summarize the information provided by the above records. A triatomine fauna classification is presented that corresponds to the eco-epidemiological conditions of the country, considering altitude as the factor determining the geographical distribution of these vectors. Rhodnius prolixus, Triatoma dimidiata, Triatoma maculata and Triatoma venosa are considered the major transmission risk species in Colombia, according to the frequency in which they are reported inside dwellings and peridomiciliary areas. Entomological surveillance providess a necessary tool to reinforce the control strategies for Chagas disease. This also allows the evaluation of transmission risk that the sylvatic triatomines represent in Colombia.

Análisis espacial de la mortalidad en áreas geográficas pequeñas: el enfoque bayesiano / Mortality spatial analysis in geographic areas: the Bayesian approach

El empleo de mapas para representar algunas realidades y acontecimientos relevantes en materia de salud, proporciona probablemente una imagen más expresiva de su distribución espacial que la simple observación de datos en tablas. Mediante los mapas se puede conocer el patrón de distribución geográfica de estos sucesos, y sugerir posibles explicaciones sobre las distribuciones identificadas. Consecuentemente, la construcción y suavizado de mapas han sido objeto de recientes desarrollos metodológicos. El enfoque tradicional ha consistido en representar en los mapas las razones estandarizadas de mortalidad (REM); sin embargo, cuando el número de casos en espacios geográficos reducidos es bajo, las tasas brutas de mortalidad son muy lábiles, y su representación a través de un mapa exhibe una variación amplia y poco informativa de los patrones existentes. Los métodos bayesianos ofrecen la posibilidad de “corregir” estos mapas, para que emerjan directamente patrones que no serían visibles cuando se emplean procedimientos estadísticos clásicos. Para ilustrar y explicar más detalladamente ambos métodos se utilizaron los datos de mortalidad por accidentes en Cuba, del año 1998. Para este análisis se dividió a la población en 7 grupos de edad: 0 a 14, 15 a 24, 25 a 34, 35 a 44, 45 a 54, 55 a 64, y 65 o más años; en calidad de áreas geográficas se consideraron los 169 municipios del país. Se muestran dos mapas: uno confeccionado según los métodos tradicionales, y otro según los métodos bayesianos. En este último se observa claramente el efecto de la suavización; el patrón espacial de la mortalidad, antes difuso, permite apreciar que la mortalidad por accidentes es especialmente acusada en los municipios más desarrollados

Eumycetoma by Madurella grisea: report of the first case observed in the Southern Brazilian Region

E relatado o primeiro caso de eumicetoma por Madurella grisea ocorrido na Regiao Sul (Brasil). Alem disso, a literatura brasileira correspondente foi revisada e a distribuicao geografica deste tipo de eumicetoma e apresentada

Epidemiologic surveys of histoplasmin and paracoccidioidin sensitivity in Brazil

Esta publicacao visa a tornar acessiveis os resultados obtidos em inqueritos epidemiologicos sobre histoplasmose e paracoccidioidomicose, realizados no Brasil, atraves das reacoes intradermicas de histoplasmina e paracoccidioidina. Ela justifica-se porque os resultados aqui relacionados, em grande parte, nao foram publicados em revistas cientificas. Os resultados que conseguimos colecionar sao apresentados nas tabelas: 1-sobre histoplasmose e 2-sobre paracoccidioidomicose. Ao todo sao relacionados 88 inqueritos sobre histoplasmose e 58 sobre paracoccidioidomicose. No final da publicacao sao feitos comentarios sobre os itens a serem obedecidos em inqueritos desta natureza

Schistosomiasis mansoni in the "Baixada Ocidental Maranhense", state of Maranhao, Brazil: cross-sectional studies performed in 1987 and 1993

Realizou-se, em 1993, estudo transversal acerca da ocorrencia de esquistossomose mansoni em tres localidades da Baixada Ocidental Maranhense: Alegre (municipio de Sao Bento), Alianca (municipio de Cururupu) e Coroata II (municipio de Sao Joao Batista). Os resultados foram cotejados aos de outro estudo, efetuado nas mesmas localidades e em condicoes semelhantes, em 1987. Em ambos os estudos, salvo poucas excecoes, toda a populacao das tres localidades foi submetida a exame parasitologico de fezes, pelo metodo de Kato-Katz e a intradermorreacao para esquistossomose. Os individuos que apresentaram resultado positivo em algum desses exames foram avaliados clinicamente, por meio de exame fisico. Em 1993, ao todo, 827 pessoas foram submetidas a exame de fezes e 826 a intradermorreacao...