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3.
BMC Anesthesiol ; 24(1): 327, 2024 Sep 12.
Artigo em Inglês | MEDLINE | ID: mdl-39266994

RESUMO

STUDY OBJECTIVE: Advanced rectal cancer is a common cause of perineal pain and research on the use of radiofrequency therapy for the treatment of this pain is limited. In the present study, we aimed to compare the effectiveness and safety of conventional radiofrequency (CRF) and high-voltage long-term pulsed radiofrequency (H-PRF) of radiofrequency therapy in the management of perineal pain in advanced rectal cancer. DESIGN: Randomized, Double-Blind Controlled Trial. SETTING: Sichuan Cancer Hospital & Institute and Yanjiang District People's Hospital in Sichuan, China. PARTICIPANTS: A total of 72 patients with advanced rectal cancer experiencing perineal pain who were accepted for radiofrequency treatment. INTERVENTIONS: Patients were assigned randomly (1:1) assigned to either the group CRF or H-PRF in a double-blind trial. MEASUREMENTS AND MAIN RESULTS: The primary focus was on assessing perineal pain using numeric rating scales (NRS) scores at various time points. Secondary outcomes included the duration of maintaining a sitting position, depression scores, sleep quality, consumption of Oral Morphine Equivalent and Pregabalin, and the incidence of perineal numbness. A total of 57 patients (28 patients in the group CRF and 29 patients in the group H-PRF) were investigated. At all observation time points postoperatively, both groups of patients exhibited significant reductions in pain, enhancements in depression, improvements in sleep quality, and increased duration of sitting compared to their baseline measurements (P<0.05). During the 3 months and 6 months follow-up period, the group CRF exhibited significant reduction in pain, improvement in depression, sleep quality, and increased the time of keeping a sitting position compared with the group H-PRF (P<0.05). The consumption of oral morphine equivalent and Pregabalin as well as the incidence of perineal numbness were not significantly different between groups (P > 0.05). CONCLUSION: Our results demonstrate that application of CRF and H-PRF in ganglion impar to reduce perineal pain and improve the quality of life of patients with advanced rectal cancer is safe and effective. However, the long-term effect of CRF is better compared with that of H-PRF. TRIAL REGISTRATION: https://www.chictr.org.cn/ (ChiCTR2200061800) on 02/07/2022. This study adheres to CONSORT guidelines.


Assuntos
Períneo , Neoplasias Retais , Humanos , Método Duplo-Cego , Masculino , Feminino , Neoplasias Retais/cirurgia , Pessoa de Meia-Idade , Idoso , Tratamento por Radiofrequência Pulsada/métodos , Gânglios Simpáticos , Medição da Dor/métodos , Qualidade do Sono , Adulto
4.
Tech Coloproctol ; 28(1): 125, 2024 Sep 12.
Artigo em Inglês | MEDLINE | ID: mdl-39266778

RESUMO

A 51-year-old man with a medical history of recurrent anal carcinoma after chemoradiation underwent abdominoperineal resection in 2015. The patient presents with a bulging mass in the perineal zone, associated with pain. Physical examination and MRI during the workup reveal a large mass in the perineal region.


Assuntos
Neoplasias do Ânus , Herniorrafia , Hérnia Incisional , Períneo , Protectomia , Humanos , Masculino , Pessoa de Meia-Idade , Períneo/cirurgia , Hérnia Incisional/cirurgia , Hérnia Incisional/etiologia , Herniorrafia/métodos , Neoplasias do Ânus/cirurgia , Protectomia/métodos , Protectomia/efeitos adversos , Imageamento por Ressonância Magnética
5.
Medicine (Baltimore) ; 103(36): e39259, 2024 Sep 06.
Artigo em Inglês | MEDLINE | ID: mdl-39252301

RESUMO

We aimed to evaluate the effectiveness of transperineal ultrasound (TPUS) in diagnosing rectocele, rectal intussusception (RI), enterocele, perineal descent (PD), and cystocele in Chinese women with obstructed defecation syndrome (ODS), and to determine the grading of rectocele via TPUS. Between January 2019 and December 2021, 107 obstructed defecation syndrome patients, with a mean age of 49.76 years, received TPUS and defecation proctography (DEP). Both methods were used to diagnose anorectal angle, rectocele, RI, enterocele, and PD, while cystocele and uterine prolapse were diagnosed only through TPUS. Agreement between DEP and TPUS diagnostic results was compared using Cohen kappa statistics. Seventy-six rectoceles were reported following DEP and 72 after TPUS. DEP detected 7 enteroceles, 6 of which were diagnosed simultaneously by TPUS. 43 patients presented dyssynergic defecation (DD) upon DEP, while 51 upon TPUS. DEP and TPUS detected PD in 13 and 11 patients respectively, and RI in 82 and 73, respectively. Rectocele (kappa = 0.738), RI (kappa = 0.711), DD (kappa = 0.774), enterocele (kappa = 0.847), and PD (kappa = 0.625) were obtained by Cohen kappa statistics, which indicated a good agreement between DEP and TPUS. The cutoff values for the diagnosis of moderate and severe rectocele with TPUS were 12.05 mm (AUC: 0.941) and 18.50 mm (AUC: 0.977), respectively. The DEP-determined and TPUS-determined anorectal angles were significantly correlated in the resting and Valsalva states (P < .01). Compared with DEP, while maintaining good agreement in detecting rectocele, RI, DD, enterocele, and PD, TPUS is a repeatable and noninvasive alternative. Threshold values of 12.05 mm and 18.50 mm on TPUS may diagnose moderate and severe rectocele, respectively.


Assuntos
Constipação Intestinal , Defecação , Retocele , Ultrassonografia , Humanos , Feminino , Retocele/diagnóstico por imagem , Retocele/complicações , Pessoa de Meia-Idade , Ultrassonografia/métodos , Constipação Intestinal/diagnóstico por imagem , Constipação Intestinal/diagnóstico , Adulto , Defecação/fisiologia , China , Idoso , Defecografia/métodos , Intussuscepção/diagnóstico por imagem , Intussuscepção/diagnóstico , Períneo/diagnóstico por imagem , Síndrome , População do Leste Asiático
6.
Eur J Obstet Gynecol Reprod Biol ; 301: 240-245, 2024 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-39167877

RESUMO

INTRODUCTION: Vaginal delivery has several benefits for the parturient; however, during labor, some injuries, such as lacerations and/or episiotomy, can occur. Perineal pain may occur in the puerperium and can be aggravated in cases of perineal injury during childbirth, potentially impacting the physical and emotional aspects of the parturient. For this reason, it is necessary to use techniques that can relieve pain and edema in the immediate postpartum period, directly influencing recovery. OBJECTIVE: To compare the reduction of pain and improvement in healing using two techniques, namely photobiomodulation and cryotherapy, performed in the immediate postpartum period of up to 12 h, in parturients who suffered grade I and II lacerations and/or episiotomy. METHODS: Data collection was carried out through an evaluation questionnaire. Photobiomodulation was applied using the red and infrared laser from the DMC brand. The EVA and McGill scales were used for pain assessment, and the REEDA scale was used for the evaluation of edema and healing. RESULTS: The techniques were evaluated and applied to 56 patients, with 28 in each group (cryotherapy and LBI). Patients who received photobiomodulation showed superior improvement compared to cryotherapy. In the immediate postpartum period, there was a greater reduction in pain in favor of photobiomodulation (p = 0.008); and after 24 h, the difference was even more significant (p < 0.001).


Assuntos
Crioterapia , Edema , Episiotomia , Lacerações , Terapia com Luz de Baixa Intensidade , Períneo , Período Pós-Parto , Humanos , Feminino , Crioterapia/métodos , Períneo/lesões , Episiotomia/efeitos adversos , Adulto , Edema/prevenção & controle , Edema/terapia , Edema/etiologia , Gravidez , Lacerações/terapia , Terapia com Luz de Baixa Intensidade/métodos , Doenças da Vulva/terapia , Vulva , Adulto Jovem , Medição da Dor , Parto Obstétrico/efeitos adversos
7.
Eur J Obstet Gynecol Reprod Biol ; 301: 147-153, 2024 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-39137593

RESUMO

OBJECTIVES: To develop a deep learning (DL)-model using convolutional neural networks (CNN) to automatically identify the fetal head position at transperineal ultrasound in the second stage of labor. MATERIAL AND METHODS: Prospective, multicenter study including singleton, term, cephalic pregnancies in the second stage of labor. We assessed the fetal head position using transabdominal ultrasound and subsequently, obtained an image of the fetal head on the axial plane using transperineal ultrasound and labeled it according to the transabdominal ultrasound findings. The ultrasound images were randomly allocated into the three datasets containing a similar proportion of images of each subtype of fetal head position (occiput anterior, posterior, right and left transverse): the training dataset included 70 %, the validation dataset 15 %, and the testing dataset 15 % of the acquired images. The pre-trained ResNet18 model was employed as a foundational framework for feature extraction and classification. CNN1 was trained to differentiate between occiput anterior (OA) and non-OA positions, CNN2 classified fetal head malpositions into occiput posterior (OP) or occiput transverse (OT) position, and CNN3 classified the remaining images as right or left OT. The DL-model was constructed using three convolutional neural networks (CNN) working simultaneously for the classification of fetal head positions. The performance of the algorithm was evaluated in terms of accuracy, sensitivity, specificity, F1-score and Cohen's kappa. RESULTS: Between February 2018 and May 2023, 2154 transperineal images were included from eligible participants across 16 collaborating centers. The overall performance of the model for the classification of the fetal head position in the axial plane at transperineal ultrasound was excellent, with an of 94.5 % (95 % CI 92.0--97.0), a sensitivity of 95.6 % (95 % CI 96.8-100.0), a specificity of 91.2 % (95 % CI 87.3-95.1), a F1-score of 0.92 and a Cohen's kappa of 0.90. The best performance was achieved by the CNN1 - OA position vs fetal head malpositions - with an accuracy of 98.3 % (95 % CI 96.9-99.7), followed by CNN2 - OP vs OT positions - with an accuracy of 93.9 % (95 % CI 89.6-98.2), and finally, CNN3 - right vs left OT position - with an accuracy of 91.3 % (95 % CI 83.5-99.1). CONCLUSIONS: We have developed a DL-model capable of assessing fetal head position using transperineal ultrasound during the second stage of labor with an excellent overall accuracy. Future studies should validate our DL model using larger datasets and real-time patients before introducing it into routine clinical practice.


Assuntos
Aprendizado Profundo , Cabeça , Apresentação no Trabalho de Parto , Segunda Fase do Trabalho de Parto , Ultrassonografia Pré-Natal , Humanos , Gravidez , Feminino , Ultrassonografia Pré-Natal/métodos , Cabeça/diagnóstico por imagem , Cabeça/embriologia , Estudos Prospectivos , Adulto , Períneo/diagnóstico por imagem
8.
Arch Gynecol Obstet ; 310(4): 1997-2006, 2024 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-39164504

RESUMO

PURPOSE: The aim of our study was to assess the possible benefits of Therapeutic Magnetic Resonance (TMR) in the treatment of spontaneous perineal lacerations and episiotomies in the postpartum. METHODS: We performed a prospective, non-pharmacologic, non-profit, monocentric interventional study on women who had a spontaneous laceration and/or an episiotomy at delivery. The TMR device treatment was accepted by 52 women, while 120 women underwent standard care. Patients were visited 1 day postpartum, before starting the treatment; then a follow-up visit was performed at 3 weeks, 5 weeks, and 3 months after delivery. The main endpoint was the time required for complete healing of the laceration and/or the episiotomy. Secondary endpoints were the prevalence of dehiscence, infections, urinary discomfort, urinary leakage, and the quality of restoration of sexual function. RESULTS: In the treatment group the REEDA score was significantly better both at 3- and 5-weeks postpartum follow-up. At 3 weeks and 5 weeks postpartum, we observed a significantly better outcome in the treatment group for all subjective complaints and perineal complications associated with lacerations and episiotomies. The percentage of patients who scored above the cutoff for sexual dysfunction was significantly better in the treatment group (83.3%) than in the control group (31.8%) (p < 0.001). CONCLUSIONS: With this pilot study, we introduced low dose Pulsating Electromagnetic Fields (PEMFs) as a novel conservative and not pharmacological approach to reduce complications of perineal lesions. Our results demonstrated to significantly improve perineal wound healing and to ameliorate the sexual function in the postpartum.


Assuntos
Episiotomia , Lacerações , Períneo , Período Pós-Parto , Cicatrização , Humanos , Feminino , Períneo/lesões , Projetos Piloto , Adulto , Estudos Prospectivos , Episiotomia/efeitos adversos , Magnetoterapia/métodos , Gravidez , Adulto Jovem
10.
Rev Int Androl ; 22(2): 10-13, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-39135369

RESUMO

The treatment of male severe stress incontinence (MUI) after surgery is the implantation of an artificial urinary sphincter (AUS). Traditionally you need two incisions: perineal and inguinal. Our objetive is present a series of patients treated with the Zephyr 375 EUA implant through a single perineal incision. We present six men operated on for MUI after Transuretral resection of the prostate (TURP) (1) and radical prostatectomy (5). Preoperatively we perform Pad-Test and cystoscopy. Under epidural anesthesia, a vertical perineal incision was made and dissection up to the bulbospongiosus muscle was divided and we dissected the bulbar urethra. After removing the probe, we place the cuff, checking that it reaches the appropriate pressure, leaving it deactivated. To place the pump-reservoir, we digitally develop a scrotal dartos pocket from the perineum that we close with Vicryl 3/0. After closing the muscle with 3/0 Vicryl, we left a suction drain and a bladder catheter. The mean age was 63 years (55-72). Mean surgical time was 68 minutes (60-85). All were discharged the next day without catheter and drain. All patients comfortably palpated the scrotal reservoir-pump. After activation, all patients were continent without needing additional adjustment, using 3 a safety pad. The degree of satisfaction was very high, all of them affirmed that they would undergo the same intervention again. The Zephyr 375 urinary sphincter allows placement through a single perineal incision, reducing surgical time, simplifying the technique, and reducing morbidity without compromising the functional outcome.


Assuntos
Períneo , Prostatectomia , Incontinência Urinária por Estresse , Esfíncter Urinário Artificial , Humanos , Masculino , Pessoa de Meia-Idade , Idoso , Prostatectomia/métodos , Períneo/cirurgia , Incontinência Urinária por Estresse/cirurgia , Ressecção Transuretral da Próstata/métodos , Complicações Pós-Operatórias , Resultado do Tratamento , Implantação de Prótese/métodos , Duração da Cirurgia
11.
Medicina (Kaunas) ; 60(8)2024 Aug 05.
Artigo em Inglês | MEDLINE | ID: mdl-39202545

RESUMO

Background and Objectives: This retrospective analysis investigated the impact of preparation of the pelvic floor for childbirth with stretching balloons and perineal massage on the risk of pelvic floor injuries. Materials and Methods: We analyzed 150 primiparous women who accessed private clinics in Padua (Italy) in the period 2019-2023 regarding the rate of perineal trauma and postpartum dysfunction across three groups: the balloon stretching group (BSG, N = 50, 33.3%), the perineal massage group (PMG, N = 39, 26.0%), and the control group (CG, 61, 40.7%). Results: Prenatal perineal training had a significant impact on reducing the rate of perineal injury and episiotomy (27.5% in BSG vs. 48.7% in PMG and 68.3% in CG, p = 0.008, respectively, 9.8% vs. 26% and 40%, p = 0.046) and the duration of the second stage of labor (BSG and PMG had a shorter duration compared to CG with a mean difference of -0.97892 h, p < 0.001, respectively, -0.63372 h, p = 0.002). Patients who carry out the preparation with the stretching balloon are less likely to develop urinary and anal incontinence and pain during intercourse. Specifically, the rate of urinary incontinence in BSG stands at around 23.5% compared to 43.6% in PMG (p = 0.345) and 55% in CG (p = 0.034). Dyspareunia in BSG was detected in 11.8% of cases compared to 35.5% in PMG (p = 0.035) and 61.7% in CG (p < 0.01). Symptomatology inherent to the posterior compartment was reported in 9.8% of cases in BSG vs. 23.11% in PMG (p = 0.085) and 33.3% in CG (p = 0.03%). Conclusions: Stretching balloons and perineal massage can be chosen as tools to prevent and reduce the rates of obstetric trauma during childbirth and to reduce the use of episiotomies as well as protect against the development of dysfunctions of the pelvic floor.


Assuntos
Episiotomia , Períneo , Humanos , Feminino , Períneo/lesões , Adulto , Estudos Retrospectivos , Gravidez , Itália , Episiotomia/estatística & dados numéricos , Episiotomia/métodos , Período Pós-Parto , Diafragma da Pelve/lesões , Massagem/métodos , Massagem/normas , Parto Obstétrico/métodos , Parto Obstétrico/efeitos adversos , Seguimentos
13.
Urologie ; 63(9): 934-942, 2024 Sep.
Artigo em Alemão | MEDLINE | ID: mdl-39158686

RESUMO

The prostate biopsy is an essential tool for diagnosing prostate cancer (PCa). While transrectal biopsy (TR-Bx) continues to be considered the gold standard in Germany, the European Association of Urology (EAU) guidelines increasingly recommend transperineal biopsy (TP-Bx) due to lower infection rates and higher tumor detection rates. This article provides an overview of the history and development of the perineal biopsy, compares TR-Bx and TP-Bx and discusses the need for antibiotic prophylaxis before TP-Bx. Current studies have shown that TP-Bx can be performed without antibiotic prophylaxis and new techniques such as robotic-assisted and vector biopsy show very precise results. The establishment of TP-Bx is being promoted by extrabudgetary funding and technological advancements, with the choice of biopsy method remaining an individual decision jointly made in dialogue with the patient.


Assuntos
Períneo , Próstata , Neoplasias da Próstata , Humanos , Períneo/patologia , Masculino , Neoplasias da Próstata/patologia , Neoplasias da Próstata/diagnóstico , Próstata/patologia , Biópsia/métodos , Antibioticoprofilaxia/métodos
14.
Int Braz J Urol ; 50(5): 595-604, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39106115

RESUMO

PURPOSE: To validate the Barcelona magnetic resonance imaging predictive model (BCN-MRI PM) in men with pre-biopsy multiparametric MRI (mpMRI) reported with the Prostate Imaging Reporting and Data System (PI-RADS) v2.1, followed by transrectal and transperineal prostate biopsies. MATERIALS AND METHODS: Prospective analysis of 3,264 men with PSA >3.0 ng/mL and/or abnormal digital rectal examination who were referred to ten participant centers in the csPCa early detection program of Catalonia (Spain), between 2021 and 2023. MpMRI was reported with the PI-RADS v2.1, and 2- to 4-core MRI-transrectal ultrasound (TRUS) fusion-targeted biopsy of suspected lesions and/or 12-core systematic biopsy were conducted. 2,295 (70.3%) individuals were referred to six centers for transrectal prostate biopsies, while 969 (39.7%) were referred to four centers for transperineal prostate biopsies. CsPCa was classified whenever the International Society of Urologic Pathology grade group was 2 or higher. RESULTS: CsPCa was detected in 41% of transrectal prostate biopsies and in 45.9% of transperineal prostate biopsies (p < 0.016). Both BCN-MRI PM calibration curves were within the ideal correlation between predicted and observed csPCa. Areas under the curve and 95% confidence intervals were 0.847 (0.830-0.857) and 0.830 (0.823-0.855), respectively (p = 0.346). Specificities corresponding to 95% sensitivity were 37.6 and 36.8%, respectively (p = 0.387). The Net benefit of the BCN-MRI PM was similar with both biopsy methods. CONCLUSIONS: The BCN-MRI PM has been successfully validated when mpMRI was reported with the PI-RADS v2.1 and prostate biopsies were conducted via the transrectal and transperineal route.


Assuntos
Biópsia Guiada por Imagem , Imageamento por Ressonância Magnética Multiparamétrica , Próstata , Neoplasias da Próstata , Humanos , Masculino , Neoplasias da Próstata/patologia , Neoplasias da Próstata/diagnóstico por imagem , Estudos Prospectivos , Biópsia Guiada por Imagem/métodos , Imageamento por Ressonância Magnética Multiparamétrica/métodos , Idoso , Pessoa de Meia-Idade , Próstata/patologia , Próstata/diagnóstico por imagem , Períneo/diagnóstico por imagem , Períneo/patologia , Valor Preditivo dos Testes , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Imageamento por Ressonância Magnética/métodos
15.
Int Braz J Urol ; 50(5): 616-628, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39106117

RESUMO

PURPOSE: To compare transperineal (TP) vs transrectal (TR) magnetic resonance imaging (MRI) and transrectal ultrasound (TRUS) fusion-guided prostate biopsy (PBx) in a large, ethnically diverse and multiracial cohort. MATERIALS AND METHODS: Consecutive patients who underwent multiparametric (mp) MRI followed by TP or TR TRUS-fusion guided PBx, were identified from a prospective database (IRB #HS-13-00663). All patients underwent mpMRI followed by 12-14 core systematic PBx. A minimum of two additional target-biopsy cores were taken per PIRADS≥3 lesion. The endpoint was the detection of clinically significant prostate cancer (CSPCa; Grade Group, GG≥2). Statistical significance was defined as p<0.05. RESULTS: A total of 1491 patients met inclusion criteria, with 480 undergoing TP and 1011 TR PBx. Overall, 11% of patients were Asians, 5% African Americans, 14% Hispanic, 14% Others, and 56% White, similar between TP and TR (p=0.4). For PIRADS 3-5, the TP PBx CSPCa detection was significantly higher (61% vs 54%, p=0.03) than TR PBx, but not for PIRADS 1-2 (13% vs 13%, p=1.0). After adjusting for confounders on multivariable analysis, Black race, but not the PBx approach (TP vs TR), was an independent predictor of CSPCa detection. The median maximum cancer core length (11 vs 8mm; p<0.001) and percent (80% vs 60%; p<0.001) were greater for TP PBx even after adjusting for confounders. CONCLUSIONS: In a large and diverse cohort, Black race, but not the biopsy approach, was an independent predictor for CSPCa detection. TP and TR PBx yielded similar CSPCa detection rates; however the TP PBx was histologically more informative.


Assuntos
Biópsia Guiada por Imagem , Próstata , Neoplasias da Próstata , Ultrassonografia de Intervenção , Humanos , Masculino , Neoplasias da Próstata/patologia , Neoplasias da Próstata/diagnóstico por imagem , Biópsia Guiada por Imagem/métodos , Pessoa de Meia-Idade , Idoso , Ultrassonografia de Intervenção/métodos , Próstata/patologia , Próstata/diagnóstico por imagem , Períneo , Imagem por Ressonância Magnética Intervencionista/métodos , Gradação de Tumores , Imageamento por Ressonância Magnética Multiparamétrica/métodos , Reprodutibilidade dos Testes
16.
PLoS One ; 19(8): e0305048, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39088486

RESUMO

BACKGROUND AND OBJECTIVE: Episiotomy is one of the most commonly performed procedures in obstetrics. complications of episiotomy are pain, bleeding, infection, pain in the sitting position, and difficulty in taking care of the baby. This study aimed to investigate the effect of Camellia sinensis ointment on perineal pain and episiotomy wound healing in primiparous women. METHODS: This triple-blinded randomized clinical trial was conducted on 60 primiparous women who were referred to the maternity ward of Al-Hadi hospital in Shoushtar and Ganjovian hospital in Dezful, Iran, from 2020 to 2021. Participants were randomly assigned into two groups of intervention (Camellia sinensis extract ointment) and control (placebo) with a follow-up of 14 days. REEDA scale (redness, edema, ecchymosis, discharge, and approximation) was used to measure wound healing and the Visual Analog Scale (VAS) was used to measure the pain intensity. RESULTS: There was no significant difference between two groups before intervention in terms of sociodemographic characteristics, pain intensity, and episiotomy wound status. Scores of pain intensity and wound healing reduced on days 7, 10, and 14 post-intervention in the intervention group compared to placebo. There was a significant decrease between the groups of intervention and control in terms of the mean score of pain intensity (VAS scale) on day 10 (1.33 ± 0.71, 1.77 ± 0.93) and day 14 (0.73 ± 0.74, 1.13 ± 0.81) post-intervention (P < 0.05). Also, on day 14 post-intervention, there was a significant decrease between the groups of intervention and control in terms of the mean score of episiotomy wound healing (REEDA index) (0.53 ± 0.77, 1.77 ± 1.46) (P < 0.05). The GLM test was applied for repeated measures. REEDA index and VAS scale changed during different times (time-variable) (p < .001). But, the studied groups (group variable) and the studied groups (interaction effect of group * time) did not affect the changes in the REEDA index (p = .292, p = .306) and VAS scale (p = .47) during different times. CONCLUSION: Our study showed that Camellia sinensis extract ointment has a small effect on the healing process and pain reduction of episiotomy wounds. to confirm its effect, a study with a larger sample size should be conducted. TRIAL REGISTRATION: This trial was registered in the Iranian Registry of Clinical Trials on 04/10/2019 with the IRCT ID: IRCT20190804044428N1. Participants were enrolled between 11 April 2020 and 20 January 2021. URL of registry: https://en.irct.ir/trial/41326.


Assuntos
Camellia sinensis , Episiotomia , Pomadas , Períneo , Cicatrização , Humanos , Feminino , Episiotomia/efeitos adversos , Adulto , Cicatrização/efeitos dos fármacos , Períneo/lesões , Gravidez , Camellia sinensis/química , Adulto Jovem , Extratos Vegetais/farmacologia , Extratos Vegetais/administração & dosagem , Extratos Vegetais/uso terapêutico , Medição da Dor , Paridade , Dor Pós-Operatória/tratamento farmacológico , Dor/tratamento farmacológico , Irã (Geográfico)
17.
Afr J Reprod Health ; 28(7): 35-46, 2024 Jul 31.
Artigo em Inglês | MEDLINE | ID: mdl-39097970

RESUMO

Energy therapies are complementary methods focused on revealing the existing energy and restoring the individual's (recipient's) energy. The aim of this study was to investigate the impact of Reiki practice applied to postpartum women who had spontaneous childbirth without instrumental delivery on postpartum episiotomy recovery and perineal pain. The research was randomized controlled at a hospital in pre-test post-test design. 86 postpartum women in total were included in the research, (n=40) in intervention group and (n=46) in control group. On the postpartum 1st day, 2nd day, 7th day and 14th day, episiotomy recovery of the intervention and control group was assessed with REEDA Scale and perineal pain was assessed with Short Form McGill Pain Questionnaire. The tree sessions of Reiki for 35-40 minutes were applied to intervention group on the postpartum 1st day, 2nd day and 7th day. (Clinical Trial Registry and Registration Number: NCT05486624). The REEDA Scale average oedema scores of the control group postpartum women were higher than intervention group. The control group had higher pain average than the intervention group. The Reiki applied to postpartum women who had spontaneous childbirth without instrumental delivery had a positive impact on episiotomy recovery due to its impact on oedema and it reduced perineal pain.


Les thérapies énergétiques sont des méthodes complémentaires axées sur la révélation de l'énergie existante et la restauration de l'énergie de l'individu (du destinataire). Le but de cette étude était d'étudier l'impact de la pratique du Reiki appliquée aux femmes en post-partum ayant eu un accouchement spontané sans accouchement instrumental sur la récupération par épisiotomie post-partum et les douleurs périnéales. La recherche a été randomisée et contrôlée dans un hôpital selon une conception pré-test et post-test. Au total, 86 femmes en post-partum ont été incluses dans la recherche, (n = 40) dans le groupe d'intervention et (n = 46) dans le groupe témoin. Les 1er, 2e, 7e et 14e jours post-partum, la récupération par épisiotomie du groupe d'intervention et du groupe témoin a été évaluée avec l'échelle REEDA et la douleur périnéale a été évaluée avec le questionnaire abrégé sur la douleur de McGill. Les séances d'arbres de Reiki pendant 35 à 40 minutes ont été appliquées au groupe d'intervention les 1er, 2e et 7e jours post-partum. (Registre des essais cliniques et numéro d'enregistrement : NCT05486624). Les scores moyens d'œdème sur l'échelle REEDA des femmes en post-partum du groupe témoin étaient plus élevés que ceux du groupe d'intervention. Le groupe témoin présentait une douleur moyenne plus élevée que le groupe d'intervention. Le Reiki appliqué aux femmes en post-partum ayant eu un accouchement spontané sans accouchement instrumental a eu un impact positif sur la récupération par épisiotomie en raison de son impact sur l'œdème et de la réduction des douleurs périnéales.


Assuntos
Episiotomia , Medição da Dor , Períneo , Período Pós-Parto , Toque Terapêutico , Humanos , Episiotomia/efeitos adversos , Feminino , Adulto , Períneo/lesões , Gravidez , Toque Terapêutico/métodos , Manejo da Dor/métodos , Parto Obstétrico/efeitos adversos , Resultado do Tratamento
18.
Handchir Mikrochir Plast Chir ; 56(4): 269-278, 2024 Aug.
Artigo em Alemão | MEDLINE | ID: mdl-39137788

RESUMO

The surgical-oncological treatment of pelvic and perineal malignancies is associated with a high complication rate and morbidity for patients. Modern multimodal treatment modalities, such as neoadjuvant radio-chemotherapy for anal or rectal cancer, increase the long-term survival rate while reducing the risk of local recurrence. Simultaneously, the increasing surgical radicality and higher oncological safety with wide resection margins is inevitably associated with larger and, due to radiation, more complex tissue defects in the perineal and sacral parts of the pelvic floor. Therefore, the plastic-surgical reconstruction of complex pelvic-perineal defects following oncological resection remains challenging. The reconstructive armamentarium, and thus the treatment of such defects, is broad and ranges from local, regional and muscle-based flaps to microvascular and perforator-based procedures. While the use of flaps is associated with a significant, well-documented reduction in postoperative complications compared to primary closure, there is still a lack of reliable data directly comparing the postoperative results of different reconstructive approaches. Additionaly, the current data shows that the quality of life of these patients is rarely recorded in a standardised manner. In a consensus workshop at the 44th annual meeting of the German-speaking Association for Microsurgery on the topic of "Reconstruction of oncological defects in the pelvic-perineal area", the current literature was discussed and recommendations for the reconstruction of complex defects in this area were developed. The aim of this workshop was to identify knowledge gaps and establish an expert consensus to ensure and continuously improve the quality of reconstruction in this challenging area. In addition, the importance of the "patient-reported outcome measures" in pelvic reconstruction was highlighted, and the commitment to its widespread use in the era of value-based healthcare was affirmed.


Assuntos
Períneo , Procedimentos de Cirurgia Plástica , Humanos , Procedimentos de Cirurgia Plástica/métodos , Períneo/cirurgia , Neoplasias Pélvicas/cirurgia , Neoplasias Retais/cirurgia , Retalhos Cirúrgicos/cirurgia , Terapia Combinada , Complicações Pós-Operatórias/etiologia , Microcirurgia
19.
BMC Pregnancy Childbirth ; 24(1): 539, 2024 Aug 14.
Artigo em Inglês | MEDLINE | ID: mdl-39143527

RESUMO

BACKGROUND: Incidence of complications following obstetrical anal sphincter injury (OASI) during vaginal delivery are poorly defined. They are only studied in high level maternities, small cohorts, all stages of perineal tear or in low-income countries. The aim of our study was to describe complications after primary OASI repair following a vaginal delivery in all French maternity wards at short and midterm and to assess factors associated with complication occurrence. METHODS: We conducted a historical cohort study using the French nationwide claim database (PMSI) from January 2013 to December 2021. All women who sustained an OASI repair following a vaginal delivery were included and virtually followed-up for 2 years. Then, we searched for OASIS complications. Finally, we evaluated factors associated with OASIS complication repaired or not and OASIS complication repairs. RESULTS: Among the 61,833 included women, 2015 (2.8%) had an OASI complication and 842 (1.16%) underwent an OASI complication repair. Women were mainly primiparous (71.6%) and 44.3% underwent an instrumental delivery. During a follow-up of 2 years, 0.6% (n = 463), 0.3% (n = 240), 0.2% (n = 176), 0.1% (n = 84), 0.06% (n = 43) and 0.01% (n = 5) of patients underwent second surgery for a perineal repair, a fistula repair, a sphincteroplasty, a perineal infection, a colostomy and a sacral nervous anal stimulation, respectively. Only one case of artificial anal sphincter was noticed. Instrumental deliveries (OR = 1.56 CI95%[1.29;1.9]), private for-profit hospitals (OR = 1.42 [1.11;1.82], reference group "public hospital"), obesity (OR = 1.36 [1;1.84]), stage IV OASIS (OR = 2.98 [2.4;3.72]), perineal wound breakdown (OR = 2.8 [1.4;5.48]), ages between 25 and 29 years old (OR = 1.59 [1.17;2.18], refence group "age between 13 and 24 years old") and 30 and 34 years old (OR = 1.57 [1.14; 2.16], refence group "age between 13 and 24 years old") were factors associated with OASIS complication repairs. CONCLUSIONS: Maternal age, stage IV OASIS, obesity, instrumental deliveries and private for-profit hospitals seemed to predict OASIS complications. Understanding factors associated with OASIS complications could be beneficial for the patient to inform them and to influence the patient's follow-up in order to prevent complications, repairs and maternal distress.


Assuntos
Canal Anal , Parto Obstétrico , Complicações do Trabalho de Parto , Humanos , Feminino , Canal Anal/lesões , Canal Anal/cirurgia , França/epidemiologia , Gravidez , Adulto , Parto Obstétrico/efeitos adversos , Parto Obstétrico/estatística & dados numéricos , Complicações do Trabalho de Parto/epidemiologia , Complicações do Trabalho de Parto/etiologia , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Períneo/lesões , Períneo/cirurgia , Estudos de Coortes , Adulto Jovem , Lacerações/etiologia , Lacerações/epidemiologia , Lacerações/cirurgia , Fatores de Risco , Incidência
20.
Radiat Oncol ; 19(1): 100, 2024 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-39090614

RESUMO

BACKGROUND: We report the results of a retrospective analysis of localized prostate cancer (LPCa) treated with transperineal ultrasound image-guided radiotherapy (TPUS-IGRT). METHODS: A total of 124 patients (median age: 74 y, 46-84 y) with LPCa who underwent TPUS-IGRT (Clarity Autoscan system; CAS, Elekta; Stockholm, Sweden) between April 2016 and October 2021 for curative/after hormone induction were enrolled. The number of patients by risk (National Comprehensive Cancer Network 2019) was 7, 25, 42, and 50 for low (LR), good intermediate (good IR), poor intermediate (poor IR), and high (HR)/very high (VHR), respectively. Ninety-five patients were given neoadjuvant hormonal therapy. The planning target volume margin setting was 3 mm for rectal in most cases, 5-7 mm for superior/inferior, and 5 mm for anterior/right/left. The principle prescribed dose is 74 Gy (LR), 76 Gy (good IR), and 76-78 Gy (poor IR or above). CAS was equipped with a real-time prostate intrafraction monitoring (RTPIFM) system. When a displacement of 2-3 mm or more was detected, irradiation was paused, and the patients were placed on standby for prostate reinstatement/recorrection. Of the 3135 fractions in 85 patients for whom RTPIFM was performed, 1008 fractions (32.1%) were recorrected at least once after starting irradiation. RESULTS: A total of 123 patients completed the radiotherapy course. The 5-year overall survival rate was 95.9%. The 5-year biological prostate-specific antigen relapse-free survival rate (bPFS) was 100% for LR, 92.9% for intermediate IR, and 93.2% for HR/VHR (Phoenix method). The 5-year late toxicity rate of Grade 2+ was 7.4% for genitourinary (GU) and 6.5% for gastrointestinal (GI) organs. Comparing the ≤ 76 Gy group to the 78 Gy group for both GU and GI organs, the incidence was higher in the 78 Gy group for both groups. CONCLUSION: These results suggest that TPUS-IGRT is well tolerated, as the bPFS and incidence of late toxicity are almost comparable to those reported by other sources of image-guided radiotherapy.


Assuntos
Neoplasias da Próstata , Radioterapia Guiada por Imagem , Humanos , Masculino , Neoplasias da Próstata/radioterapia , Neoplasias da Próstata/patologia , Neoplasias da Próstata/diagnóstico por imagem , Idoso , Radioterapia Guiada por Imagem/métodos , Estudos Retrospectivos , Idoso de 80 Anos ou mais , Pessoa de Meia-Idade , Resultado do Tratamento , Dosagem Radioterapêutica , Radioterapia de Intensidade Modulada/métodos , Períneo , Planejamento da Radioterapia Assistida por Computador/métodos
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