Anaphylactoid reactions in Barbados: incidence, prevention and treatment

A retrospective study was done of anaphylactoid reactions occurring in Barbados up to the end of 1962. Ninety-two reactions were reported by 42 doctors, and nearly 50 percent of those reported occurred in the 5 year ending in 1962. There were 5 fatal reactions. Penicillin was the commonest cause followed by ATS and other antisera. For the established anaphylactoid reaction. Adrenalin appears to be still by far the most effective remedy. The initial dose od Adrenalin by any route should be not more than 0.3 mgm. When by the mouth to mouth method with or without oxygen, combined with prompt external cardiac massage may prevent a fatal outcome (AU)