RESUMO
Skin manifestations are a common feature of HTLV-1 associated disorders and of HTLV-1 infection itself. These include the lymphomatous skin infiltrates in adult T-cell lymphoma/leukaemia, most commonly manifesting as persistent, generalised papules, nodules and plaques with later ulceration, acquired ichthyosis and xeroderma in HAM/TSP, infective dermatitis of children, dermatomyositis, crusted (Norwegian) scabies, psoriasiform rashes which may precede one of the more serious disease associations, and possibly also seborrhoeic dermatitis. Disorders typically associated with immunosuppression such as disseminated herpes zoster, and ulcerative non-healing herpes simplex may also be seen occasionally both in ATK as well as in other wise asymptomatic HTLV-1 infection (AU)
Assuntos
Humanos , Masculino , Feminino , Criança , Adulto , Vírus Linfotrópico T Tipo 1 Humano , Linfoma Cutâneo de Células T , Dermatite , Dermatomiosite , Escabiose , Psoríase , Herpes Zoster , Herpes Simples , Leucemia-Linfoma de Células T do Adulto , Paraparesia Espástica Tropical , Uveíte , Hipercalcemia , Anemia , Complexo Relacionado com a AIDS , Hanseníase , Sarcoidose , Dermatite Esfoliativa , Escleroderma Sistêmico , Dermatopatias Vesiculobolhosas , Eczema , Ictiose , Imunoglobulina G , Anticorpos Anti-HTLV-I , Staphylococcus , Streptococcus , Bronquiectasia , Catarata , Polimiosite , Eritema , Edema , Sarcoptes scabiei , Dermatite Seborreica , Tinha do Couro Cabeludo , Região do Caribe , Estados Unidos , Haiti , Japão , América do Sul , ÁfricaRESUMO
En-plaque sarcoidosis is reported in a 74-year-old black woman. The diagnosis was made at autopsy. The patient also had adenocarcinoma of the sigmoid colon with liver metastases. Subdural sarcoidosis is very rare in that only four cases have been previously reported, all of which were diagnosed clinically and treated (AU)
Assuntos
Idoso , Feminino , Humanos , Encefalopatias/patologia , Sarcoidose/patologia , JamaicaAssuntos
Humanos , Hipercalcemia/etiologia , Hipercalcemia/patologia , Alcalose/complicações , Calcinose/complicações , /intoxicação , Inibidores de Simportadores de Cloreto de Sódio/farmacologia , Hipercalcemia/sangue , Hipercalcemia/fisiopatologia , Hiperparatireoidismo/complicações , Lítio/efeitos adversos , Osteíte Deformante/complicações , Sarcoidose/complicações , Tamoxifeno/efeitos adversos , Tretinoína/efeitos adversos , Vitamina A/toxicidadeRESUMO
The records of 91 patients who conformed to rigid criteria for the diagnosis of sarcoidosis were studied. These included 36 patients of West Indian and 47 of Caucasian origin. Comparison of these two groups showed a significantly later age of onset in the West Indians, who were also more liable to present with respiratory symptoms, particulary chest discomfort, to have eye involvement and palpable lymphadenopathy and to have a more disseminated disease than the Caucasian group. However, Caucasians were far more likely to have erythema nodosum. There was a tendency for the onset of symtoms in the whole group to occur between November to February. Differences in sarcoidosis between ethnic groups within the same geographicl area suggest variable host responses which may be dependant on their immunological response. The later age of onset of sarcoidosis seen in the West Indians might be explained by their later exposure to an environmental transmissible agent (AU)
Assuntos
Humanos , Adulto , Masculino , Feminino , Etnicidade , Sarcoidose/epidemiologia , Fatores Etários , Eritema Nodoso/etiologia , Londres , Sarcoidose/diagnóstico , Índias Ocidentais/etnologiaAssuntos
Humanos , Adulto , Feminino , Hanseníase/diagnóstico , Sarcoidose/diagnóstico , Diagnóstico Diferencial , Jamaica , Estados UnidosRESUMO
Sarcoidosis is reportedly rare in the West Indies, yet among West Indian immigrants in London the disease has been frequently found. Over the past 10 years there have been 22 histologically proven cases of sarcoidosis at the University Hospital of the West Indies, Jamaica and a review of these cases was presented. The clinical picture differed in several aspects from that reported in other communities. Extrapulmonary lesions were common, and spontaneous remissions were exceedingly rare (AU)