Rontgenpatologi i Vastindien / Roentgen pathology in the West Indies

Roentgen pathology in Jamaica includes, inter alia, skeletal changes caused by avitaminoses, infectious diseases such as syphillis or tuberculosis, and sickle cell anemia. This form of anaemia may produce also renal papillary necrosis. Worm infection with stronglyoides stercoralis causes extensive inflammatory changes in the small bowel. Malformations of the urinary tract and bones are relatively common. (AU)

Studies on protein metabolism in rats fed a tropical diet

This thesis is an account of investigations in which a special diet was fed to rats and the resulting effects on protein metabolism studied. The special diet closely resembled a type of diet consumed by poorer Jamaicans; similar diets are implicated in the protein malnutrition common in tropical areas. Rats fed this special diet were compared with others consuming adequate amounts of all the known essential nutrients. It was shown that the special diet was deficient in protein of good nutritional quality, and also in certain vitamins and minerals. The protein deficiency was chiefly responsible for the growth failure observed. The diet induced an increased susceptibility to Hypoglycin A, a toxic principle derived from the fruit of Blighia sapida. It appeared likely that this was a result of depressed gluconeogenesis. Liver and kidney, but not heart, were found to be depleted of protein. In liver, protein of varying sulphur content appeared equally affected. Serum albumin and globulin were both reduced, with no change in ratio. Respiration rates of tissue slices remained normal. The protein depletion in liver was accompanied by a parallel decrease in succinic dehydrogenase enzyme. Methionine containing radioactive sulphur was used to observe the rates of protein synthesis in tissue of animals fed the special diet. Experiments "in vitro" with liver slices gave inconclusive results, but experiments "in vivo" showed that synthesis of liver, serum and kidney protein was depressed, while that of heart protein was normal. Radioactive measurements on urine and on the non-protein fraction of serum supported the conclusion that protein synthesis was depressed in rats fed the special diet. It appeared that the major effect of the special diet was to decrease the rate of protein synthesis in the animals, the result being most apparent in tissues normally containing appreciable stores of labile protein (AU)

Report on the physical development and health of a sample of school children in the island of Leguan, British Guiana, 1941

A sample of 352 children belonging to the East Indian and Black races has been examined and the findings compared with (1) The reported Findings of a survey carried out by Dr. F. G. Rose; (2) Data obtained from Medical Inspection of Queen's College boys in 1938; (3) Weights for English boys and girls at various ages in the general population as found by the Anthropometric Commitee Investigation and quoted from Dr. Rose's report; (4) Average heights for English boys and girls of various ages as recorded by Tuxford and Glegg and quoted from Dr. Rose's report; (5) Results of a survey of school boys in Calcutta and Punjab by Wilson, Ahmad and Mitra in 1936; (6) Results from examination of school children in South India by Aykroyd and Krishman in 1936. ( 5 and 6 from Indian Journal Medical Research 24, 3 ). The survey carried out in Leguan involved a comparatively small sample and the findings must be taken as a general impression (Summary)

Transketolase in blood

In subjects suffering from vitamin deficiency, the transketolase content of the red cells was measured and the effect of thiamine pyrophosphate addition in vitro also studied. The results of these determination and details of a recommended routine method was presented (AU)