Assuntos
Humanos , Lactente , Pré-Escolar , gama-Globulinas/administração & dosagem , Imunização Passiva , Esquistossomose/prevenção & controle , Schistosoma mansoni , Ensaios Clínicos como Assunto , Fezes , Imunidade Materno-Adquirida , Imunoglobulinas/administração & dosagem , Contagem de Ovos de ParasitasRESUMO
Serum IgG concentration was lower in Jamaicans than in Nigerians. The maternal foetal IgG ratio was lower in Jamaican sera than in Nigerian sera. It is suggested that endemic malaria in Nigeria may be responsible for these differences. The higher IgG concentration in the Nigerian cord sera may be further evidence of this. Eighteen new cases of myeloma were detected in Jamaicans between August 1966 and May 1967. Based on Gm typing, only two of these showed evidence of mixed white ancestry. All others had the typical Gm groups of Negroes. Similarly, only two patients out of a total of 17 with malignant lymphoma showed evidence of mixed white ancestry. Twelve of the patients with myeloma showed serum proteins of the IgG type, five were IgA, and one had only light chains in the serum. The majority of the patients had myeloma protein of the kappa type. The Gm typing suggested that six patients had myeloma protein of the y1 heavy chain subclass, and one patient had a y3 subclass heavy chain, the remainder belonging most likely to the y2 heavy chain subclass since y2 occurs about four times as frequently as y4.
Assuntos
Humanos , Pessoa de Meia-Idade , Idoso , Masculino , Feminino , gama-Globulinas/análise , Linfoma/imunologia , Mieloma Múltiplo/imunologia , Proteína de Bence Jones/análise , Feto , Imunoglobulina G/análise , Imunoglobulina M/análise , Jamaica , Malária/imunologia , Nigéria , Negro ou Afro-AmericanoRESUMO
It is widely claimed that people living in the tropics, particularly negroes, have higher gamma globulin levels than Europeans. No such difference was found in a series of healthy Jamaicans and of healthy Europeans recently arrived in Jamaica. The zinc sulphate turbidity test does not measure gamma globulins alone (AU)
Assuntos
Humanos , Adulto , Masculino , Feminino , Técnicas In Vitro , gama-Globulinas/análise , Proteínas Sanguíneas/análise , Eletroforese em Papel/métodos , JamaicaRESUMO
It is widely claimed that persons living in the tropics, particularly negroes, have higher gamma-globulin levels than caucasians living in more temperate climates. In an investigation at the U.C.W.I., Jamaica no difference has been found to exist between the gamma-globulin levels of health Jamaicans and Europeans who have recently arrived in Jamaica. There is, however a statistically significant difference in the gamma-globulin levels in Jamaicans between those that are in good health and those with chronic infections (AU)
