RESUMO
An incidental finding led to a more detailed study of the effect of fever on iron absorption. The absorption of 59Fe-labelled ferrous ascorbate was measured by whole-body counting in nineteen malnourished Jamaican infants and young children. Tests were done at various stages of refeeding, and it was found that the presence of a febrile illness or the febrile response to diptheria-pertussis-tetanus immunisation profoundly depressed iron absorption. This effect was not related to the nutritional state of the patient. Recurrent minor febrile illnesses are common in this group of children and may contribute to the production of iron deficiency.(Summary)
Assuntos
Humanos , Lactente , Masculino , Feminino , Deficiências Nutricionais/metabolismo , Febre/metabolismo , Absorção Intestinal , Ferro/metabolismo , Anemia Hipocrômica/etiologia , Ácido Ascórbico , Vacinas Bacterianas , Peso Corporal , Exame de Medula Óssea , Deficiências Nutricionais/etiologia , Febre/complicações , Ferro/sangue , Isótopos de Ferro , Jamaica , Kwashiorkor/metabolismo , Vacina contra Coqueluche , RadiometriaRESUMO
The gamma-emitting amino acid [75Se]selenomethionine was given to rats and to human infants, and the rate and route of excertion of 75Se was followed for several weeks by daily measurements in a 4 pi whole body counter. These data were used to calculate the turnover rate of total body protein, and the results were checked against other, technically more difficult, methods.(AU)
Assuntos
Humanos , Lactente , Ratos , 21003 , Masculino , Metionina/metabolismo , Selênio/metabolismo , Proteínas Alimentares/metabolismo , Proteínas Sanguíneas , Fezes/análise , Glicina/metabolismo , Metionina/urina , Proteínas Musculares/metabolismo , Radioisótopos , Radiometria , Selênio/urinaAssuntos
Ratos , 21003 , Lisina/metabolismo , Deficiência de Proteína/metabolismo , Proteínas/biossíntese , Análise Química do Sangue , Isótopos de Carbono , Cloretos/análise , Injeções Intraperitoneais , Fígado/metabolismo , Lisina/análise , Músculos/metabolismo , Nitrogênio/análise , Radiometria , Pele/metabolismoRESUMO
The performance and calibration of a Packard whole body counter is described in detail. With this instrument it is possible to measure the total amount of potassium in a child of 5 kg. with an accuracy of 5 per cent in one hour. The normal potassium for a child of 1 year is 46ñ4 mEq./kg. Severely malnourished oedematous children may fall as low as 20 mEq./kg. Treatment of potassium deficiency is discussed (AU)