Posicionamento do INCA acerca do aspartame

Posicionamento do INCA acerca do aspartame, a partir da classificação da substância pela Iarc como possivelmente cancerígena para humanos

Por que devemos aumentar a tributação de bebidas alcoólicas?

Considerando que as bebidas alcóolicas causam ao menos oito tipos de câncer e que não há limite seguro de consumo, promover a taxação e política de preços tem potencial de reduzir o consumo dessas bebidas.

Carnes processadas: por que tributar?

Assim como o tabaco, as carnes processadas - salsichas, linguiças, mortadelas, dentre outras - causam câncer e não existe limite seguro de consumo. Assim, promover a taxação e política de preços tem potencial para reduzir o consumo dessas carnes processadas.

INCA e Iarc lançam centro de aprendizagem regional

O INCA e a Agência Internacional de Pesquisa sobre o Câncer (Iarc) estão criando o Centro de Aprendizagem Iarc-Brasil para aprimorar as habilidades de pesquisadores e profissionais, além de promover pesquisas e atividades colaborativas de prevenção e controle do câncer no Brasil e na América do Sul, além dos países de baixa e média renda de língua portuguesa. O termo de cooperação para a criação do Centro foi assinado dia 16 de maio, na Iarc, em Lyon, na França. O objetivo é promover pesquisa e colaboração no controle do câncer no Brasil, na América Latina e nos países de língua portuguesa de baixa e média rendas

Relationship between children's and maternal nutrition and diet in the first 1,000 days of a child’slife and the risk of childhood cancer: Ascopingreview

Objective: The objective of this scoping review is to understand the extent and type of evidence concerning the relationship between children's and maternal nutrition and diet in the first 1,000 days of a child's life and the risk of childhood cancer. Introduction: Childhood cancer is considered rare compared to tumors that affect adults. However, its origin is not well established, and modifiable risk factors must be analyzed. Children's and maternal dietary and nutritional exposures in the first thousand days of a child's life may be significant risk predictors. Inclusion criteria: The population is the children and adolescents diagnosed with cancer (0-19 years old). The concept is the children's and maternal nutrition and diet in the first 1,000 days of a child's life. The context is the risk of childhood cancer. Methods: The scoping review will follow the Joanna Briggs Institute Manual for Scoping Review and the PRISMA Extension for Scoping Review. Cohort and case-control studies published in PubMed/Medline, LILACS, Embase, and Scopus will be included with no restrictions on the year of publication or the language. Other articles will be identified using three artificial intelligence tools. The results will be presented using a narrative synthesis and results mapping

Relationship between nutritional and dietary factors and the risk of recurrence or new primary tumors in survivors of pediatric and adolescent cancer: A scoping review

Objective: This scoping review aims to map the dietary and nutritional risk factors that in-creasetheriskofrecurrenceoranewprimarytumorinsurvivorsofpediatricandado-lescent cancer. Introduction: Pediatric and adolescent cancer survivors are more likely to recurrence or develop a new primary tumor. Diet and nutrition play a nessential role in favoring this scenario. Inclusion criteria: We will guide the research question by the PCC (population, concept, and context) strategy, adapted from the Joanna Briggs Institute (JBI) Manual. The population is survivors of pediatric and adolescent cancer, the concept is dietary and nutritional risk factors, and the context is recurrence or new primary tumors. Wewill include cohort and case-control studies. Methods: We will conduct a scoping review following the PRISMA-ScR checklist using the ayyansoftwareandMicrosoftExcel.WewillincludestudiespublishedinPubmed/Medline and Embase with no publication year or language restriction

ANPDB - African Natural Products Database

The African Natural Products Database (ANPDB) is a collection of natural product databases from various regions of Africa, it is a repository of natural products (NPs) isolated from native African organisms. It consists of the Northern African Natural Products Database (NANPDB) and the Eastern African Natural Products Database (EANPDB), covering data from 1962 to 2019. The information is derived from mainstream natural product journals as well as MSc and PhD theses from African universities. The database contains data compounds isolated from source organisms, primarily plants, but also microorganisms, animals, and marine sources. In addition to the names and molecular structures of compounds, ANPDB provides details about source organisms, biological activities (such as antimalarial, anticancer, and cytotoxic effects), modes of action (when available), and references.

APD3 - Antimicrobial Peptide Database

Antimicrobial Peptide Database (APD) is a database system dedicated to discovery timeline, glossary, nomenclature, classification, structure, function, information search, prediction, design, statistics and tools of AMPs. The peptide data stored in this original database were gleaned from the literature. Among the natural AMPs with know antimicrobial activity, there are human host defense peptides, from mammals annotated, active peptides from amphibians ( from frogs and toads), fish peptides, reptile peptides, birds, arthropods, insects, crustaceans, myriapods, chelicerata, spiders, scorpions, molluscs, AMPs from protozoa.

Chinese Medicinal Material Images Database

The Chinese Medicinal Material Images Database is database documents crude drugs commonly used in Chinese medicine practice, providing drug information, including source, origins, description, quality, taste, and clinical indications. Annotatet high quality photographs are used to illustrate and identify the key properties and selected microstructured of the drugs.

Chinese Medicine Formulae Images Database

The Chinese Medicine Formulae Images Database is database documents Chinese Medicine formulae commonly used in Chinese medical practice, which were systematically consolidated and summarized in the form of images and detailed description. It provides formula composition, processing forms, function, indications and usage, along with formula song and shortland methods. The database was developed as a teaching and learning platform for the subject of Traditional Chinese Medicine formulae.

Chinese Medicine Specimen Database

The Chinese Medicine Specimen Database by HKBU offers detailed information on traditional Chinese medicinal specimens. It contains a collection of data on herbal medicines, including their physical attributes, origins, and usage in traditional Chinese medicine practices

GPGD - Global Pharmacopoeia Genome Database

The World Pharmacopoeia Genome Database Project aim to generate genomics data for herb species from Pharmacopoeias of China, USA, Europe, Japan, Korea, India, Iran, Egypt and Brazil. The goal of GPGD is to realize the open-access and sharing of herb genomics data, to promote the data utilization in decomposition of biosynthesis and regulation mechanisms of key secondary metabolites, and finally to accelerate breeding of superior cultivars. Based on the previous research results of the herbgenomics team, the data including genome, transcriptome, superbarcode and DNA barcode along with abundant newly generated data were arranged and combined to build the database. GPGD, aimed to collect genomic resources of medicinal species from major pharmacopoeias worldwide and other related species.

ITCM - Integrated Traditional Chinese Medicine

Integrated Traditional Chinese Medicine (ITCM) is a database collects and analyze the largest uniform high-throughput sequencing datasets, including high-quality pharmacological transcription profiles of active TCM ingredients. Notably, profiles of of TCM ingredients were firstly obtained.

MMDBD - Medicinal Materials DNA Barcode Database

Medicinal Materials DNA Barcode Database is a database to retrieve and analyze DNA sequences of medicinal materials. It is includes DNA sequences and information and key references of the medicinal materials recorded in the Pharmacopoeia of the People’s Republic of China, American Herbal Pharmacopoeia and other related references. Relevant information of common adulterants and substitutes are also listed. This database provides a web-based platform for storage, retrieval, comparison and analysis of DNA sequences, for distinguishing medicinal materials from their common substitutes and adulterants.

NAPROC-13- Natural Products 13C

The Natural Products 13C NMR Database, NAPROC-13, is a database provides various search tools to identify the structure of natural product compounds. Developed through a collaborative effort at the University of Salamanca and global research institutions, this resource offers a specialized database of natural product structures identified using 13C NMR spectroscopy. Acess by login.

NP-MRD Natural Products Magnetic Resonance Database

The Natural Products Magnetic Resonance Database (NP-MRD) is an open-access, web-enabled, FAIR-compliant database containing NMR spectra and structure data for all known natural products. The database accepts raw (time domain data, processed spectra, assigned chemical shifts, J-couplings, RDCs, etc.) and meta-data (structures, sources, methods, taxonomy, geospatial data, etc) from natural products. The NP-MRD includes NPs such as vitamins, minerals, and probiotics as well as small molecules derived from plants, fungi, bacteria, marine organisms, or animals.

NPASS - Natural Product Activity and Species Source Database

The Natural Product Activity and Species Source Database (NPASS) is a database provides access to unique natural products derived from organisms, alongside activity records against biological targets. It includes data on co-culture systems, engineered organisms, and comprehensive biological activity information. Users can query based on compound names, structures, or species. The database supports natural product research by offering detailed profiles of compounds, biological activities, and source organisms.

NuBBE - Núcleo de Bioensaios Biossíntese e Ecofisiologia de Produtos Naturais

NuBBEDB - Núcleo de Bioensaios Biossíntese e Ecofisiologia de Produtos Naturais is a database source of information for the scientific community of natural products and medicinal chemistry. It is an tool for studies on naturally occurring bioactive compounds, molecular and physicochemical properties, database generation, virtual screening, dereplication, metabolomics, and for the design and synthesis of bioactive compounds. NuBBE database contains a variety of natural products isolated from Braziian Biodiversity and provides information on Chemical (metabolic class, chemical structure, physicochemical properties, common and IUPAC name and molecular mass), biological (species, geographic location, biological activities), pharmacological and spectroscopic data (molar mass and nuclear magnetic resonance). This is also an effort to make natural products accessible for virtual screening in the academic community, with the 3D structure format compatible with the most widely used docking programs.

PlantMolecularTasteDB

PlantMolecularTasteDB is a database aims to integrate data about all types of orosensorially active phytochemicals (sweet, sour, bitter, salty, umami, pungent, astringent), their chemical and complete sensorial profile, and additional information about their biological activities, like anti-inflammatory activity. The Database provides several ways to explore the phytosensorial space. The phytotastants can be searched by name, chemical class, taste or other orosensations, associated taste receptors and other types of chemosensors (e.g. TRP channels), antiinflammatory activity.

PlantPepDB

PlantPepDB is a manually curated database of plant peptides having different functions and therapeutic activities. It contains peptide entries collected from databases and published research articles. Each entry provides comprehensive information about a peptide that includes its sequence, functional information, source, physicochemical properties, tertiary structure, etc. These peptides have been collected and complied from published databases and research articles. On the basis of their activities, the peptides are classified in 9 categories. The search facilitates the user to search for any field and display any field (e.g. peptide name, plant source, peptide family, peptide name, etc.). User can browse the peptides on the basis of Plant Classification, Peptide Family, Peptide Activity and Sequence Length Range.