Experimental implantation of an arterial substitute made of silicone reinforced with polyester fabric in rabbits
Clinics
; 72(12): 780-784, Dec. 2017. graf
Artigo
em Inglês
| LILACS
| ID: biblio-890704
Biblioteca responsável:
BR1.1
ABSTRACT
OBJECTIVES:
The aim of this study was to analyze silicone tubes with an internal diameter of 4 mm as a possible material for vascular prostheses.METHODS:
Grafts were implanted into the infrarenal aortas of 33 rabbits. Fluoroscopic examinations were performed within 150 days after surgical implantation. Sample grafts were analyzed via electron microscopy to evaluate the eventual endothelialization of the prostheses.RESULTS:
The patency rates of the prostheses were 87% (±6.7%) after 30 days, 73% (±9.3%) after 60 days and 48% (±12%) after 120 days. The material presented characteristics that support surgical implantation good tolerance promoted by polyester tear reinforcement, ease of postoperative removal and a lack of pseudoaneurysms. However, intimal hyperplasia was a limiting factor for the patency rate.CONCLUSIONS:
We concluded that polydimethylsiloxane has limited potential as an alternative material for small vascular prostheses.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Aorta Abdominal
/
Poliésteres
/
Desenho de Prótese
/
Silicones
/
Prótese Vascular
/
Implante de Prótese Vascular
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
Idioma:
Inglês
Revista:
Clinics
Assunto da revista:
Medicina
Ano de publicação:
2017
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade de São Paulo/BR