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Clinical effect of platelet rich fibrin in the treatment of periodontal intrabony defects. systematic review and meta-analysis

J. oral res. (Impresa); 6(5): 127-135, May 2017. ilus, tab
Artigo em Inglês | LILACS | ID: biblio-907733

BACKGROUND:

There is currently no gold standard biomaterial for the treatment of periodontal intrabony defects (PIDs). One of the current options is the use of platelet-rich fibrin (PRF).

OBJECTIVE:

To determine the clinical effect of PRF in the treatment of PID through a systematic review and meta-analysis.

MATERIALS AND METHODS:

A literature search was conducted up to February 2017 in the following biomedical databases: Pubmed, Embase, Scielo, Science Direct, SIGLE, LILACS and in the Cochrane Central Register of Clinical Trials.The selection criteria included: randomized clinical trials published in the last 5 years, reporting clinical effects (probing depth, clinical insertion level or gingival recession), with a follow-up time equal to or greater than 6 months, and sample size larger than or equal to 10 patients reporting the use of PRF as a treatment for PID. The methodological quality of the studies was analyzed using the Cochrane Handbook of Systematic Reviews of Interventions as a reference.

RESULTS:

The search strategy yielded 20 articles. A reduction in probing depth and an increase in clinical insertion level or a reduction in gingival recession is reported, when using PRF alone or in combination with another biomaterial or substance that stimulates tissue regeneration.

CONCLUSION:

The literature suggests that the use of PRF in the treatment of PIDs has a beneficial clinical effect when compared to control treatments.
Biblioteca responsável: CL30.1