Quantitative central corneal anatomy and anaesthetic eye drops effects: Comparison between 0.4% oxybuprocaine and a combination of 0.1% tetracaine and 0.4% oxybuprocaine

ABSTRACT

We aimed to analyse the changes in central cornealthickness values following the instillation of0.4% oxybuprocaine eye drops and following acombination of 0.1% tetracaine and 0.4% oxybuprocaineeye drops.Orbscan pachymetry (Orbscan II CornealTopography System; Orbscan, Inc., Salt LakeCity, UT, USA) was carried out before andthree minutes after the instillation of 0.4% oxybuprocaineeye drops, and before and threeminutes after the instillation of a combinationof 0.1% tetracaine and 0.4% oxybuprocaine eyedrops in 35 healthy subjects (n=35; aged 20-30years). After the instillation of 0.4% oxybuprocaineeye drops there was a mean increase incentral corneal thickness of 25±11 microns.After the combination of 0.1% tetracaine and0.4% oxybuprocaine eye drops it rose to 48±20microns. The combination of 0.1% tetracaineand 0.4% oxybuprocaine anaesthetic eye dropscauses higher increases in central cornealthickness values than 0.4% oxybuprocaine eyedrops (AU)

RESUMEN

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