In vitro susceptibilities of bloodstream isolates of Candida spp: results from a multicenter active surveillance program in Andalusia

ABSTRACT

Objetivos: Determinar la sensibilidad antifúngica de las cepas de Candida spp. aisladas en sangre en Andalucía, obtenidas en un estudio prospectivo multicéntrico realizado entre octubre de 2005 y septiembre de 2006. Métodos: Se aislaron 197 cepas de Candida spp. Las CMIs de anfotericina B, fluconazol, itraconazol y voriconazol se realizaron usando el panel de Sensititre YeastOne. Las CMIs de posaconazol y caspofungina se determinaron por Etest. Resultados: C. albicans (..) (AU)

ABSTRACT

Objectives The aim of this study was to determine the antifungal drug susceptibilities of Candida bloodstream isolates in Andalusia, obtained through a multicenter active laboratory-based surveillance between October 2005 and September 2006.MethodsOne hundred and ninety-seven Candida isolates were collected. The MICs of amphotericin B, fluconazole, itraconazole and voriconazole were established using the Sensititre Yeast One panel. The MICs of posaconazole and caspofungin were determined by Etest. Results C. albicans was the most frequently isolated species (49.2%), followed (..) (AU)