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Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci.
Simpson, Claire L; Wojciechowski, Robert; Oexle, Konrad; Murgia, Federico; Portas, Laura; Li, Xiaohui; Verhoeven, Virginie J M; Vitart, Veronique; Schache, Maria; Hosseini, S Mohsen; Hysi, Pirro G; Raffel, Leslie J; Cotch, Mary Frances; Chew, Emily; Klein, Barbara E K; Klein, Ronald; Wong, Tien Yin; van Duijn, Cornelia M; Mitchell, Paul; Saw, Seang Mei; Fossarello, Maurizio; Wang, Jie Jin; Polasek, Ozren; Campbell, Harry; Rudan, Igor; Oostra, Ben A; Uitterlinden, André G; Hofman, Albert; Rivadeneira, Fernando; Amin, Najaf; Karssen, Lennart C; Vingerling, Johannes R; Döring, Angela; Bettecken, Thomas; Bencic, Goran; Gieger, Christian; Wichmann, H-Erich; Wilson, James F; Venturini, Cristina; Fleck, Brian; Cumberland, Phillippa M; Rahi, Jugnoo S; Hammond, Chris J; Hayward, Caroline; Wright, Alan F; Paterson, Andrew D; Baird, Paul N; Klaver, Caroline C W; Rotter, Jerome I; Pirastu, Mario.
Afiliação
  • Simpson CL; National Human Genome Research Institute, National Institutes of Health, Baltimore, Maryland, United States of America.
  • Wojciechowski R; National Human Genome Research Institute, National Institutes of Health, Baltimore, Maryland, United States of America; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
  • Oexle K; Institute of Human Genetics, Technische Universität München, Munich, Germany.
  • Murgia F; Institute of Population Genetics, National Research Council of Italy, Sassari, Italy.
  • Portas L; Institute of Population Genetics, National Research Council of Italy, Sassari, Italy.
  • Li X; Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.
  • Verhoeven VJ; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Vitart V; MRC Human Genetics Unit, IGMM, University of Edinburgh, Edinburgh, United Kingdom.
  • Schache M; Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
  • Hosseini SM; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada, and DCCT/EDIC Research Group, The Diabetes Control and Complications Trial and Follow-up Study, The Biostatistics Center, The George Washington University, Rockville, Maryland, United States of America.
  • Hysi PG; Department of Twin Research & Genetic Epidemiology, King's College London, St Thomas' Hospital, London, United Kingdom.
  • Raffel LJ; Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
  • Cotch MF; Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Chew E; Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Klein BE; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
  • Klein R; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
  • Wong TY; Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia; Singapore Eye Research Institute, National University of Singapore, Singapore, Singapore.
  • van Duijn CM; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Mitchell P; Centre for Vision Research, Department of Ophthalmology and Westmead Millennium Institute, University of Sydney, Sydney, Australia.
  • Saw SM; Department of Epidemiology and Public Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Fossarello M; Dipartimento di Scienze Chirurgiche, Clinica Oculistica Universita' degli studi di Cagliari, Cagliari, Italy.
  • Wang JJ; Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia; Centre for Vision Research, Department of Ophthalmology and Westmead Millennium Institute, University of Sydney, Sydney, Australia.
  • Polasek O; Croatian Centre for Global Health, University of Split Medical School, Split, Croatia.
  • Campbell H; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom.
  • Rudan I; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom.
  • Oostra BA; Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands; Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, The Hague, the Netherlands.
  • Hofman A; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands; Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, The Hague, the Netherlands.
  • Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands; Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, The Hague, the Netherlands.
  • Amin N; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Karssen LC; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Vingerling JR; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Döring A; Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Bettecken T; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.
  • Bencic G; Department of Ophthalmology, Hospital "Sestre Milosrdnice", Zagreb, Croatia.
  • Gieger C; Institute of Genetic Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Wichmann HE; Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Wilson JF; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom.
  • Venturini C; Department of Twin Research & Genetic Epidemiology, King's College London, St Thomas' Hospital, London, United Kingdom.
  • Fleck B; Princess Alexandra Eye Pavilion, Edinburgh, United Kingdom.
  • Cumberland PM; MRC Centre of Epidemiology for Child Health, Institute of Child Health, University College London, London, United Kingdom.
  • Rahi JS; MRC Centre of Epidemiology for Child Health, Institute of Child Health, University College London, London, United Kingdom; Institute of Ophthalmology, University College London, London, United Kingdom; Ulverscroft Vision Research Group, Institute of Child Health, University College London, London, U
  • Hammond CJ; Department of Twin Research & Genetic Epidemiology, King's College London, St Thomas' Hospital, London, United Kingdom.
  • Hayward C; MRC Human Genetics Unit, IGMM, University of Edinburgh, Edinburgh, United Kingdom.
  • Wright AF; MRC Human Genetics Unit, IGMM, University of Edinburgh, Edinburgh, United Kingdom.
  • Paterson AD; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada, and DCCT/EDIC Research Group, The Diabetes Control and Complications Trial and Follow-up Study, The Biostatistics Center, The George Washington University, Rockville, Maryland, United States of America.
  • Baird PN; Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
  • Klaver CC; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
  • Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.
  • Pirastu M; Institute of Population Genetics, National Research Council of Italy, Sassari, Italy.
PLoS One ; 9(9): e107110, 2014.
Article em En | MEDLINE | ID: mdl-25233373
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Olho / Hiperopia / Miopia Tipo de estudo: Systematic_reviews Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Olho / Hiperopia / Miopia Tipo de estudo: Systematic_reviews Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos