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B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity.
Qian, Jason; Wang, Qiao; Dose, Marei; Pruett, Nathanael; Kieffer-Kwon, Kyong-Rim; Resch, Wolfgang; Liang, Genqing; Tang, Zhonghui; Mathé, Ewy; Benner, Christopher; Dubois, Wendy; Nelson, Steevenson; Vian, Laura; Oliveira, Thiago Y; Jankovic, Mila; Hakim, Ofir; Gazumyan, Anna; Pavri, Rushad; Awasthi, Parirokh; Song, Bin; Liu, Geng; Chen, Longyun; Zhu, Shida; Feigenbaum, Lionel; Staudt, Louis; Murre, Cornelis; Ruan, Yijun; Robbiani, Davide F; Pan-Hammarström, Qiang; Nussenzweig, Michel C; Casellas, Rafael.
Afiliação
  • Qian J; Genomics and Immunity, NIAMS, NIH, Bethesda, MD 20892, USA.
  • Wang Q; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
  • Dose M; Genomics and Immunity, NIAMS, NIH, Bethesda, MD 20892, USA. Electronic address: marei.dose@nih.gov.
  • Pruett N; Genomics and Immunity, NIAMS, NIH, Bethesda, MD 20892, USA.
  • Kieffer-Kwon KR; Genomics and Immunity, NIAMS, NIH, Bethesda, MD 20892, USA.
  • Resch W; Genomics and Immunity, NIAMS, NIH, Bethesda, MD 20892, USA.
  • Liang G; Genomics and Immunity, NIAMS, NIH, Bethesda, MD 20892, USA.
  • Tang Z; Department of Genetic and Development Biology, Jackson Laboratory for Genomic Medicine, University of Connecticut, 400 Farmington, CT 06030, USA.
  • Mathé E; Genomics and Immunity, NIAMS, NIH, Bethesda, MD 20892, USA.
  • Benner C; The Integrative Genomics and Bioinformatics Core, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Dubois W; Center of Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Nelson S; Genomics and Immunity, NIAMS, NIH, Bethesda, MD 20892, USA.
  • Vian L; Genomics and Immunity, NIAMS, NIH, Bethesda, MD 20892, USA.
  • Oliveira TY; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
  • Jankovic M; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
  • Hakim O; Bar-Ilan University, Ramat-Gan 5290002, Israel.
  • Gazumyan A; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
  • Pavri R; Institute of Molecular Pathology (IMP), Vienna BioCenter, Doktor Bohr Gasse 7, Vienna 1030, Austria.
  • Awasthi P; Science Applications International Corporation/Frederick, NCI-Frederick Cancer Research and Development Center, Frederick, MD 21702, USA.
  • Song B; Beijing Genomics Institute, Shenzhen, Shenzhen 518083, China.
  • Liu G; Beijing Genomics Institute, Shenzhen, Shenzhen 518083, China.
  • Chen L; Beijing Genomics Institute, Shenzhen, Shenzhen 518083, China.
  • Zhu S; Beijing Genomics Institute, Shenzhen, Shenzhen 518083, China.
  • Feigenbaum L; Science Applications International Corporation/Frederick, NCI-Frederick Cancer Research and Development Center, Frederick, MD 21702, USA.
  • Staudt L; Metabolism Branch, NCI, NIH, Bethesda, MD 20892, USA.
  • Murre C; Division of Biological Sciences, Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
  • Ruan Y; Department of Genetic and Development Biology, Jackson Laboratory for Genomic Medicine, University of Connecticut, 400 Farmington, CT 06030, USA.
  • Robbiani DF; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
  • Pan-Hammarström Q; Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, Huddinge, 14186 Stockholm, Sweden.
  • Nussenzweig MC; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA; HHMI, The Rockefeller University, New York, NY 10065, USA.
  • Casellas R; Genomics and Immunity, NIAMS, NIH, Bethesda, MD 20892, USA; Center of Cancer Research, NCI, NIH, Bethesda, MD 20892, USA. Electronic address: rafael.casellas@nih.gov.
Cell ; 159(7): 1524-37, 2014 Dec 18.
Article em En | MEDLINE | ID: mdl-25483777
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos B / Elementos Facilitadores Genéticos / Citidina Desaminase / Carcinogênese Limite: Animals / Humans Idioma: En Revista: Cell Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos B / Elementos Facilitadores Genéticos / Citidina Desaminase / Carcinogênese Limite: Animals / Humans Idioma: En Revista: Cell Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos