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Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the δ-opioid receptor.
Burford, Neil T; Livingston, Kathryn E; Canals, Meritxell; Ryan, Molly R; Budenholzer, Lauren M L; Han, Ying; Shang, Yi; Herbst, John J; O'Connell, Jonathan; Banks, Martyn; Zhang, Litao; Filizola, Marta; Bassoni, Daniel L; Wehrman, Tom S; Christopoulos, Arthur; Traynor, John R; Gerritz, Samuel W; Alt, Andrew.
Afiliação
  • Burford NT; †Research and Development/Discovery, Bristol-Myers Squibb Company, 5 Research Parkway, Wallingford, Connecticut 06492, United States.
  • Livingston KE; ‡Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan 48109, United States.
  • Han Y; †Research and Development/Discovery, Bristol-Myers Squibb Company, 5 Research Parkway, Wallingford, Connecticut 06492, United States.
  • Shang Y; ⊥Department of Structural and Chemical Biology Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York 10029-6574, United States.
  • Herbst JJ; †Research and Development/Discovery, Bristol-Myers Squibb Company, 5 Research Parkway, Wallingford, Connecticut 06492, United States.
  • O'Connell J; #FORMA Therapeutics, Arsenal Street, Suite 100, Watertown, Massachusetts 02472, United States.
  • Banks M; †Research and Development/Discovery, Bristol-Myers Squibb Company, 5 Research Parkway, Wallingford, Connecticut 06492, United States.
  • Zhang L; †Research and Development/Discovery, Bristol-Myers Squibb Company, 5 Research Parkway, Wallingford, Connecticut 06492, United States.
  • Filizola M; ⊥Department of Structural and Chemical Biology Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York 10029-6574, United States.
  • Bassoni DL; ∞DiscoveRx Corporation, 42501 Albrae Street, Suite 100, Fremont, California 94538, United States.
  • Wehrman TS; ×Primity Bio, 3350 Scott Boulevard, Ste 6101, Santa Clara, California 95054, United States.
  • Traynor JR; ‡Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan 48109, United States.
  • Gerritz SW; †Research and Development/Discovery, Bristol-Myers Squibb Company, 5 Research Parkway, Wallingford, Connecticut 06492, United States.
  • Alt A; †Research and Development/Discovery, Bristol-Myers Squibb Company, 5 Research Parkway, Wallingford, Connecticut 06492, United States.
J Med Chem ; 58(10): 4220-9, 2015 May 28.
Article em En | MEDLINE | ID: mdl-25901762

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Relação Estrutura-Atividade / Receptores Opioides delta Limite: Animals Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Relação Estrutura-Atividade / Receptores Opioides delta Limite: Animals Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos